Charles Smith, Ph.D.
Professor of Pharmaceutical Sciences, MUSC
South Carolina Center of Economic Excellence Endowed Chair
Dr. Smith completed his Ph.D. at Michigan State University, and has held appointments at Duke University, the University of Hawaii, the Fox Chase Cancer Center, and Pennsylvania State University. He is currently a Professor of Pharmaceutical Sciences at MUSC, holds a South Carolina Center of Economic Excellence Endowed Chair, and also serves as the Director of the Drug Discovery Core Facility at MUSC.
Dr. Smith's research interests center on drug discovery and cancer pharmacology. His projects relate to signaling systems involved in tumor growth, and have been continuously supported by multiple grants from the NIH and other sources for nearly 20 years. He has more than 80 research publications, and multiple US and international patents.
Dr. Smith is the Founder of Apogee Biotechnology Corporation, an early-stage drug discovery company focused on the development of proprietary compounds for the treatment of cancer and inflammatory diseases. Apogee has been funded by many SBIR grants from the National Institutes of Health (~$7.5M to date), and controls a portfolio of issued and pending US and PCT patents relating to sphingosine kinase inhibitors and their uses. The lead compound in this program is currently in GLP toxicology studies in anticipation of an IND application in early 2009.