Altered Structure and Function A 2011 is a theme designed to provide insight into the altered molecular, genetic, and biochemical processes, disturbed physiology, and resulting morphologic changes that occur at the subcellular and cellular level within tissues of the body during various disease states.  The initial portion of the theme emphasizes general concepts.  The theme then transitions into the application of the general concepts to systems-based disease, to include hematologic, dermatologic, pediatric, reproductive, and endocrine disorders.  Incorporated into the study of the altered physiology, genetic, and morphologic changes encountered in disease processes is the efficient use of the clinical laboratory in patient diagnosis and monitoring through the understanding of test methods, selection, and significance.   The discipline of medical genetics is incorporated in the theme and crosses all areas of medicine. Over the four years of medical school, medical genetic education is designed to teach you the knowledge that will allow you to apply genetic principles to your practice.