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Cystic Fibrosis Center


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Articles (peer reviewed):

  1. Flume PA, Mogayzel PJ, Robinson KA, Rosenblatt RL, Quittell L, Marshall BC.  Cystic fibrosis pulmonary guidelines: pulmonary complications: hemoptysis and pneumothorax.  Am J Respir Crit Care Med 2010 (in press).
     
  2. Mojayzel PJ, Flume PA. Update in cystic fibrosis 2009.  Am J Respir Crit Care Med 2010; 181: 539-544.
     
  3. Flume PA, Ciolino J, Gray S, Lester MK.  Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis.  J Cyst Fibr 2009; 8: 321-325.
     
  4. Flume PA, Mogayzel PJ, Robinson KA, Goss CH, Rosenblatt RL, Kuhn RJ, Marshall BC, and the Clinical Practice Guidelines for Pulmonary Therapies Committee. Cystic fibrosis pulmonary guidelines: treatment of pulmonary exacerbations.  Am J Respir Crit Care Med 2009; 180: 802-808.
     
  5. Ghegan MD, Wise SK, White DR, Flume PA, Bowman CM, Virella-Lowell I, Schlosser RJ. Cost-effective airway cultures in the cystic fibrosis patient. Am J Otolaryngol 2009; 30: 150-2.
     
  6. Lester MK, Flume PA. Airway clearance therapy: guidelines and implementation. Respir Care 2009; 54: 733-750.
     
  7. Flume PA.  Pulmonary complications of cystic fibrosis.  Respir Care 2009; 54: 618-627.
     
  8. Flume PA, Robinson KA, O'Sullivan BP, Finder JD, Vender RL, Willey-Courand DB, White TB, Marshall BC,  and the Clinical Practice Guidelines for Pulmonary Therapies Committee.  Cystic fibrosis pulmonary guidelines: airway clearance therapies.  Respir Care 2009; 54: 522-537.
     
  9. Flume PA.  A role for aerosolized antibiotics.  Pediatr Pulmonol 2008; 43: S29-34.
     
  10. Stenbit A, Flume PA.  Pulmonary complications in adult patients with cystic fibrosis.  Am J Med Sci 2008; 335: 55-59.
     
  11. Flume PA, Stenbit A. Making the diagnosis of cystic fibrosis.  Am J Med Sci 2008; 335: 51-54.
     
  12. Flume PA, O'Sullivan BP, Robinson KA, Goss CH, Mogayzel PJ, Willey-Courand DB, Bujan J, Finder J, Lester M, Quittell L, Rosenblatt R, Vender RL, Hazle L, Sabadosa K, Marshall B.  Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health.  Am J Respir Crit Care Med 2007; 176: 957-969.
     
  13. Woodworth BA, Ahn C, Flume PA,  Schlosser RJ.  The delta F508 mutation in cystic fibrosis and impact on sinus development.  Am J Rhinol 2007; 21:122-7.
     
  14. Ford D, Flume PA.  Impact of lung transplantation on site of death in cystic fibrosis.  J Cyst Fibr 2007; 6: 391-395.
     
  15. Heaney DL, Flume P, Hamilton L, Lyon E, Wolff DJ.  Detection of an apparent homozygous 3120G>A cystic fibrosis mutation on a routine carrier screen.  J Molec Diagn. 2006; 8:137-40.
     
  16. Garwood S, Flume PA, Ravenel J.  Superior vena cava syndrome related to indwelling intravenous catheters in patients with cystic fibrosis.  Pediatr Pulmonol 2006; 41: 683-687.
     
  17. Sheridan MB, Fong, P, Groman JD, Conrad C, Flume P, Diaz R, Harris C, Knowles M, Cutting GR.  Mutations in the beta subunit of the epithelial Na+ channel in patients with a cystic fibrosis-like syndrome.  Hum Molec Genet 2005; 14:3493-3498.
     
  18. Flume PA, Yankaskas JR, Ebeling M, Hulsey T, Clark LL.  Massive hemoptysis in cystic fibrosis.  Chest 2005; 128: 729-738.
     
  19. Flume PA, Strange C, Ye X, Ebeling M, Hulsey T, Clark LL.  Pneumothorax in cystic fibrosis.  Chest 2005; 128: 720-728.
     
  20. Flume PA, Gray S, Bowman CM, Kerrigan C, Lester M, Virella-Lowell I.  Hurricane preparedness for the patient with cystic fibrosis. Am J Nurs 2005; 105: 68-72.
     
  21. Lester MK, Flume PA, Gray SL, Anderson D, Bowman CM.  Nebulizer use and maintenance by cystic fibrosis patients:  a survey study.  Respir Care 2004; 49: 1504-1508.
     
  22. Bosso JA, Flume PA, Gray S.  Pharmacokinetics of linezolid in adult patients with cystic fibrosis.  Antimicrob Agent Chemother 2004; 48: 281-284.
     
  23. Flume PA, Taylor LA, Anderson DL, Gray S, Turner D.  Transition programs in cystic fibrosis centers: perceptions of team members.  Pediatr Pulmonol 2004; 37: 4-7.
     
  24. Flume PA.  Pneumothorax in cystic fibrosis.  Chest 2003; 123: 217-221.
     
  25. Flume PA, Klepser ME.  The rationale for aerosolized antibiotics.  Pharmacother 2002; 22: 71S-79S.
     
  26. Anderson DL, Flume PA, Hardy KK, Gray S.  Transition programs in cystic fibrosis centers: perceptions of patients.  Pediatr Pulmonol 2002; 33: 327-331.  Editorial: Schidlow DV.  Pediatr Pulmonol 2002; 33: 325-326.
     
  27. Flume PA, Anderson DL, Hardy KK, Gray S.  Programs of transition in cystic fibrosis centers: perceptions of pediatric and adult program directors.  Pediatr Pulmonol 2001; 31: 443-450.
     
  28. Anderson DL, Flume PA, Hardy KK.  Psychological functioning of adults with cystic fibrosis.  Chest 2001; 119: 1079-1084.
     
  29. Nichols L, Flume PA.  Complications of cystic fibrosis in adults.  J SC Med Assoc 2000; 96: 112-117.
     
  30. Bosso JA, Bonapace CR, Flume PA, White RL.  A pilot study of the efficacy of constant infusion ceftazidime in the treatment of endobronchial infections in adults with cystic fibrosis.  Pharmacotherapy 1999; 19: 620-626.
     
  31. Flume PA.  Cystic fibrosis: when to consider lung transplantation? (editorial).  Chest 1998; 113: 1159-1161.
     
  32. Manduru M, Mihm LB, White RL, Friedrich LV, Flume PA, Bosso JA.  Comparative bactericidal activity against isolates of Pseudomonas aeruginosa as assessed in an in vitro pharmacodynamic model versus the traditional time-kill method.  Antimicrob Agents Chemother 1997; 41: 2527-2532.
     
  33. Manduru M, Mihm LB, White RL, Friedrich LV, Flume PA, Bosso JA.  In vitro pharmacodynamics of ceftazidime against Pseudomonas aeruginosa isolates from cystic fibrosis patients.  Antimicrob Agents Chemother 1997; 41: 2053-2056.
     
  34. Flume PA.  Current and novel therapies for cystic fibrosis.  J SC Med Assoc 1996; 92: 375-382.
     
  35. Steinbach S, Sun L, Jiang RZ, Flume P, Gilligan P, Egan TM, Goldstein R.  Transmissibility of Pseudomonas cepacia infection in clinic patients and lung-transplant recipients with cystic fibrosis.  N Engl J Med 1994; 331: 981-987.
     
  36. Flume PA, Egan TM, Paradowski LJ, Detterbeck FC, Thompson JT, Yankaskas JR.  Infectious complications of lung transplantation: impact of cystic fibrosis.  Am J Respir Crit Care Med 1994; 149: 1601-1607.

Articles (invited/non-peer reviewed):

  1. Flume PA. Smoothing the transition from pediatric to adult care: lessons learned. Curr Opin Pulm Med 2009; 15: 611-614.
     
  2. Flume PA.  Pulmonary exacerbations: what do we know and what should we know? Pediatr Pulmonol 2009; Supp. 32: 144-145.
     
  3. O’Sullivan BP, Flume P.  The clinical approach to lung disease in patients with CF.  Semin Respir Crit Care Med 2009; 30:505-13.
     
  4. Flume PA.  Chronic antibiotic therapy for patients with cystic fibrosis.  Commentaries on Chronic Airways Infection 2007; 1 (3): 2-7.
     
  5. Flume PA.  Macrolides.  Commentaries on Chronic Airways Infection 2007; 1 (1): 13-19.
     
  6. Flume PA.  Transition in CF: where are we now?. Cystic Fibrosis Worldwide Newsletter 2006.
     
  7. Flume P.  Disaster situations: patients with special needs.  National Respiratory Training Center Update, December 2005.
     
  8. Flume PA.  Airway clearance techniques.  Semin Respir Crit Care Med 2003; 24: 727-735.
     
  9. Flume PA.  A study of the transition process. Cystic Fibrosis Worldwide Newsletter 2002; 2: 21-24.
     
  10. Kuhn RJ, Flume PA.  Treatment options for cystic fibrosis: case study and panel discussion.  Pharmacother 2002; 22: 86S-87S.

Case Reports:

1.            Dave S, Flume PA, Honney S, Raymond J.  An unusual presentation of cystic fibrosis in an adult.  Am J Kidney Dis 2005; 45: e41-44.

2.            Highland KB, Flume PA.  A story of a woman with cystic fibrosis.  Chest 2002; 121: 1704-1717.  Editorial: Kitchens CS.  Chest 2002; 121: 1392-1393.

Chapters:

  1. Flume PA.  Cystic Fibrosis.  In: The Educational Review Manual in Pulmonary Disease – 2007, Doherty D and Make B (eds), New York, NY: Castle Connolly Graduate Medical Publishing, Inc.
     
  2. Flume PA.  Cystic Fibrosis.  In: The Educational Review Manual in Pulmonary Disease – 2005, Doherty D and Make B (eds), New York, NY: Castle Connolly Graduate Medical Publishing, Inc.
     
  3. Flume PA.  Cystic Fibrosis.  In: The Educational Review Manual in Pulmonary Disease – 2003, Doherty D and Make B (eds), New York, NY: Castle Connolly Graduate Medical Publishing, Inc.
     
  4. Flume PA, Yankaskas JR.  Reproductive Issues.  In: Cystic Fibrosis in Adults, JR Yankaskas and MR Knowles (eds), Hagerstown MD: Lippincott-Raven; 1999: 449-464.

Consensus Documents:

  1. Yankaskas JR et al. Cystic Fibrosis Adult Care; Consensus conference report. Chest 2004; 125 (Suppl): 1S-39S.
     
  2. Yankaskas JR et al. Cystic Fibrosis Adult Care.  In: Consensus Conferences 1999; 9 (3): 1-51.

Educational Materials:

  1. Flume PA.  Management of pulmonary complications in the patient with cystic fibrosis. Pulmonary and Critical Care Update, Volume 23, Lesson 1, 2008.
     
  2. Moreo, K, Flume PA.  New directions in the management of cystic fibrosis disease.  Professional Resources in Management Education, 2003.