MUSC Bulletin | College of Graduate Studies
Molecular and Cellular Biology and Pathobiology Training Program
The goal of the Molecular and Cellular Biology and Pathobiology (MCBP) Training Program is to produce basic researchers who are qualified to pursue investigative careers and to become leaders in fundamental cellular and molecular biology. One of the major themes pf the program is the utilization of state of the art molecular approaches to obtain a better understanding of the disease process in man. The program offers opportunities for study and investigative work in many phases of cellular and molecular biology. Members of the faculty are engaged in a variety of interdisciplinary projects which include clinical applications as well as basic studies. The granting of the Ph.D. degree is based on evidence of general proficiency and of distinctive attainments in the field of cellular and molecular biology and pathobiology, particularly upon the demonstrated ability to carry on independent and original investigation.
The Molecular and Cellular Biology and Pathobiology training program includes over 140 faculty members who participate in one or more of seven inter-departmental doctoral research training tracks or divisions representing areas of significant interest in the basic biomedical and clinical sciences. The MCBP Divisions or program tracks of study are:
Cancer Biology - The Cancer Biology Division, an interdisciplinary program leading to a Ph.D. degree, was established in 2001 to provide students with training in diverse areas of cancer biology research. Cancer is a multi-step disease resulting from a series of genetic and epigenetic changes that abrogate normal cellular controls. The goal of the program is to develop within each student the approach to scientific thought founded upon basic molecular biology relevant to cancer needed for original research as an independent investigator in cancer biology.
The Cancer Biology Program is composed of MUSC faculty whose interests include basic studies in molecular biology, biochemistry, genetics, cell biology and immunology and translational research focused on problems of immediate clinical applicability. The Cancer Biology curriculum provides an overview of cancer biology and allows students the opportunity to pursue research under faculty mentors who conduct research relevant to understanding the molecular or cellular basis of any aspect of the cause, characteristics and treatment of cancer. Students are encouraged to use the resources and expertise of several laboratories during the development of their cancer-related dissertation projects, providing an enhanced experience that increases the expertise and competitiveness of our graduates. Successful students complete a publishable research project under a faculty mentor and present the research as a thesis.
Cardiovascular Biology - The Cardiovascular Biology Division is made up of over thirty faculty members from basic science and clinical departments with the goal of training students for careers as independent investigators studying the molecular and cellular aspects of cardiovascular physiology and disease. One of the medical triumphs of the latter half of the twentieth century is the remarkable advancement that has been made in the diagnosis and treatment of heart disease. Despite these advances, cardiovascular disease still remains the most common fatal and disabling disorder in the United States. Over the last two decades we have made tremendous progress in our understanding of the molecular aspects of biology. Now we have the opportunity to use these new and powerful molecular tools to explore complex biological systems, such as the heart.
The research focus of the Cardiovascular Biology Division is to find bold new approaches to aid our understanding, diagnosis and treatment of heart disease. Some areas of research interests in this program include gene regulation in heart development, differentiation and disease, regulation of cardiovascular function and metabolism, regulation of muscle contraction and protein turnover, and signal tranduction pathways in development and disease.
The Cardiovascular Biology Division is one of the divisions of the Molecular and Cellular Biology Program. Students who have satisfactorily completed the First Year Curriculum are qualified to enter the program. During their second and third year, students will complete at least 12 semester hours of advanced course work including Integrative Biology of the Cardiovascular System (MCBP-728) and the Molecular Basis of Cardiovascular Disease (MCBP-739), as well as other electives. These cover topics such as signal transduction, gene expression, genetic engineering and gene therapy, and genetics and development of the cardiovascular system. In addition, students will participate in the cardiovascular journal club.
Cell Regulation - Cell regulation refers to the process by which extracellular substances produce an intracellular response. This is a normal event by which hormones, neurotransmitters and other substances regulate cell function. In addition to these endogenous agents, many drugs and environmental compounds use these same mechanisms to produce their most important effects. Many research opportunities related to cell signaling mechanisms, including both basic signaling processes themselves and aberrant signaling mechanisms related to disease states, exist within this program. Indeed, many of the most recent breakthroughs in drug development stem from basic studies on signaling molecules.
Genetics & Development - The Division of Genetics and Development offers training and research in the field of genetics and developmental biology, which utilizes a variety of animal models to assess gene functions in embryonic development. Modern developmental genetics has become the central organizing field in all traditional disciplines in biology, such as cell biology, molecular biology, anatomy, evolution, and ecology. It has also contributed greatly to more practical fields such as medicine, environmental science and agriculture. The model systems studied by the faculty members include Drosophila (fruit fly) for oogenesis and vascular system development, zebrafish for environmental impact on embryogenesis, Xenopus (frog) for neurogenesis, chick for the formation of cardiovascular system, mice for a variety of organogenesis such as limb and follicle development, hematopoiesis, heart formation and mammary development, and human familial diseases for genetic linkage studies. In addition to transgenic and knockout technology, a variety of cell culture systems, including those for human stem cells, are utilized in the research.
Oral Health Sciences - The Department of Oral Health Sciences (formerly Department of Craniofacial Biology) was established in 2008 to unify the development of oral-related research in the College of Dental Medicine. Department of Oral Health Sciences research and educational activities are fully integrated with the multi- and interdisciplinary research community of the Medical University of South Carolina which includes the Colleges of Medicine, Dental Medicine, Pharmacy, Health Professions and Nursing.
The department's activities are further integrated with graduate training programs provided by the College of Graduate Studies and administered through The Molecular and Cellular Biology and Pathobiology Program.
All members of the Department of Oral Health Sciences have joint appointments in the basic science departments of the College of Medicine and/or the Department of Bioengineering with Clemson University. Most members of the department are members of the Hollings Cancer Center at the Medical University of South Carolina.
The research foci within the department includes:
- Molecular and cellular biology of periodontal inflammation and disease progression.
- Head and neck cancer cellular and molecular biology with focus on the signaling pathways involved in neoplastic development and progression.
- Bioengineering/Biomechanics of temporamandibular joint and craniofacial regeneration with emphasis on dentin regeneration.
- The role of microbial ecosystem in the epidemiology of inflammatory diseases in the oral cavity.
Marine Biomedicine & Environmental Sciences (MBES) - The MBES track provides training for the Ph.D. degree in numerous aspects of marine molecular biosciences that relate to environmental and human health. Key to the program is the active collaboration of our other on-site partner institutions, National Ocean Service (NOAA), Grice Marine Lab (College of Charleston), Marine Resources Research Institute (SC Department of Natural Resources), and the National Institutes of Standards and Technology. These institutions and MBES occupy a 90-acre campus at Ft. Johnson, site of the beginning of the Civil War. Together these institutions provide a rich collection of varied research mentors and training opportunities for MBES students in federal, state and academic institutions. In addition to separate laboratories on the same campus, these partner institutions occupy space in the newly-constructed Hollings Marine Laboratory, an 94,000 sq. ft. facility dedicated to molecular biology and structural chemistry of the marine environment.
The purpose of the MBES curriculum is to combine a solid background in molecular and cellular biology with flexible, individually-tailored programs in which students use cutting-edge molecular skills to solve environmentally relevant questions including those affecting human health. Thus students are prepared for future leadership roles in marine environmental and health-related sciences. Areas of focus within MBES include marine genomics, eco-genomics and marine molcular ecology, eco-toxicology, proteomics, bioinformatics, environmental carcinogenesis, marine natural products chemistry, marine biotoxins, marine mammal immunology, and structural biology (x-ray crystallography and nuclear magnetic resonance). New students begin their training in the first year curriculum taken by all matriculating doctoral students. The first-year curriculum involves comprehensive and integrated studies of biochemistry, molecular and cell biology with journal clubs, seminars, and workshops. The second year consists of specialized courses in which the principles of the first year are applied to focus topics such as Marine Genomics, Eco-genomics and Marine Molecular Ecology Proteomics, Bioinformatics, Biogeochemistry, Pollution Microbiology, Marine Natural Products Chemistry, and Molecular Immunity in Marine Animals. Students’ knowledge is then applied to "real world" environmental and human health problems through the MBES student’s doctoral research.
More detail on the MBES program can be found at http://musc.edu/mbes
The MCBP student in the structural biology track will obtain a solid foundation in macromolecular structure, biophysical methods, proteomics, and bioinformatics. Specific methods for structure elucidation include X-ray crystallography, nuclear magnetic resonance, and mass spectrometry. Macromolecular structure/function relationships as they relate to disease processes and therapies will also be studied.
Selection of Graduate Advisory Committee
After the student has chosen an advisor, he/she will form an advisory graduate committee with the help of his/her advisor of at least four other members of the graduate faculty. The advisory committee needs to be organized no later than November of the second year. The advisory committee will provide guidance and monitor progress during the remainder of the student's Ph.D. program. Students are required to have their first committee meeting by December of their second year. At this meeting, students should present a brief outline of the specific aims of their proposed research. You are required to meet with your committee once a year.
Advanced Course Work
Students are required to take 12 units of advanced course work beyond the common first year curriculum. Students can take any course offered in any of the MCBP Divisions. In addition, students may take advanced courses offered by any of the other departments in the graduate program at MUSC.
Predoctoral students must enroll for 15 hours each semester. Students can elect to take their advanced courses during their second year or to spread them out into their third year as well. It is expected that the majority of the student's time from the second year on will be devoted to research.
MCBP Seminar Series (MCBP 724)
Students must register for Seminar, MCPB 724, every semester while in the program. The Thursday 4:00 pm MCBP External Seminar Series invites leading scientists from the United States and foreign countries to present their work to both students and faculty in the MCBP Program. These seminars are on a broad range of topics representing each of the six divisions within the MCBP Program. Importantly, students have the opportunity to meet informally with the speakers over lunch. Students must attend two thirds of the Thursday Seminars during the semester. Excused absences must be approved by the MCBP Seminar Series Director.
Select a Journal Club
At the beginning of the second year with the help of their mentor, students will pick a division in the MCBP program. Each Division offers track-specific advanced courses as well as one or more journal clubs. Students must register for one of the Journal Clubs offered each semester. Attending Journal Clubs from other graduate programs is allowed with the approval from the MCBP Director.
Written Qualifying Examination
The MCBP written Qualifying Examination is administered once a year in June. The students will have one week to answer one long answer question and three short answer questions. The objectives of the examination are to determine if the student understands the principles of cell and molecular biology, are able to read and comprehend relevant literature related to the question, and can synthesize a coherent and well-written response.
When the student has passed the written examination, a summary of the strengths and weaknesses of the student's performance will be compiled and forwarded to the student's dissertation committee, along with the student's graded examination questions. A critique of the student's performance on each exam question will be provided to the student. If a student fails a single examination question, he/she has the opportunity to retake the question within 2 weeks of receiving their grade for the examination. If a student fails the entire exam, the student must petition the MCBP Examination Committee to be allowed to retake the examination the following June. The student's progress in the program, performance on the exam, and letter from the student's advisors will be important factors in determining if the student will be permitted to retake the examination. If the examination is failed after a second attempt, the student will be dismissed from the MCBP Doctoral Program.
Oral Qualifying Examination
The oral qualifying examination must be taken within 8 months of successfully passing the written qualifying examination. The student will submit the SPECIFIC AIMS page of his/her research proposal to his/her graduate committee at least 7 days before the oral examination. The examination committee consists of the student's dissertation committee, (but not the student's mentor) and is chaired by a senior MCBP faculty member appointed by the MCBP Director. The examination will consist of general questions to test the student's background, questions related to areas covered on the student's written examination, and general questions focused on the student's proposal Specific Aims. The objectives of the oral examination are to test the ability of the student to think on his or her feet, test the student's general knowledge of cellular and molecular biology, knowledge of his/her area of research and to examine weaknesses in the student's knowledge base that were identified in the written examination.
Within 6 months of successfully passing his or her oral qualifying examination, the student will submit a research proposal in NIH format on his or her research topic. The length of the research proposal is suggested to be between 5 and 8 pages. It must be submitted to each member of the thesis committee at least 1 week before the student's committee meeting. The student will orally present his/her proposal to the committee in a 30-minute seminar. The student's committee will evaluate the proposal and the student must make all changes to the written proposal recommended by the committee. The committee must approve the research proposal, but this committee meeting is not part of the oral examination, and committee members may be helpful in advising the student on experimental strategies or alternative approaches in the aims proposed by the student.
Dissertation in Seminar & Defense
During the fourth and subsequent years of graduate study, students are primarily responsible for conducting their research project and meeting with their committee at least once a year. A dissertation based on original investigation is required which gives evidence of mature scholarship and critical judgment, indicates knowledge of research methods techniques and demonstrates the ability to carry out independent investigation. After your mentor has approved your written dissertation, it should be submitted to each of your graduate committee members. The graduate committee requires 7-14 days to review your dissertation before they sign the dissertation notice certifying that it is ready to defend. The Dissertation Defense Notice needs to be turned in to the graduate office at least 3 weeks before the scheduled public defense.
Publication of doctoral dissertations is required of all students. The dissertation committee will not sign the Dissertation Defense Notice form until the candidate has a first author manuscript accepted for publication. Each candidate must present his/her Dissertation in a public seminar. Following this formal presentation of approximately 50 minutes, general questions are taken from the audience, which includes student and faculty members of the MCBP program as well as general faculty. After general questions, a closed-door examination is conducted by the student's dissertation committee and graduate faculty. The dissertation committee will have the primary responsibility for evaluating the student's research, including the written dissertation, the formal oral presentation, and for administrating the final oral examination. Approval of the advisory committee with no more than one dissenting vote is necessary for recommendation for awarding the degree. In the event of disapproval by the committee, the candidate may be permitted to retake the final oral examination in not less than six months and not more than two years from the time that this decision was made. Only one opportunity for re-examination is given.
Faculty Research Interests
Cancer Biology Faculty Research Interests
Faculty research interests can be found on the web at http://academicdepartments.musc.edu/grad/departments/mcbp/concentrations/cancer_biology/
Cardiovascular Biology Faculty Research Interests
Faculty research interests can be found on the web at http://academicdepartments.musc.edu/grad/departments/mcbp/concentrations/cardiovascular_biology/
Cell Regulation Faculty Research Interests
Faculty research interests can be found on the web at http://academicdepartments.musc.edu/grad/departments/mcbp/concentrations/cell_regulation/
Genetics and Development Faculty Research Interests
Faculty research interests can be found on the web at http://academicdepartments.musc.edu/grad/departments/mcbp/concentrations/genetics_development/
Marine Biomedicine and Environmental Sciences Faculty and Research Interests
Faculty research interests can be found on the web at http://academicdepartments.musc.edu/mbes/
Oral Health Science Faculty Research Interests
Faculty research interests can be found on the web at http://academicdepartments.musc.edu/ohs/
Required Core Course Descriptions
Students are required to take at least 12 units of advanced course work beyond the common first year curriculum. Students can take any course offered in any of the MCBP Divisions. Students are recommended to take two (three unit) courses in their chosen MCBP division and any two (three unit) courses outside of their Division. Selection of courses should be made with your mentor and with the approval of your graduate committee. Students may also take courses offered by any of the other departments in the graduate program at MUSC. In addition students in the MCBP Program are required to register for MCBP-724 Seminar in Molecular and Cellular Biology and Pathobiology every semester from their second year to the date of their Final Defense.
MCBP-724. Seminar in Molecular and Cellular Biology and Pathobiology. Thursday MCBP Seminar Series. The Thursday 4:00 pm MCBP External Seminar Series invites leading scientists from the United States and foreign countries to present their work to both students and faculty in the MCBP Program. These seminars are on a broad range of topics representing each of the six divisions within the MCBP Program. Importantly, students have the opportunity to meet informally with the speakers over lunch. 1 s.h. Fall/Spring
Advanced Courses in the MCBP Program Listed by Division
Most courses are offered every other year. Please note that some courses are offered in multiple divisions.
Cancer Biology and Cell Regulation Division
MCBP-725D. Topics in Cancer Research. Two presentation formats will be used for the course. Initially, a faculty member will introduce and direct all students in the discussion of selected literature concerning a single topic. Subsequent topics will be presented by individual students in Journal Club style. Each student will have two opportunities to present selected topics during the course and will be active discussants when other students present. Topics to be covered include:
Oncogenes and Tumor Suppressor Genes
Cell Proliferation and Cycle Control
Oncogenes and Tumor Suppressor Genes
Signal Transduction and Growth Regulation
Transgenic and Knockout Models
Prerequisites: None. Fall Offering. 3 s.h. (Pass/Fail)
MCBP-750. Otolaryng & Comm Hlth Seminar. Otolaryngology and Communication Health Seminar Series brings premier scientists in areas related to otolaryngology and communication health to MUSC to give seminars and meet with trainees and program faculty. Seminars are scheduled monthly during the academic year, on an alternating two-week schedule with Otolaryngology and Communication Health Journal Club. The Seminar Series is an interactive venue with an expanding network of visitors to the MUSC campus. Some vistors present talks on topics directly related to otolaryngology or communication disorders while others discuss topics of more general interest to basic and clinical trainees and faculty, including genetics, proteomics, health outcomes, and computational biology. Seminars may also be focused on emerging technologies/techniques, such as advanced microscopy and imaging, microarray technology, and optogenetics. Trainees meet individually or as a group with the invited speakers.
MCBP-751. Otolaryng & Comm Hlth Journal Club. Club meets monthly during the academic year, on an alternating two-week schedule with Otolaryngology and Communication Health Seminar Series. Hosted by the Department of Otolaryngology-Head and Neck Surgery and directed by selected Core Mentors, Journal Club disseminates recent otolaryngology and communication health-related publications and provides a supportive environment to discuss research evidence and implications for clinical outcomes and treatment. Presentations are by students, postdoctoral fellows, and faculty; Journal Club is open to all individuals interested in the topics under discussion, including laboratory staff. While the primary motivation is promotion of scientific discussion, Journal Club also provides an opportunity for social and collaborative networking.
MCBP-752. Basic Receptor-ECM Signaling. This course will present the general concept of predominant cell signaling events in inflammatory pathology and developmental biology. Students in most programs use cell signaling as part of their research. This course will cover the power of signaling that influences the fate of the cells, development of the organ, and therapeutic strategies in inflammatory pathology and cardiac development. Prerequisite: Biology or Biochemistry. 3.0 s.h. Spring
MCBP-780. Vision & Ocular Diseases. Current and emerging topics in vision and ocular diseases will be presented and discussed in a journal club-style format. Students will present topics related to vision and ocular diseases using faculty-approved articles from peer-reviewed journals, and will be expected to actively participate in the discussion with other students, post doctoral fellows, and faculty members. Some presentation will be made by visiting and MUSC faculty members. 1.0 s.h. Fall/Spring.
MCBP-801. MCBP of Mineralized Tissues. This course will cover the biologic principles and cellular/molecular processes of mineralized tissue development, composition and regulation in health and disease. The objectives of this course are: 1) To further understanding of the biologic principles of mineralized tissue development, composition and regulation in health and disease. 2) To develop the ability to read and critique literature in the mineralized tissue field that pertains to craniofacial biology. 3) To achieve a high level of expertise in at least one topic area of mineralized tissues via presentation for education and peer review.
Cardiovascular Biology Division
MCBP-728. Integrative Biology of the Cardiovascular System. This course is designed to build on the Receptors and Signaling and Systems Biology units of the first year curriculum for Ph.D. students to provide the students with an in depth understanding of the structure, function and integration of the cardiovascular system at the human and whole animal levels and the assessment of cardiovascular function in whole animal models including transgenic animals. Current concepts of the cell and molecular biology bases of cardiovascular function, dysfunction and responsiveness to therapeutic interventions will be explored. Course faculty include investigators from Adult Cardiology, Adult Endocrinology, Cell Biology and Anatomy, Pharmacology, Physiology and Neuroscience and Surgery. Relevant material will be addressed through a combination of lectures, discussion of papers from the literature and problem solving exercises (open book). 3 s.h. Offered in Fall Semester of alternate years.
MCBP-739. The Molecular Basis of Cardiovascular Disease. The course is designed to highlight the advances in cardiovascular science and medicine, which will soon form the foundation for novel diagnostic, prognostic and therapeutic approaches to treating heart disease. Over the past decade a growing number of genes, receptors, channels and signaling factors have been shown to play a role in cardiovascular disorders. The course will examine the new approaches and technology that are being utilized to identify the molecular mechanism that these factors play in cardiovascular function and disease. We will discuss the power of utilizing molecular genetics to unravel heart diseases. We will also look at advances in our understanding of cardiovascular development, and electrophysiology. We will also discuss how new breakthroughs in tissue engineering may allow for the replacement of diseased myocardium. The course will also include sections on vascular biology and atherogenesis. This Course will be taught every other year in the spring. 3 s.h. Offered in Fall Semester of alternate years.
MCBP-782. Cardio Biology Journal Club. The Cardiovascular Biology Journal Club course is designed to highlight the advances in cardiovascular science and medicine that will soon form the foundation for novel diagnostic, prognostic and therapeutic approaches to treating heart disease. Publications will be presented by the students weekly, which address current concepts of the cell and molecular biology bases of cardiovascular function, dysfunction and responsiveness to therapeutic interventions. Students, postdoctoral fellows and faculty who will take part in the weekly discussion include investigators from adult cardiology, adult Endocrinology, Cell Biology and Anatomy, Pharmacolgy, and Surgery. 1.0 s.h. Fall/Spring.
Genetics and Development Division
MCBP-743. Cellular Signaling Development. This course is designed to build on the Regulation of Gene Expression, Biomembranes, Receptors and Signaling and Systems Biology units of the first year curriculum for Ph.D and complement ongoing Department-specific seminars and journal clubs. Cellular Signaling during development will provide the students with an indepth look at ongoing research in the field of developmental biology with a strong focus on the signaling networks that control these important processes. It will allow for a broad scope of understanding of the techniques, theories and practices involved in the delineation of cellular signaling in complex systems. 3 cr. hr., spring
MCBP 762. Mechanisms of Development. This course will provide a general overview of fundamental developmental mechanisims focused on a comparison of different model organisms. This course covers early and intermediate developmental events (gastrulation and cardiovascular), and perinatal maturation through induction of stem-ness in differentiated adult cells. Comparative systems discussed include fly, zebrafish, Xenopus, chick, and mouse models. The course is intended for graduate students training in any aspect of biomedical research. 3.0 s.h.
Oral Health Sciences Division
OHS-745. Topics In Oral Health Science. Current and emerging topics in oral health science will be presented and discussed in a journal club style format. Initially, a faculty member will introduce and direct all students in the discussion of literature concerning oral-related research topics. Subsequently, students ill preent topics using faculty-approved papers from top-tiered journals. Students will be expected to participate in active class discussion with other graduate students, postdoctoral fellows, and faculty.
OHS-747. Oral Health Sciences Seminar Series. In this series, students give a seminar based on their own research to their fellow students, advisory committee, faculty and post-doctoral fellows in the College of Dental Medicine. This is a great opportunity for the students to present their work in an informal setting and to receive constructive feedback on his/her studies from a large audience with different scientific backgrounds. Each graduate student will give at least one seminar yearly. Lectures will be supplemented with local as well as invited external speakers, whose research focus is on oral health sciences.
Marine Biomedicine & Environmental Science Division
MCBP 725P. St: Environment, Impacts on Human & Ocean Health. This course introduces students to some of the topical issues in marine and environmental Sciences as they relate to Human Health. The course shows the application of cell and molecular biology and epidemiology approaches to environmentally relevant questions that ultimately impact human health. These topics are put into context of the reports of the International Panel on Climate Change, the Kyoto Protocol, and the latest Bali summit. In addition students will participate in learning how results from research in environmental cell and molecular science are synthesized with economics and law to form public policy. The role of federal and SC state government agencies in these processes will be presented through the appropriate representatives of these agencies on the Ft. Johnson campus. This is a course that includes students reading scientific papers, lay communications, and books in conjunction with active class participation through discussions on topical issues. 3 s.h, spring Louis J. Guillette, Jr.
MCBP 746. Environment, Oceans & Humans. This course introduces the concept of environmental endocrine disrupting chemicals on human and wildlife health. We discuss topics in the fields of environmental health, ecotoxicology and try to understand the complex underlying biological mechanisms associated with these processes. Students will be required to read chapters from a textbook as well as basic science articles from the popular or scientific literature. 3 s.h, spring Satomi Kohno
MCBP 749. Marine Organ Health. Current and emerging topics in marine organismal and environmental health will be presented and discussed in a journal club-style format. Students will be present topics related to the topic of marine organismal and environmental health using faculty-approved articles from peer-reviewed journals, and will be expected to actively participate in the discussion with other students, post doctoral fellows and faculty members.
Cell Biology and Anatomy Course Descriptions
The number of semester hours is designated by s.h.
CELL-621G. Dental Gross Anatomy and Neuroanatomy. Emphasizes normal human gross anatomy. All regions of the body are dissected except the perineum and lower extremity. Special emphasis is given to the head, neck, and thorax. The material is presented in a number of ways: by regional dissection, by study of normal radiograms, by lectures, by outside readings, and by textbook assignments. 9 s.h. Summer.
CELL-662G. Dental Histology and Embryology. Develops knowledge of (a) the structure and function of cell organelles and the histological features of the organization of cells into the four fundamental tissues, (b) the microanatomy of the integument, oral cavity, and all organs of the body, and (c) the development of the embryo from fertilization through the formation of organ systems. Special emphasis is given to the oral cavity, the special histology and development of the tooth, and the development of the head and neck. This course is primarily intended for dental students, although it is suitable for graduate students and certain health related professions students who have a college-equivalent education. Prerequisite: permission of instructor. 8.5 s.h. Fall.
CELL-760. Cell Biology Seminar. Seminars in which oral presentations upon a topic are given by the graduate students enrolled. This is offered twice per year, and the faculty member in charge as well as the general topic vary. The student is evaluated primarily on his/her class presentation; the evaluation is based on organization, accuracy, and thoroughness of presentation. 1 s.h. All.
CELL-762. Topics in Developmental Biology. Introduces primary literature from areas of current research in developmental biology. Topics to be covered include the origin of cell lineages, control of cell differentiation, gene regulation of embryonic patterning, cell-cell and cell-matrix interactions, and programmed cell death. This course is intended for graduate students. Prerequisite: permission of instructor. 2 s.h. Spring.
CELL-764. Topics in Cell Biology. Specific subdisciplines in cell biology are reviewed in-depth. The current literature in the field is read and carefully critiqued by the students and presented by them for discussion. Possible alternatives in interpretation of data are offered, as well as the design of experiments which would help to clarify the research problem. 1-4 s.h. Spring.
CELL-770. Special Projects in Cell Biology. Individual Regenerative Medicine and Cell Biology and Anatomy staff members guide limited numbers of students in the pursuit of new knowledge. Intended for those students desiring research experience in the topics of current interest in anatomy, but open to those who would pursue relevant and realistic projects of their own design. Prerequisite: permission of instructor. 1-9 s.h. All.
|Last Published with Edits:||October 13, 2015 3:24 PM|
|Last Comprehensive Review:||August 2014|