
Alzheimer's Research & Clinical Trials Programs (ARCP)
Definitions
Amyloid Plaques
A largely insoluble deposit found in the space between nerve cells in the brain. Plaques are made of beta-amyloid, other molecules, and different kinds of nerves and nerve molecules.
Neurofibrillary Tangles
Twisted fibers of a protein called Tau that forms inside of dying cells.
U.S. Department of Health and Human Services: NIH Publication Number 08-3782. "Alzheimer's Disease: Unraveling the Mysery." pgs.70 and 73. September 2008.



