Department of Craniofacial Biology

Dr. Andrew G. Jakymiw

dr. jakymiw


 Andrew G. Jakymiw, PhD
 Assistant Professor
 Department of Craniofacial Biology

Contact Information
jakymiw@musc.edu
BSB 230C
173 Ashley Ave
MSC 507
Charleston, SC 29425
Phone: 843-792-2551

Education:
Ph.D., University of Calgary
Postdoctoral training, University of Florida

Honors and Awards:
Canadian Institutes for Health Research Studentship (1997-2002)
Alberta Heritage Foundation for Medical Research Incentive Award (2001-2002)
Alberta Heritage Foundation for Medical Research Studentship Award (2002-2003)
American Society for Cell Biology Postdoctoral Travel Award (2005) 
Bankhead-Coley Florida Cancer Research Program New Investigator Research Grant (2008-2011)
K99/R00 NIH Pathway to Independence Award (NIDCR; 2008-2013)   

Department Affiliations:
Craniofacial Biology

Research Interests:
Our research focuses on the study of RNA interference (RNAi) biology and how dysregulation of its molecular components can contribute to disease, in particular oral cancer.  Moreover, our laboratory is also pursuing the study of RNAi-based therapies for oral cancer.  The goal of our research is to gain further insights into the molecular causes of oral cancer, identify novel biomarkers for this disease, and develop novel therapeutic strategies for treating oral cancer.

Recent Publications:
Qin, Z., A. Jakymiw, V. Findlay, C. Parsons. KSHV-Encoded MicroRNAs: Lessons for Viral Cancer Pathogenesis and Emerging Concepts. International Journal of Cell Biology. 2012:603961. (2012; Epub) PMID: 22505930 PMCID: PMC3296157

Palanisamy V., A. Jakymiw, E.A. Van Tubergen, N.J. D'Silva, K.L. Kirkwood. Control of Cytokine mRNA Expression by RNA-binding Proteins and microRNAs. Journal of Dental Research. (2012; Epub ahead of print) PMID: 22302144

Patel, R.S., A. Jakymiw, B. Yao, B.A. Pauley, W.C. Carcamo, J. Katz, J.Q. Cheng, E.K.L. Chan. High resolution of microRNA signatures in human whole saliva. Archives of Oral Biology. 56:1506-13 (2011) PMID: 21704302 PMCID: PMC3189266

Katz, J., A. Jakymiw, M.K. Ducksworth, C.M. Stewart, I. Bhattacharyya, S. Cha, E.K.L. Chan. CIP2A expression and localization in oral carcinoma and dysplasia. Cancer Biology & Therapy. 10:694-699 (2010) PMID: 21068540 PMCID: PMC3230513

Jakymiw, A., R.S. Patel, N. Deming, I. Bhattacharyya, P. Shah, R.J. Lamont, C.M. Stewart, D.M. Cohen, E.K.L. Chan. Overexpression of Dicer as a result of reduced let-7 microRNA levels contributes to increased cell proliferation of oral cancer cells. Genes, Chromosomes & Cancer. 49:549-559 (2010) PMID: 20232482 PMCID: PMC2859695