College of Graduate Studies
Cancer Biology Course Descriptions
MCBP-725D Topics in Cancer Research
Selected topics will be presented by individual students in Journal Club style. Students will present selected papers 2 times during the course and will be active discussants when other students are presenting.
Recent topics previously covered include:
Tumor metastasis Suppressor Genes
Bone marrow derived cells
Credits: 3 (Pass/Fail)
Rosenzweig and Watson
PCOL-725 Advanced topics in Cell Signaling
The vast majority of human diseases involve defects in cellular communication and therapeutic intervention often targets molecules involved in cell signaling. This course will dissect signaling cascades and their alterations in disease states addressing cutting edge issues. The course will be offered each Fall with the theme rotating among three broad topics: Cell Signaling in the Cardiovascular System, Cell Signaling in Cancer, Cell Signaling in the Nervous System. Specific diseases under these broader categories will be selected by faculty or students and then each disease will be dissected by one of the course participants (oral/written) to understand how signaling events are affected, how signaling dysfunction contributes to the onset or progression of the disease and how signaling events might be targeted in a therapeutic attack on the disease. The course is intended for advanced graduate and postgraduate students and will be coordinated with the Cell-Signaling Seminar Series (organized through the Department of Pharmacology) held each Fall, thus allowing seminar speakers to participate in the course.
BMB-605B Mechanisms of Cancer Pathogenesis
Dr. Tilman Heise
MBIM 716 Development of Molecular Cancer Therapies: From Bench to Bedside
This course is organized into 7 sections (1) Introduction to cancer causation, initiation, molecular basis, and genetics; (2) Cancer molecular pathology and diagnosis; (3) Cancer imaging; (4) Immunology of cancer; (5) Drug therapy; (6) Cancer epidemiology, prevention and control; (7) Translational reserch
Tew and Norris
MCBP 748/BMB 748 Lipids in Pathobiology
This multidisciplinary course addresses biochemical, applied, and translational approaches to the study of lipids. The course is composed of three main sections: lipid biosynthesis, lipid signaling, and lipids and disease. The first section is a comprehensive treatment of nomenclature and synthesis of major lipid classes including glycerophospholipids, sphingolipids, and sterols, as well as methodology for lipid study. The second section addresses roles of bioactive members of these lipid classes in regulation of cell signaling and downstream events. The third section is largely translational, with many lectures on human diseases that involve the lipids and signaling pathways discussed. This course contains a brief hands-on laboratory segment. This course is open this to graduate students, residents, postdocs, and third and fourth medical students.
Director: Samar M. Hammad (Co-Director: Ashley Cowart)
Offered every two years in the Spring
PATH-792 Anatomy, Histology and Histopathology of the Laboratory Mouse
This course is offered as an elective course during the first three weeks of the summer semester. The anatomy, histology, and histopathology of the laboratory mouse will be presented. Emphasis will be placed on differences between human and mouse so future investigators who may use a mouse model of human disease will understand approaches to developing new modes as well as limitations of a given model. Lectures will present anatomy, histology, basic principles of pathobiology and unique mouse pathology. Lab sessions will be used to demonstrate the proper way to perform a pathological examination on properly euthanized animals. Tutorials using glass and virtual slides will be included. Students will learn and execute a necropsy (term for post-mortem examination in veterinary medicine) of the mouse. Two Genetically Engineered Mouse (GEM) models will be introduced by Drs. Awgulewitsch and Spyropoulos at the end of the course to reinforce the significance of understanding differences between mouse and human anatomy, histology, and pathology. Due to the brevity of the course, only a limited number of pathological entities will be included. 3 credit hours. Prerequisite: PATH 789, Graduate Histology: Introduction to Pathology, or CELL 609: Medical Histology, or by permission of the course directors.
Robert W. Olilvie, Ph.D. (firstname.lastname@example.org), Kristi L. Helke, DVM, Ph.D. (email@example.com)
Cancer Biology Faculty
Alexander Awgulewitsch, Ph.D.
Craig Beeson, Ph.D.
Narayan R. Bhat, Ph.D.
David J. Cole, M.D.
Stephen Ethier, Ph.D.
Weiman Fan, M.D., M.P.H.
Sebastiano Gattoni-Celli, M.D.
Monika Gooz, M.D., Ph.D.
Stanley R. Hoffman, Ph.D.
Philip H. Howe, Ph.D.
Michael Kern, Ph.D.
Keith Kirkwood, Ph.D.
Dhandapani Kuppuswamy, Ph.D.
Anna-Liisa Nieminen, Ph.D.
James S. Norris, Ph.D.
Chandrakala Puligilla, Ph.D.
Mark Rubinstein, Ph.D.
Stephen Tomlinson, Ph.D.
Christina Voelkel-Johnson, Ph.D.
Dennis K. Watson, Ph.D.
Elizabeth Yeh, Ph.D.
M. Rita I. Young, Ph.D.