MUSC Bulletin | College of Graduate Studies
Pathology and Laboratory Medicine
Of all the medical sciences, pathology most closely bridges the gap between clinical medicine and the basic sciences. The Department of Pathology and Laboratory Medicine offers advanced study leading to a Ph.D. degree in Experimental Pathology and Laboratory Medicine. The objectives of this program are to provide an in-depth understanding of molecular and cellular mechanisms of human disease processes, and to provide the skills and critical thinking required to perform scientific research. Clinical and basic scientists interact within the department in the study of disease processes, with research emphasis on: progression and treatment of cancer, gene expression in cancer and disease and pathogenesis and molecular biology of hearing loss. The latest biochemical, molecular and cellular techniques are being used to resolve these research problems.
The Department of Pathology and Laboratory Medicine is composed of four divisions: anatomic pathology, laboratory medicine, research pathology and pathology education. The department employs 52 full-time faculty and is responsible for the operation of diagnostic laboratories in surgical pathology, autopsy pathology, forensic pathology, molecular pathology, cytology, cytogenetics, immunopathology, hematology, transplantation and transfusion medicine, diagnostic immunology, clinical chemistry and clinical microbiology. The combination of the clinical and basic sciences in the department keeps students in close touch with current medical problems as they initiate and perform their research.
Research facilities available in the Department of Pathology and Laboratory Medicine reflect the diversity of the department. Research laboratories and the pathology education division are located in the Walton Research Building and other buildings across campus, with anatomic pathology and laboratory medicine facilities located in the Children’s Hospital. Major equipment and facilities include: molecular biology facilities, protein purification and analysis equipment, transmission and scanning electron microscopy, tissue culture and tissue bank facilities, histopathology facilities, image processing and analysis facilities including laser scanning confocal microscopy, microscopy fluorometry, single-cell microinjection, and timelapse video imaging.
Students acquire a broad education in the medical sciences in course work taken during the first two years of the program. The first year of the curriculum consists of the Core Curriculum offered by the College of Graduate Studies. Students also gain experience in scientific methodology in the first year by rotating through research labs throughout the University. At the end of the first year, students in the Pathology program take a Selective course in Histology that provides an understanding of the microscopic architecture of the human/animal body. The General Histology course is a prerequisite for the General & Systemic Pathology course that is taken in the second year. The general pathology course is designed to provide students with an understanding of basic mechanisms of disease.
Students begin formal seminar presentations in their second year, and these are repeated annually until graduation. An understanding of research problem-solving is gained as students define, develop and complete an independent research project under the mentorship of a member of the Graduate Faculty in the department. An advisory committee, selected by the student and their mentor, also helps to guide the student to successful completion of their proposed research.
|Last Published with Edits:||July 29, 2016 11:26 AM|
|Last Comprehensive Review:||July 2015|