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Student Profiles-Alfred Griffin
2nd year DMSTP student

Undergraduate Institution
University of Virginia

Research

My research focus is on the mechanisms of osteoclast activation and differentiation as it relates to cytokine biology and the innate immune response. More specifically, I am interested in the role of MKP-1 in regulating the p38 MAP Kinase cascade in osteoclasts.

Mentor and Department
Dr. Keith Kirkwood DDS, PhD
Medical University of South Carolina


Abstracts/Meetings

Y. Bi, T. M. Kilts, A.C. Griffin, M. F. Young. “Biglycan and Fibromodulin Control Bone Mass by Regulating Osteoclast Differentiation Through Bone Marrow Stromal Cells”. American Society for Bone and Mineralization Research Annual Conference. Honolulu, HI. September 16th, 2007

A.C. Griffin, S. Yuvaraj, K. Sundaram, W.L. Ries and S.V. Reddy. “CXC Chemokine Ligand-13 Stimulates RANK Ligand Expression in Squamous Cell Carcinoma” American Society for Bone and Mineralization Research Annual Conference. Montreal, Quebec. August 12th, 2008

Publications
Buff H., Smith AC, Korey CA. Genetic modifiers of Drosophila palmitoyl-protein thioesterase 1-induced degeneration. Genetics. 2007 May;176(1):209-20.

Bannan BA, Van Etten J, Kohler JA, Tsoi Y, Hansen NM, Sigmon S, Fowler E, Buff H, Williams TS, Ault JG, Glaser RL, Korey CA. The Drosophila protein palmitoylome: Characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. Fly (Austin). 2008 Jul 15;2(4).

Honors and Awards
Intramural Research Training Award, National Institute of Dental and Craniofacial Research, May-August 2006
Intramural Research Training Award, National Institute of Dental and Craniofacial Research, March-May 2007
CLARION Interprofessional Case Competition 2008, 3rd place ($1000). http://academicdepartments.musc.edu/musc/news/univ_news/dec08clarion.htm
1st place ($500), PhD I Category The 2008 Perry V. Halushka MUSC Student Research Day. “CXC Chemokine Ligand-13 Stimulates RANK Ligand Expression in Squamous Cell Carcinoma”. November, 2008.

Recently Attended Meetings

2008 American Association for Dental Research. Dallas, TX. March 2008.
2008 American Society for Bone and Mineralization Research Annual Conference. Montreal, Quebec. August, 2008.
National Institutes of Dental and Craniofacial Biology DDS/PhD Training Workshop. Bethesda, MD. September 2008.
 
Links

 - Center for Oral Health Research
 - SC COBRE for Oral Health
 - MUSC College of Dental Medicine