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PPRNet - Primary (Care) Practices Research Network


Cara B. Litvin, J. Madison Hyer, and Steven M. Ornstein. Use of Clinical Decision Support to Improve Primary Care Identification and Management of Chronic Kidney Disease (CKD).
J Am Board Fam Med. September-October 2016; 29:604-612.


Cara B. Litvin, MD, MS; Steven M. Ornstein, MD; Andrea M. Wessell, PharmD; and Lynne S. Nemeth, RN, PhD. “Meaningful” Clinical Quality Measures for Primary Care Physicians.  American Journal of Managed Care.  Published Online: November 13, 2015.

Steven M. Ornstein, MD, Lynne S. Nemeth, RN, PhD, Paul J. Nietert, PhD, Ruth G. Jenkins, PhD, Andrea M. Wessell, PharmD, and Cara B. Litvin, MD, MS. Learning from Primary Care Meaningful Use Exemplars. J Am Board Fam Med. 2015 May-June; 28 (3):360-370.


Wessell AM, Nemeth LS, Jenkins RG, Ornstein SM, Miller PM. Medications for Alcohol Use Disorders in a Primary Care Practice-Based Research Network Implementation Study. Alcoholism Treatment Quarterly. 2014;32(1):58-66. 

Litvin, CB, Ornstein, SM. Quality Indicators for Primary Care;  An Example for Chronic Kidney Disease. J Ambulatory Care Manage, 2014 37(2):171–178.


Ornstein SM, Nietert PJ, Jenkins RG, Litvin CB: The Prevalence of Chronic Diseases and Multimorbidity in Primary Care Practice: A PPRNet Report.  J Am Board Fam Med 2013 Sept-Oct; 26 (5):518-524.  American Journal of Managed Care. 2015 

Ornstein, SM, Jenkins, RG, Litvin, CB, Wessell, AM, Nietert, PJ. Preventive Services Delivery in Patients With Chronic Ilnesses: Parallel Opportunities Rather Than Competing Obligations. Ann Fam Med. 2013 Jul-Aug;11(4):344-9.

 Litvin, CB, Ornstein, SM, Wessell, AM, Nemeth, LS, Nietert, PJ. Use of an Electronic Health Record Clinical Decision Support Tool to Improve Antibiotic Prescribing for Acute Respiratory Infections: The ABX-TRIP Study.
J Gen Intern Med. 2013 Jun;28(6):810-6.

Nemeth, LS, Miller, PM, Nietert, PJ, Ornstein, SM, Wessell, AM, Jenkins, RG. Organizational Attributes and Screening and Brief Intervention in Primary Care. Addict Behav. 2013 Jun 14;38(11):2639-2642.

Ornstein, SM, Miller, PM, Wessell, AM, Jenkins, RG, Nemeth, LS, Nietert, PJ. Integration and Sustainability of Alcohol Screening, Brief Intervention, and Pharmacotherapy in Primary Care Settings.  J Stud Alcohol Drugs. 2013 Jul;74(4):598-604.

Wessell, A. M., S. M. Ornstein, et al. (2013). "Medication Safety in Primary Care Practice: results from a PPRNet quality improvement intervention." Am J Med Qual 28(1): 16-24.         


Nemeth LS, Ornstein SM, Jenkins RG, Wessell Am, Nietert PJ. Implementing and Evaluating Electronic Standing Orders in Primary Care Practice: A PPRNet Study. Journal of the American Board of Family Medicine Sept-Oct 2012, Volume 25, Issue 4, 594-604.

Litvin, CB, Ornstein, SM, Wessell, AM, Nemeth, LS, Nietert, PJ. Adoption of a clinical decision support system to promote judicious use of antibiotics for acute respiratory infections in primary care, International Journal of Medical Informatics, Volume 81, Issue 8, August 2012, Pages 521-526. PMID:22483528. 


Litvin C, Nietert PJ, Wessell AM, Jenkins RG, Ornstein SM: Recognition and Management of CKD in Primary Care, American Journal of Kidney Diseases 2011, Vol. 57, Issue 4, 646-647. PMID: 21257244.

Nemeth, L. S., R. G. Jenkins, et al. (2011). "Colorectal cancer screening in primary care: theoretical model to improve prevalence in the practice partner research network." Health Promotion Practice 12(2): 229-234.


Nemeth LS, Wessell AM. Improving Medication Safety in Primary Care Using Electronic Health Records. Journal of Patient Safety, 2010, 6(4); 238-243 

Ornstein SM, Nemeth LS, Jenkins RG, Nietert PJ: Colorectal Cancer Screening in Primary Care – Translating Research into Practice, Medical Care, 48(10):900-906 

Wessell AM, Litvin C, Jenkins RG, Nietert PJ, Nemeth LS, Ornstein SM. Medication Prescribing and Monitoring Errors in Primary Care: A Report from the Practice Partner Research Network. Qual. Saf. Health Care, 10.1136/qshc.2009.034678. 


Nemeth LS, Jenkins RG, Nietert PJ, Ornstein SM: Colorectal Cancer Screening in Primary Care: Theoretical Model to Improve Prevalence in the Practice Partner Research Network, Health Promotion Practice, 2009, March 18. PubMed Central ID PMC2889237. 

Nietert PJ, Jenkins RG, Nemeth LS, Ornstein SM (2009). An application of a modified constrained randomization process to a practice-based cluster randomized trial to improve colorectal cancer screening. Contemporary Clinical Trials, 30:129-132 

Nemeth LS, Nietert PJ and Ornstein SM: High Performance in Screening for Colorectal Cancer: A Practice Partner Research Network (PPRNet) Case Study. Journal of the American Board of Family Medicine, 2009, 22: 141-146, PMCID: PMC2696281


Rose HL, Miller PM, Nemeth LS, Jenkins RG, Nietert PJ, Wessell AM. Alcohol screening and brief counseling in a primary care hypertensive population: a quality improvement intervention. Addiction 2008; 103 (8): 1271-1280 

Bradford WD, Kleit AN, Nietert PJ, Ornstein SM (2008). The effect of direct to consumer television advertising on the timing of treatment. Economic Inquiry, 48(2): 306-322. DOI: 10.1111/j.1465-7295.2009.00215.x. 

Wessell AM, Nietert PJ, Jenkins RG, Nemeth LS, Ornstein SM: Inappropriate Medication Use in the Elderly: Results from a Quality Improvement Project in 99 Primary Care Practices. The American Journal of Geriatric Pharmacotherapy, 2008, 6(1):21-27 

Wessell AM, Liszka HA, Nietert PJ, Jenkins RG, Nemeth LS, Ornstein S: Achievable Benchmarks of Care for Primary Care Quality Indicators in a Practice-Based Research Network. American Journal of Medical Quality 2008, 23(1):39-46 

Ornstein SM, Nietert PJ, Jenkins RG, Wessell AM, Nemeth LS, Roylance L, Liszka H: Improving the translation of research into primary care practice: results of a national quality improvement demonstration project. Joint Commission Journal on Quality and Patient Safety, 2008, 34(7); 379-390

Nemeth LS, Feifer C, Stuart GW, Ornstein SM: Implementing change in primary care practices using electronic medical records: a conceptual framework, Implementation Science 2008, 3:3 (16 Jan 2008) 


Nemeth, Lynne S, Wessell, Andrea M, Jenkins, Ruth G, Nietert, Paul J, Liszka, Heather A, Ornstein, Steven M: Strategies to Accelerate Translation of Research into Primary Care Within Practices Using Electronic Medical Records. Journal of Nursing Care Quality, 2007, 22(4): 343-349 

Feifer C, Nemeth L, Nietert PJ, Wessell AM, Jenkins RG, Roylance LF, Ornstein SM: Different Paths to High-Quality Care: Three Archetypes of Top Performing Practice Sites. Annals of Family Medicine, 2007, 5(3): 233-241 

Nietert PJ, Wessell A, Jenkins RG, Feifer C, Nemeth LS, Ornstein SM. Using a summary measure for multiple quality indicators in primary care: the Summary Quality Index (SQUID). Implementation Science 2007; 2:11. 

Ornstein SM, Nietert PJ, Jenkins RG, Wessell AM, Feifer C, Corley ST: Improving Diabetes Care through a Multi-component Quality Improvement Model in a Practice-Based Research Network. American Journal of Medical Quality, 2007, 22(1): 34-41 


Bradford WD, Kleit AN, Nietert PJ, Ornstein SM: Effects of Direct-to-Consumer Advertising of Hydroxymethylglutaryl Coenzyme A Reductase Inhibitors on Attainment of LDL-C Goals, 2006, Clinical Therapeutics, 28(12): 2105-2118 

Bradford W, Kleit A, Nietert P, Steyer T, McIlwain T, Ornstein S: How direct to consumer television advertising for osteoarthritis drugs affects physicians' prescribing behavior, 2006, Health Affairs, 25(5):1371-1377 

Nietert Paul J, Wessell Andrea M, Feifer Chris, Ornstein Steven M: Effect of Terminal Digit Preference on Blood Pressure Measurement and Treatment in Primary Care, American Journal of Hypertension, 2006, 19(2): 147-152 

Jenkins RG, Ornstein SM, Nietert PJ, Klockars SJ, Thiedke C: Quality Improvement for Prevention of Cardiovascular Disease and Stroke in an Academic Family Medicine Center: Do Racial Differences in Outcome Exist? Ethnicity & Disease, 2006, 16: 132-137 

Feifer C, Ornstein SM, Jenkins RG, Wessell AM, Corley ST, Nemeth LS, Roylance L, Nietert PJ, Liszka, H: The logic behind a multi-method intervention to improve adherence to clinical practice guidelines in a nationwide network of primary care practices. Evaluation & the Health Professions, 2006, 29(1): 65-88 


Brewer B: Quality Rankings Can Work, For Patients and Doctors, The Wall Street Journal On-Line, November 2005 


Ornstein SM, Jenkins RG, Nietert PJ, Feifer C, Roylance LF, Nemeth L, Corley S, Dickerson L, Bradford WD, Litvin, C: Multi-Method Quality Improvement Intervention to Improve Cardiovascular Care: A Cluster Randomized Trial, Annals of Internal Medicine, 2004; 141(7):523-532 

Nietert PJ, Ornstein SM, Jenkins RG, Roylance LF, Dickerson L, Feifer C. The effect of ethnicity on outcomes in a practice-based trial to improve cardiovascular disease prevention. International Journal for Equity in Health, 2004; 3:12 

Feifer C, Ornstein SM: Strategies for Increasing Adherence to Clinical Guidelines and Improving Patient Outcomes in Small Primary Care Practices. The Joint Commission Journal on Quality and Safety 2004; 30(8): 432-441 

Miller PM, Ornstein SM, Nietert PJ, Anton RF: Self-report and biomarker alcohol screening by primary care physicians: The need to translate research into guidelines and practice. Alcohol and Alcoholism, 2004; 39(4): 325-328 

Feifer C, Fifield J, Ornstein S, et al: From Research to Daily Clinical Practice: What Are the Challenges in “Translation?” The Joint Commission Journal on Quality and Safety, 2004; 30(5):235-245 

Ornstein SM, Nietert PJ, Dickerson LM: Hypertension Management and Control in Primary Care: A Study of 20 Practices in 14 States, Pharmacotherapy, 2004; 24(4): 500-507 


Stuart GW, Laraia MT, Ornstein SM, Nietert PJ: An interactive voice response system to enhance antidepressant medication compliance. Topics in Health Information Management 2003; 24(1):15-20 

Ornstein SM: Practicing Beautiful Medicine Beautifully: Hiram Curry’s Vision in the 21st Century Journal of the SC Medical Association 2003; 99: 227-232 

Nietert PJ, Ornstein SM, Dickerson LM, Rothenberg RJ: Comparison of Changes in Blood Pressure Measurements and Anti-hypertensive Therapy in Older Hypertensive Ambulatory Care Patients Prescribed Celecoxib or Rofecoxib. Pharmacotherapy 2003;23:1416-1423 

Wessell AM, Ornstein SM, Nietert PJ, Wilson JP, Brooks A: Achieving Blood Pressure Control in Patients with Diabetes. A Case Study in Primary Care. Topics in Health Information Management, 2003; 24(1): 3-7 


Nietert PJ, Jenkins RG, Ornstein SM: Improving patient cardiovascular outcomes through physician practice-level intervention: power, sample size, and analysis considerations. American Journal of Epidemiology, 2001; 153(11):S264. 

Ornstein, SM: Translating Research into Practice Using Electronic Medical Records. The PPRNet-TRIP Project: Primary and Secondary Prevention of Coronary Heart Disease and Stroke. Topics in Health Information Management, 2001; 22(2): 52-58 

Litvin CB, Ornstein SM, Anthony WE, Tanner D: Quality Improvement Using Electronic Medical Records: A Case Study of a High-Performing Practice. Topics in Health Information Management, 2001; 22(2): 59-64 

Feifer C, Ornstein SM, Nietert PJ, Jenkins RG: System Supports for Chronic Illness Care and Their Relationship to Clinical Outcomes. Topics in Health Information Management, 2001; 22(2): 65-72 

Ornstein SM, Hanson RM, Corley ST, Jenkins RG: High Performance of Clinical Preventive Services: Approaches of “Best Practices”, Preventive Medicine in Managed Care, 2001; 2(2): 79-84 


Hueston WJ, Jenkins RG, Mainous AG: Does Drug Treatment of Patients with Acute Bronchitis Reduce Additional Care Seeking? Arch Fam Med , 2000: 9:997-1001 

Wager KA, Lee FW, White AW, Ward DM, Ornstein SA. Impact of an Electronic Medical Record System on Community-Based Primary Care Practices. J Am Board Fam Pract 2000;13:338-48 

Pan Q, Ornstein SM, Gross A, Hueston WJ, Jenkins RG, Mainous AG, Silverstein MD: Antibiotics and Return Visits for Respiratory Illness: A Comparison of Pooled versus Hierarchical Statistical Methods. The American Journal of Medical Sciences 2000; 319(6):560-365 

Gauthier BM, Hickner JM, Ornstein SM: High Prevalence of Overweight Children and Adolescents in the Practice Partner Research Network. Archives of Pediatrics and Adolescent Medicine 2000; 154:625-628 

Jenkins RG, Ornstein SM: Preventive Services in the Primary Care Practices of the Practice Partner Research Network. Topics in Health Information Management 2000; 20(3):80-84 

Ornstein SM, Stuart G, Jenkins RG: Depression and Antidepressants in Primary Care Practice. A Study from the Practice Partner Research Network (PPRNet). The Journal of Family Practice. 2000; 49(1):68-72 


Hueston WJ, Mainous AG, Ornstein S, Pan Q, Jenkins RG: Antibiotics for Upper Respiratory Infections. Follow-up Utilization and Antibiotic Use. Arch Fam Med. 1999; 8:426-430 

Ornstein SM, Jenkins RG: Quality of Care for Chronic Illness in Primary Care: Opportunity for Improvement in Process and Outcome Measures. The American Journal of Managed Care. 1999; 5(5):621-627 

Hueston WJ, Ornstein SM, Jenkins RG, Pan Q, Wulfman JS: Treatment of Recurrent Otitis Media After a Previous Treatment Failure - Which Antibiotics Work Best? The Journal of Family Practice. 1999; 48(1):43-46 


Ornstein SM, Jenkins RG, MacFarlane L, Glaser A, Snyder K, Gundrum T: Electronic Medical Records as Tools for Quality Improvement in Ambulatory Practice: Theory and a Case Study. Topics in Health Information Management. 1998; 19(2):35-43 

Ornstein SM, Ury A, Corley S: Using the EMR - Electronic Medical Record is Critical tool in Primary Care Research. Physician and Computers. 1998; 16(4):10-15 


Wager KA, Ornstein SM, Jenkins RG: The Perceived Value of Computer Based Patient Records Among Clinician Users. MD Computing, September 1997; 14(5)

Ornstein SM, Jenkins RG: The Practice Partner Research Network: Description of a Novel National Research Network of Computer-based Patient Records Users. Carolina Health Services and Policy Review. 1997, 4:145-151



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