microCT Scanning and Analysis
The Laboratory Core (L-COHR) within the Center for Oral Health Research is dedicated to providing MUSC researchers with the equipment, techniques, and technical expertise necessary to study all aspects of oral health and disease. L-COHR services are available to researchers at MUSC and other institutions. The facility is equipped with state of the art equipment and experienced staff to assist both new and experienced researchers. To reserve time on equipment or request imaging or analysis by Core staff, please visit our iLab Site (musc.ilabsolutions.com).
Researchers are encouraged to consult with L-COHR staff prior to sample preparation. Staff are available for:
•Assistance with sample preparation, processing and analysis
•Experimental design consultation
•Training in specialized techniques
microCT scanning and analysis
L-COHR operates a Scanco uCT40 ex vivo scanner with an analysis workstation and server. The uCT40 is capable of up to 6 um resolution scanning of samples up to 6 mm in diameter. Larger samples (up to 35 mm diameter) can be scanned at lower resolutions.
Some available analyses include:
•Analysis of trabecular and cortical bone parameters
•Bone volume fraction analysis
•Mineral density analysis
•2D and 3D measurements
Please use the iLab website (musc.ilabsolutions.com) to request services or schedule equipment use.
•Faxitron LX-60 X-ray cabinet for generation of high resolution X-ray images. This equipment provides high quality 2D X-ray images of samples both in vivo and ex vivo. Training by and approval of L-COHR staff is required prior to use.
•Dell workstations running ImageJ and GE MicroView software packages for scan analysis.
Chad Novince, DDS, PhD
Hong Yu, MD
Lixia Zhang, PhD