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 COHR: Center for Oral Health Research | Oral Histology & Digital Imaging Core | Mineralized Tissue Imaging | L-COHR Imaging

Digital Imaging and Slide Scanning

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The Laboratory Core (L-COHR) within the Center for Oral Health Research is dedicated to providing MUSC researchers with the equipment, techniques, and technical expertise necessary to study all aspects of oral health and disease.  L-COHR services are available to researchers at MUSC and other institutions. The facility is equipped with state of the art equipment and experienced staff to assist both new and experienced researchers.  To reserve time on equipment or request imaging or analysis by Core staff, please visit our iLab Site (

Researchers are encouraged to consult with L-COHR staff prior to sample preparation.  Staff are available for:
•Assistance with sample preparation, processing and analysis
•Experimental design consultation
•Training in specialized techniques

Digital image acquisition and analysis
The facility operates an upright Olympus BX61 automated microscope equipped with a digital color camera and motorized stage, 1.25x-60x magnification, and brightfield and fluorescent illumination.  Acquisition software includes both CellSens for simple imaging and VisioPharm for automated imaging essential for TMAs and more complex studies (available through Core staff only).  Images can be analyzed for a variety of parameters using VisioPharm or Bioquant analysis software.

Available services include:
•Static and dynamic histomorphometry
•Brightfield and fluorescent image acquisition
•Automated image analysis
•TMA scanning

Dell workstations running CellSens Dimension and VisioPharm software packages for digital image analysis.  The PC is also loaded with Adobe Photoshop CS for use at no charge.
Contact Information: 

James Cray Jr, PhD
Assistant Professor

Lixia Zhang, PhD
Research Specialist
BSB 129