College of Graduate Studies

MCBP Past Seminars

This is a collection of past seminars held by the MCBP Program.

Thursday External Seminar Series Calendar
Room 125 - Gazes Conference Room - 4:00 pm
Gazes Cardiac Research Institute/Strom Thurmond Building

FALL 2012 (pdf)

Spring 2012
January 12, 2012	William Kaufmann, PhD Professor of Pathology and Laboratory Medicine University of North Carolina Chapel Hill, North Carolina Title: "The Replication Fork Protection Complex Stabilizes Human Chromosomes"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
January 19, 2012	No Seminar
January 26, 2012	Yves A. DeClerck, MD Professor Keck School of Medicine The Saban Research Institute Childrens Hospital University of Southern California Los Angeles, California Title: “Cancer is not only a disease of the genes: Contribution of bone marrow-derived cells to neuroblastoma progression"	Host: Dr. Dennis Watson Sponsor: MCBP
February 2, 2012	Stephen White, DPhil Member and Chair Department of Structural Biology St. Jude Children’s Research Hospital Memphis, Tennessee Title: “Old Foes, New Therapies: Influenza and Bacterial Pathogens”	Host: Dr. Chris Davies Sponsor: Biochemistry
March 1, 2012	No Seminar
March 8, 2012	Alan G. Hinnebusch, PhD Head, Program in Cellular Regulation and Development Chief, Lab of Gene Regulation and Development National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development Bethesda, Maryland Title: “Mechanism of Ribosomal Scanning and AUG Selection in Translation: Where to Begin?”	Host: Dr. Tilman Heise Sponsor: Biochemistry
March 15, 2012	Hani N. Sabbah, PhD, FACC, FCCP, FAHA Professor of Medicine & Director of Cardiovascular Research Henry Ford Health System Henry Ford Hospital Detroit Michigan Title: "The Heart-Brain Corridor: A New Approach for Treating Heart Failure"	Host: Dr. Rupak Mukherjee Sponsor: MCBP
March 22, 2012	Speaker: TBA
March 29, 2012	Francesco Marincola, MD Chief, Infectious Disease and Immunogenetics Section (IDIS) Department of Transfusion Medicine at the Clinical Center Nathional Institutes of Health Bethesda, Maryland Title: “The Emerging Fruits of a Decade of Discovery-Driven Immune Monitoring”	Host: Drs. Paul McDermott and Sebastiano Gattoni-Celli Sponsor: MCBP
April 5, 2012	Rolf Brekken, PhD Associate Professor of Surgery and Pharmacology UT Southwestern Medical Center Dallas, Texas Title: "Uncovering Pathways Driving Hypoxia Induced Tumor Progression: The Importance of ECM and EMT"	Host: Dr. Amy Bradshaw Sponsor: MCBP
April 12, 2012	Speaker: TBA
April 19, 2012	John M. Denu, PhD Director, Epigenetics Theme Wisconsin Institute for Discovery Professor, Department of Biomolecular Chemistry University of Wisconsin Madison, Wisconsin Title: "Chemical and Biological Functions of Sirtuins"	Host: Dr. Donald Menick Sponsor: MCBP
April 25, 2012	Classes End
April 26, 2012	Speaker: TBA
May 3, 2012	Speaker: TBA
May 10, 2012	Wolfgang Peti, PhD Associate Professor of Medical Science Associate Professor of Chemistry Department of Molecular Pharmacology, Physiology & Biotechnology Brown University Providence, Rhode Island Title: "Understanding the specificity of ser/thr kinases and phosphatases"	Host: Dr. Mirko Hennig Sponsor: Biochemistry
Fall 2011
Sept 1, 2011	No Seminar
Sept 8, 2011	Maurizio Del Poeta, Ph.D. Medical University of South Carolina Department of Biochemistry & Molecular Biology Title: “Role of Sphingolipids in Mocrobial Infection	Sponsor: Biochemistry
Sept 15, 2011	Cynthia Kenyon, Ph.D. University of California, San Francisco Director of the Hillblom Center for the Biology of Aging Title: "Cells and Pathways that Control the Aging of C.elegans"	Host: Dr. Baerbel Rohrer Sponsor: MUSC Woman Scholars Initative
Sept 22, 2011	Yibin Wang, Ph.D. Vice Chair for Research at Anesthesiology Director of Division of Molecular Medicine Professor of Anesthesiology, Physiology and Medicine University of California, Los Angeles Title: "In Pursuit of a Perfect Heart: From Molecules to Systems"	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
Sept 29, 2011	Charles O. Rock, Ph.D. St. Jude Children's Research Hospital Department of Infectious Diseases Title: “Bacterial Lipid Synthesis: Unique Biochemistry and Antibacterial Drug Discovery”	Host: Dr. Yong-Mei Zhang Sponsor: Biochemistry
October 6	Robert Bambara, Ph.D. University of Rochester Professor of Biochemistry and Biophysics Title: "Evidence that Acetylation Regulates DNA Replication to be More Accurate in Actively Transcribed Chromatin"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
October 13, 2011	Litsa Kranias, Ph.D. University of Cincinnati Director of Pharmacology & Cell Biophysics Title: “Calcium Circuits in the Heart: A Matter of Life and Death"	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular
October 20, 2011	Philip H. Howe, Ph.D. Associate Director of Basic Sciences Professor of Biochemistry & Molecular Biology Title: “Transforming growth factor beta (TGFbeta)-mediated epithelial-mesenchymal transitions (EMT)”	Sponsor: Biochemistry Medical University of SC, Hollings Cancer Center
October 27, 2011	Timothy A. McKinsey, Ph.D. University of Colorado Associate Professor Division of Cardiology Title: “Targeting Histone Deacetylases for Heart Failure”	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
November 10, 2011	Perry V. Halushka, M.D., Ph.D. Medical University of South Carolina Dean, College of Graduate Studies Professor of Pharmacology & Medicine Title: “College of Graduate Studies – Town Hall”
November 17, 2011	Raja Fayad, MD Department of Exercise Science Arnold School of Public Health Title: “Adiponectin Deficiency: Role in chronic inflammation induced colon Cancer”	Host: Dr. Titus A. Reave Sponsor: MCBP University of South Carolina
December 1, 2011	George Kunos, M.D., Ph.D., FAHA National Institutes of Health (NIH) Scientific Director National Institute on Alcohol Abuse and Alcoholism (NIAAA)	Host: Dr. Yusuf Hannun Sponsor: Biochemistry
December 8, 2011	Dr. Junichi Sadoshima M.D., Ph.D. University of Medicine & Dentistry of New Jersey Professor, Cell Biology & Molecular Medicine Title: “Redox regulation of growth and death in cardiomyocytes"	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
December 15, 2011	Michael R. Botchan, Ph.D. University of California, Berkeley Professor of Biochemistry and Molecular Biology Title: "Starting and stopping S phase- unwinding DNA"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
Spring 2011
January 6, 2011	Randy R. Brutkiewicz, Ph.D. Professor and Assistant Dean of Faculty Affairs and Professional Development Indiana University School of Medicine Title: “Regulation of Antigen Presentation by Cell Signaling Pathway”	Host: Dr. Azizul Hague Sponsor: Biochemistry
January 13, 2011	No Seminar	Host: Sponsor: Biochemistry
January 20, 2011	Gustavo W. Leone, Ph.D. Associate Professor, Molecular Virolgy, Immunology, & Medical Genetics Human Cancer Genetics Program Ohio State University, College of Medicine Title: “PTEN & p53 in the Tumor Microenvironment: Out in the Neighborhood”	Host: Dr. Ogretmen Sponsor: Biochemistry
January 27, 2011	Seminar Cancelled
February 3, 2011	Seminar Cancelled
February 10, 2011	Richard A. Cerione, Ph.D. Professor of Pharmacology Department of Molecular Medicine College of Veterinary Medicine, Cornell University Title: "Cdc42: Some New and Unexpected Discoveries"	Host: Dr.Yusuf Hannun Sponsor: Biochemistry
February 17, 2011	Federico Gonzalez-Fernandez, M.D., Ph.D. Professor of Ophthalmology & Pathology Ross Eye Institute, State University of NY Title: “Interphotoreceptor retinoid-binding protein (IRBP) - an old gene for new eyes”	Host: Dr. Yiannis Koutalos Sponsor: MCBP
February 24, 2011	Jia L. Zhuo, MD, PhD Professor of Pharmacology and Medicine Laboratory of Receptor and Signal Transduction Department of Pharmacology & Toxicology Division of Nephrology Department of Internal Medicine The University of Mississippi Medical Center Title: “Intracrine Renin-antiotensin System: A New Paradigm in Cardiovascular and Renal Control”	Host: Drs. Fitzgibbon and Morinelli Sponsor: MCBP
March 3, 2011	Charlie Boone, Ph.D. Professor Banting and Best Department of Medical Research University of Toronto Toronto, Canada Title: “The Genetic Landscape of a Cell”	Host: Dr. Ashley Cowart Sponsor: Biochemistry
March 10, 2011	Eva M. Mezey, M.D., Ph.D. NIH, NIDCR Bethesda, MD Title: "Immunosupression by bone marrow derived stromal cells"	Host: Dr. Monika Gooz Sponsor: MCBP
March 17, 2011	Webster Cavenee, Ph.D. Professor of Medicine and Cell & Molecular Medicine Cancer Biology Program Director, Ludwig Institute for Cancer Research University of California, San Diego Title: “Cell Intrinsic and Extrinsic Effects of Cell Signaling: Implications for Tumor Population Dynamics"	Host: Dr. Dennis Watson Sponsor: MCBP
March 24, 2011	Dr. Natasha Kyprianou James F. Hardymon Chair of Urology Research Professor of Surgery/Urology Professor of Molecular and Cellular Biochemistry Professor of Pathology and Laboratory Medicine Title: “TGF-beta Signaling in Prostate Cancer”	Host: Drs. Jim Norris/Christina Voelkel-Johnson Sponsor: Micro and Immunol
March 31, 2011	Matthew (Mengsheng) Qiu, Ph.D. Professor & Distinguished Scholar Anatomical Sciences & Neurobiology University of Louisville Title: "Origin and molecular specification of oligodendrocytes in the Spinal Cord”	Host: Narayan Bhat Sponsor: MCBP
April 7, 2011	Seminar Cancelled	Host: Sponsor: Biochemistry
April 14, 2011	Rima Rosen, Ph.D. Professor, Department of Human Genetics, Vice Principal for Research & International Relations McGill University, Montreal, Quebec, Canada Title: "Genetic and Nutritional Deficiencies in Folate Metabolism: Impact on Complex Traits"	Host: Natalia Krupenko Sponsor: Biochemistry
April 21, 2011	Roderick Dashwood, Ph.D. Oregon State University PI & Director, Cancer Chemoprotection Program Linus Pauling Institute Professor, Department of Environmental and Molecular Toxicology Corvallis, OR Title: "Metabolism as a key to HDAC inhibition by dietary chemoprotective agents"	Host: Dr. Michael Wargovich Sponsor: Pharmacology
	APRIL 27, 2011: CLASSES END
April 28, 2011	Seminar Cancelled
May 5, 2011	Seminar Cancelled
May 12, 2011	Seminar Cancelled
May 19, 2011	Adrian Lee, Ph.D. University of Pittsburgh Schools of the Health Sciences Visiting Professor, Department of Pharmacology Chemical Biology Director, Women’s Cancer Research Center Pittsburg, PA Title: “Targeting IGF-IR in breast cancer”	Host: Dr. Carola Neumann Sponsor: Pharmacology
May 26, 2011	Seminar Cancelled
June 2, 2011	Vassiliki Karantza, M.D., Ph.D. UMDNJ-Robert Wood Johnson Medical School The Cancer Institute of New Jersey New Brunswick, NJ Title: TBA	Host: Dr. Carola Neumann Sponsor: Pharmacology
Fall 2010
September 16, 2010	Sumanth D. Prabhu, M.D. Professor and University Scholar Division of Cardiovascular Medicine University of Louisville Health Sciences Center Title: “Inflammatory Pathways in Heart Failure”	Host: Dr. Francis G. Spinale Sponsor: MCBP
September 23, 2010	Yusen Liu, PhD Associate Professor of Pediatrics (with tenure) Center for Perinatal Research The Research Institute at Nationwide Children’s Hospital Department of Pediatrics The Ohio State University College of Medicine Title: “MAP Kinase Phosphatase-1, a Critical Regulator of Innate Immunity and Beyond”	Host: Dr. Keith L. Kirkwood Sponsor: Microbiology/Division of Basic Sciences
September 30, 2010	Alexander Tropsha, Ph.D. Professor and Chair of Medicinal Chemistry and Natural Products UNC Chapel Hill School of Pharmacy Chapel Hill, North Carolina Title: “Chemocentric Informatics: Computational Analysis of Integrated Chemical-Biological Data Sources to Enable Molecular Probe and Drug Discovery”	Host: Dr. Yuri Peterson Sponsor: Lanier NSF Grant
October 7, 2010	Dr. Bryan R. Cullen James B. Duke Professor Department of Molecular Genetics and Microbiology Director Duke University Center for Virology Duke University Medical Center – Durham, North Carolina Title: “Viruses, microRNAs and RNA interference.”	Host: Dr. Mirko Hennig Sponsor: Biochemistry/Division of Basic Sciences
October 14, 2010	Paul D. Roepe, Ph.D. Professor and Chair of Chemistry Professor of Biochemistry and Molecular Biology and Tumor Biology Lombardi Cancer Center Georgetown University Title: "Quinoline Antimalarial Drug Resistance"	Host: Dr. Donald Menick Sponsor: MCBP
October 21, 2010	Ron R. Kopito, Ph.D. Professor Stanford University Department of Biological Sciences Stanford University – Stanford, California Title: "Quality control on the protein assembly line"	Host: Dr. Stephen Lanier Sponsor: MCBP
October 28, 2010	TBA
November 4, 2010	Student Research Day – No Seminar
November 11, 2010	TBA	Host: Craig Crosson Sponsor: MCBP
November 18, 2010	Dr. Fred Marshall Winston John Emory Andrus Professor of Genetics Harvard Medical School Boston, MA Title: "Factors that control transcription and chromatin structure in yeast”	Host: Dr. Deepak Bastia Sponsor: Biochemistry/Division of Basic Sciences
November 25, 2010	Happy Thanksgiving!
December 2, 2010	Leslie B. Gordon, M.D., Ph.D. Staff Scientist Children’s Hospital Boston Department of Anesthesia, Boston, MA Title: “Hutchinson-Gilford Progeria Syndrome: A New Avenue for Cardiovascular and Aging Research Through Rare Disease Discoveries”	Host: Dr. Bryan P. Toole Sponsor: MCBP
December 9, 2010	Dr. Christopher M. Counter Associate Professor Department of Pharmacology and Cancer Biology Duke University Medical Center Title: "Oncogene Addiction: NO Way”	Host: Dr. Besim Ogretman Sponsor: Biochemistry/Division of Basic Sciences
December 16, 2010	Ramon Parsons, M.D., Ph.D. Avon Professor of Pathology & Medicine Leader Breast Cancer Program Institute for Cancer Genetics Herbert Irving Comprehensive Cancer Center Columbia University New York, NY Title: “The PTEN Pathway and Cancer”	Host: Dr. Carola A. Neumann Sponsor: Biochemistry/Division of Basic Sciences
Spring 2010
January 21, 2010	Erica A. Golemis, Ph.D. Senior Member Fox Chase Cancer Center Philadelphia, PA Title: “Nedd9 and Aurora-A: integrating multiple signaling pathways in Cancer”	Host: Dr. Steven Rosenzweig Sponsor: MCBP
January 28, 2010	Harold Ray (Skip) Garner, Jr., Ph.D. Executive Director Virginia Bioinformatics Institute Virginia Tech Title: “Global germline and tumor microsatellite patterns are putative cancer biomarkers, and can be used to identify individual diagnostic loci”	Host: Dr. Jim Zheng Sponsor: Biochemistry
February 4, 2010	John Condeelis, Ph.D. Judith & Burton P. Resnick Chair in Translational Research Professor and Co-Chair, Anatomy & Structural Biology Co-Director, Gruss Lipper Biophotonics Center Scientific Director, Analytical Imaging Facility Director, Tumor Microenvironment and Metastasis Program Albert Einstein Cancer Center Albert Einstein College of Medicine Title: “Microenvironments of metastasis: Insights derived by multiphoton imaging”	Host: Dr. Steven Rosenzweig Sponsor: MCBP
February 11, 2010	Everett C. Pesci, Ph.D. Professor from the Department of Microbiology and Immunology Brody School of Medicine East Carolina University Title: “Quinolone Signaling by Pseudomonas aeruginosa”	Host: Dr. Yong-Mei Zhang Sponsor: Biochemistry
February 18, 2010	Patrick J. Stover, Ph.D. Professor & Director Division of Nutritional Sciences Cornell University Ithaca, NY Title: “Nuclear Folate Metabolism and Folate-associated Cancers and Developmental Anomalies”	Host: Dr. Krupenko Sponsor: Biochemistry
February 25, 2010	Mario Delmar, M.D., Ph.D. Frank Norman Wilson Professor of Cardiovascular Medicine. Professor of Internal Medicine and of Molecular and Integrative Physiology. Director of Basic Science, Division of Cardiovascular Medicine. Co-Director, Center for Arrhythmia Research. University of Michigan Title: "Sodium channels, gap junctions and desmosomes: Tres Amigos at the Intercalated Disc"	Host: Dr. Robert Gourdie Sponsor: MCBP
March 4, 2010	Jim R. Davie, Ph.D. Acting Associate Director -Institute of Cell Biology Professor, Dept. of Biochemistry and Molecular Biology MRC Senior Scientist University of Manitoba Title: “Protein kinase CK2 phosphorylation of HDAC2: Role in complex formation and genome location”	Host: Dr. Donald Menick Sponsor: MCBP
March 6 - 14, 2010	Spring Break
March 18, 2010	No Seminar
March 25, 2010	Michael W. McBurney, Ph.D. Program Director, Cancer Therapeutics, Ottawa Hospital Research Institute Professor of Medicine and Biochemistry, Microbiology and Immunology, University of Ottawa Title: "Physiological Deficits in SirT1-null Mice – the role of sirtuins in aging"	Host: Dr. Donald Menick Sponsor: MCBP
April 1, 2010	No Seminar
April 8, 2010	Tamara Lea Doering, M.D./Ph.D. Washington University School of Medicine Division of Biology and Biomedical Sciences Department of Molecular Microbiology St. Louis, MI Title: “How sweet it is! Capsule synthesis in the pathogenic fungus Cryptococcus neoformans”	Host: Dr. Maurizio Del Poeta Sponsor: Biochemistry & Burroughs Wellcome Fund
April 15, 2010	Bradley K. Yoder, Ph.D. Professor of Cell Biology University of Alabama Birmingham Title: “Emerging Role of Cilia in Development and Disease”	Host: Dr. Courtney Haycraft Sponsor: MCBP
April 22, 2010	Jack D. Keene, Ph.D. James B. Duke Professor Department of Molecular Genetics and Microbiology Duke University Medical Center Title: "Dynamic Post-transcriptional RNA Operons and Regulons"	Host: Dr. Tilman Heise Sponsor: Biochemistry
April 29, 2010	W. Daniel Stamer, Ph.D. Professor and Associate Head of Ophthalmology and Vision Science Professor of Pharmacology & Physiology The University of Arizona Title: “Biomechanical and Pharmacological Regulation of Conventional Outflow”	Host: Dr. Craig Crosson Sponsor: MCBP
May 6, 2010	Paul Dent, Ph.D. Professor of Biochemistry & Molecular Biology Virginia Commonwealth University School of Medicine Title: “Sorafenib and HDAC inhibitors synergistically interact to kill GI tumor cells through ceramide dependent CD95 activation”	Host: Dr. Christina Voelkel-Johnson Sponsor: Microbiology & Immunology
May 13, 2010	Nicholas Tonks, Ph.D. Professor, Cold Spring Harbor Laboratory Cold Spring Harbor, New York Title: “Signal transduction from a protein tyrosine phosphatase perspective”	Host: Dr. Carola A. Neumann Sponsor: Pharmacology
May 20, 2010	Gregg Silverman, M.D. Professor of Medicine Director, Laboratory of B cell Immunobiology UCSD School of Medicine Title: "The dual inhibitory receptor hypothesis: Autoantibodies and immune homeostasis"	Host: Dr. Stephen Tomlinson Host: Dr. Gary Gilkeson Sponsor: Microbiology & Immunology
May 27, 2010	TBA Title: TBA	Host: TBA Sponsor: Pharmacology
June 10, 2010	Thomas L. Clemens Department of Orthopaedic Surgery Johns Hopkins University Editor-in-Chief, Journal of Bone and Mineral Research Title: "Insulin signaling in osteoblasts regulates bone and body composition".	Host: Lauren Ball Sponsor: Microbiology & Immunology
June 17, 2010	Kamal Khanna, Ph.D. Assistant Professor University of Connecticut Health Center Department of Immunology Title: “Visualizing endogenous CD8 T cell immune response to infection: important role of Sphingosine-1-phosphate receptors"	Host: Dr. Shikhar Mehrotra Sponsor: Microbiology & Immunology
Fall 2009
September 24, 2009	James Russell Williamson, Ph.D. Department of Molecular Biology Department of Chemistry The Skaggs Institute for Chemical Biology The Scripps Research Institute Title: Dynamics of Ribosome Assembly using Mass Spectrometry	Host: Dr. Mirko Hennig Sponsor: Biochemistry
October 1, 2009	Steven Ebert, Ph.D. Assoc. Professor and PhD Program Coordinator Burnett School of Biomedical Sciences University of Central Florida Title: Generation of Novel Reporter Stem Cells and their Application for Molecular Imaging of Cardiac-Differentiated Stem Cells In Vivo	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
October 15, 2009	Roger A. Sabbadini, Ph.D. Professor of Biology, Emeritus Founder, Vice President & Chief Scientific Officer Of Lpath, Inc. San Diego State University Title: Therapeutic antibodies targeting Sphingosine-1-phosphate in the treatment of cancer and ocular pathologies.	Host: Dr. Obeid, Hannun & Ogretmen Sponsor: COBRE/Biochemistry
October 22, 2009	Alan M. Jones, Ph.D. George & Alice Welsh Distinguished Professor The University of North Carolina at Chapel Hill Title: Sui Generis Yet Applicable G-protein Cycling in the Model Organism, Arabidopsis	Host: Stephen M. Lanier Sponsor: Provost Office Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
October 29, 2009	Joan Heller Brown, Ph.D. Professor of Pharmacology Cancer Biology Program University of California, San Diego Title: “G-protein coupled receptors in growth and survival: how RhoA signaling makes it happen”	Host: Dr. Donald Menick Sponsor: MCBP/ Cardiovascular Training Grant
November 12, 2009	Larry V. Hryshko, Ph.D. Professor of Physiology Institute of Cardiovascular Sciences University of Manitoba Cardiac Electrophysiology Title: Therapeutic Potential of Sodium-Calcium Exchange Inhibitors	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
November 19, 2009	Donald M. Bers, Ph.D. Distinguished Professor & Chair Sylvia Chair for Cardiovascular Research Department of Pharmacology University of California, Davis Title: Ca Signaling in Cardiac Myocytes	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
December 3, 2009	Dr. Ira J. Goldberg Columbia University College of Physicians & Surgeons Department of Medicine Division of Preventive Medicine and Nutrition New York, NY Title: Correcting Cardiac Lipotoxicity	Host: Dr. Ashley Cowart Sponsor: Biochemistry
December 10, 2009	Walter J. Koch, Ph.D., FAHA W.W. Smith Professor of Medicine Director, Center for Translation Medicine Jefferson Medical College, Philadelphia, PA Title: GRK’s in the Failing Heart: Are We Barking up the Right Tree?	Host: Dr. Donald Menick Sponsor: MCBP/Cardiovascular Training Grant
December 17, 2009	Gideon Dreyfuss, Ph.D. Isaac Norris Professor Investigator, Howard Hughes Medical Institute University of Pennsylvania School of Medicine Title: RNPs: Regulators of RNA Metabolism and Therapeutic Targets in Neurodegenerative Disease	Host: Dr. Tilman Heise Sponsor: Biochemistry
Spring 2009
January 15, 2009	Paul D. Drew, Ph.D. Professor Neurobiology and Developmental Sciences Director Cellular and Molecular Neuroscience Center University of Arkansas for Medical Sciences Title: "Peroxisome Profilferator-Activated Receptors: Potential Modulators of Multiple Sclerosis"	Host: Dr. Inderjit Singh Sponsor: MCBP Program
January 22, 2009	Nahum Sonenberg, Ph.D. Host: Dr. Tilman Heise Professor Biochemistry and McGill Cancer Centre Sponsor: Biochemistry Rosalind and Morris Goodman Cancer Centre McGill University Title: "Translation control in cancer and miRNA function"
January 29, 2009	Michael Rosol, Ph.D. Assistant Professor of Radiology Medical University of South Carolina Title: "Dynamic tracking of human hematopoietic stem cells in mice"	Sponsor: MCBP
February 5, 2009	Bruce D. Carter, Ph.D. Professor of Biochemistry Vanderbilt University Medical Center Title: "Mechanisms of neuronal apoptosis and phagocytic clearance in the developing of peripheral nervous system"	Host: Dr. Hiroko Hama Sponsor: Biochemistry
February 12, 2009	Kenneth D. Philipson, Ph.D. Distinguished Professor of Physiology & Medicine David Geffen School of Medicine University of California, Los Angeles Title: "Cardiac Sodium-Calcium Exchange: A Tale of Two Sites"	Host: Dr. Donald R. Menick Sponsors: MCBP & Cardiovascular Training Grant
February 19, 2009	Roel van der Veen, Ph.D. Associate Professor of Neurology University of Southern California, Keck School of Medicine Title: "Innate myeloid cells regulate T cell activity through interacting nitric oxide and Superoxide"	Host: Dr. Inderjit Singh Sponsor: MCBP Program
February 26, 2009	Alexadra Lucas, M.D. Section Head Vascular Research University of Florida Title: "The Serpin Saga – Treatment of Inflammation in Vascular Disease"	Host: Dr. Francis Spinale Sponsor: MCBP & Cardiovascular Training Grant
March 5, 2009	Kathleen L. Gould, Ph.D. Professor of Cell & Developmental Biology HHMI Investigator University of Southern California Title: "Split decisions: regulating the end of the cell cycle"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
March 7-15, 2009	Spring Break
March 19, 2009	TBA
March 26, 2009	David Giedroc, Ph.D. Professor Department of Chemistry Indiana University Title: "RNA structural and functional determinants of the 5’ and 3’ tips of the coronavirus genome"	Host: Dr. Mirko Henning Sponsor: Biochemistry
April 2, 2009	TBA
April 9, 2009	William A. Dunn, Jr., Ph.D. Professor Department Anatomy and Cell Biology University of Florida College of Medicine Gainesville, Florida Title: "Endogenous and Exogenous Regulation of Pexophagy and Autophagy"	Host: Dr. John Lemasters Sponsor: College of Pharmacy
April 16, 2009	W. Gray Jerome, Ph.D., FAHA Pathology Vanderbilt University Medical Center U2206 MCN 1161 21st Ave., South Nashville, TN 37232-2561 615-322-5530 jay.jerome@vanderbilt.edu Title: "The Role of Lysosomes in Atherosclerosis"	Host: Dr. Samar Hammad Sponsor: MCBP
April 23, 2009	Stuart A. Aaronson, M.D. Professor and Chairman Department of Oncological Sciences Mount Sinai School of Medicine Title: "Translating Cancer Gene Discovery to the Clinic"	Host: Dr. Dennis Watson Sponsor: MCBP
April 30, 2009	TBA
May 7, 2009	Warren D. Kruger, Ph.D. Senior Member Popular Science Division Fox Chase Cancer Center Title: "How to Fix a Broken Protein"	Host: Dr. Sergey Krupenko
Fall 2008
September 4, 2008	Robert C. Dickson, PhD Professor of Molecular and in Cellular Biochemistry Lipidomics & Pathobiology University of Kentucky Title: Do Sphingolipids Play Roles in Regulating Lifespan in Yeast?	Host: Dr. Ashley Cowart Sponsor: COBRE
September 11, 2008	Robert M. Gemmill, PhD Melvyn Berlinsky Chair in Cancer Research Prof. of Medicine, Hematology/Oncology Division Medical University of South Carolina Title: Linkage of Lipid Homeostasis with Protein Translation through the TRC8/RNF139 Kidney Cancer Tumor Suppressor
September 18, 2008	Ward B. Watt, PhD Professor of Biology Trustee and President, California Academy of Sciences Department of Biological Sciences Stanford University Sanford, California Title: Evolution of Protein Structure and Function: From Molecules to Ecosystems	Host: Dr. Christopher Davies Sponsor: MCBP Program
October 2, 2008	Wendy Bollag, Ph.D., Professor Institute of Molecular Medicine and Genetics Medical College of Georgia Augusta, Georgia Title: Priming of Aldosterone Secretion: Phospholipase D and A Type of Cellular Memory	Host: Dr. Tom Morinelli Sponsor: MCBP Program
October 9, 2008	Jakob Vinten-Johansen, MS, PhD, Professor Division of Cardiothoracic Surgery Department of Surgery Associate Professor of Physiology Emory University School of Medicine Director, Cardiothoracic Research Laboratory Carlyle Fraser Heart Center Emory Crawford Long Hospital Title: Cardiac Self-Defense 101: Innate Cardioprotection from Ischemia- Reperfusion Injury with Postconditioning	Host: Dr. Frank G. Spinale Sponsor: MCBP Program
October 16, 2008	Wonhwa Cho, PhD Distinguished Professor of Chemical Biology Department of Chemistry University of Illinois at Chicago Title: Spatiotemporal Regulation of Cellular Processes by Lipids and Lipid-binding Proteins: Proteomics and Single Molecule Studies	Host: Dr. Yusuf Hannun Sponsor: Biochemistry
October 23, 2008	Michel Bouvier PhD, FCAHS Host: Dr. Stephen Lanier Professeur Departement de Biochimie Sponsor: MCBP Program Institut de Recherche en Immunologie et Cancer Directeur Groupe de Recherche Universitaire sur le Médicament Toronto, Canada Title: Molecular Basis of G Protein-coupled Receptors Functional Selectivity; Linking Ligand-based Signaling to Specific Protein Complex Assemblies
October 30, 2008	Thomas Michel, MD, PhD Dean for Education, Harvard Medical School Professor of Medicine and Biochemistry Federman Chair in Medical Education Harvard University Senior Physician in Cardiovascular Medicine Brigham and Women’s Hospital Title: Nitric Oxide Synthases and Cardiovascular Signal Transduction	Host: Dr. Yusuf Hannun Sponsor: Biochemistry
November 6, 2008	NO SEMINAR Student Research Day (November 7, 2008)
November 13, 2008	Jonathan D. Dinman, PhD, Professor Department of Cell Biology & Molecular Genetics University of Maryland College Park, Maryland Title: Programmed Ribosomal Frameshifting: It’s Not Just for Viruses Anymore	Host: Dr. Mirko Hennig Sponsor: Biochemistry
November 20, 2008	Yuan Liu, PhD, Assistant Professor Department of Biology Georgia State University Atlanta, Georgia Title: Modulating Leukocyte Inflammatory Responses by Cell Surface Receptors	Host: Dr. Titus Reaves Sponsor: MCBP Program
December 4, 2008	TBA
December 11, 2008	Jerard Hurwitz, Ph.D. Sloan-Kettering Institute Professor Cornell University Medical College Head, William Randolph Hearst Laboratory Of Radiation Biology Memorial Sloan-Kettering Cancer Center New York, New York Title: TBA	Host: Dr. Deepak Bastia Sponsor: Biochemistry
Spring 2008
January 10, 2008	Sam W. Lee, Ph.D. Associate Professor Harvard Medical School Associate Director, Cutaneous Biology Research Center Massachusetts General Hospital Boston, Massachusetts Title: Cell Fate Decision by Tumor Suppressor p53: Live or Die	Host: Dr. S. Krupenko Sponsor: Biochemistry
January 17, 2008	G. David Roodman, MD, PhD Professor of Medicine and Division of Hematology and Oncology Pediatrics University of Pittsburgh Title: Novel Targets for Treating Myeloma Bone Disease	Host: Dr. Sakamuri V. Reddy Sponsor: MCBP Program
January 24, 2008	Susan R. George, MD, FRCP, FACP Professor of Medicine and Pharmacology University of Toronto Canada Research Chair in Molecular Neuroscience Head, Molecular Pharmacology Centre for Addiction and Mental Health Endocrinologist, University Health Network Title: Homo- and Hetero-oligomerization of G Protein Coupled Receptors: Novel Insights into Receptor Trafficking and Function	Host: Dr. Steve Lanier Sponsor: MCBP Program
January 31, 2008	Robert A. Sclafani, Ph.D. Professor and Interim Chairman Biochemistry and Molecular Genetics University of Colorado Health Sciences Center Title: Regulation of Genomic Replication and Fidelity by Cdc7-Dbf4 Kinase	Host: Dr. Deepak Bastia Sponsor: Biochemistry
February 7, 2008 ogy Transfer	Ryan N. Fiorini, M.B.A., Ph.D. Licensing and Technology Analyst MUSC Foundation for Research Development Title: The Basics of Intellectual Property and Technol
February 14, 2008	Douglas C. Eaton, Ph.D. Distinguished Professor and Chairman Department of Physiology Director, Center for Cell & Molecular Signaling Emory University Medical School Atlanta, Georgia Title: Direct Activation of the IGF-1 Receptor by Aldosterone	Host: Dr. Darwin Bell Sponsor: MCBP/ and Division of Nephrology
February 21, 2008	No Seminar
February 28, 2008	Maria Joan Curcio, Ph.D. Professor and Research Scientist Wadsworth Center Developmental Genetics and Bioinformatics New York State Department of Health Title: Yeast Retrogenomics: The Role of Retrotransposons and Retrosequences in Genome Restructuring	Host: Dr. Deepak Bastia Sponsor: Biochemistry
March 6, 2008	Dean’s office uses Room 125
March 13, 2008	SPRING BREAK
March 20, 2008	Cheryl A. Kitt, Ph.D. Deputy Director of the Center for Scientific Review National Institutes of Health Title: Enhancing Peer Review: NIH/CSR Challenges	Host: Dr. Stephen M. Lanier Sponsor: MCBP Program
March 27, 2008	No Seminar
April 3, 2008	Raghu Kalluri, Ph.D. Associate Professor of Medicine Harvard Medical School and Beth Israel Deaconess Medical Center Chief, Division of Matrix Biology Boston, Massachusetts Title: Tumor Microenvironment in Cancer Progression and Metastasis	Host: Student, Tejas Tirodkar Sponsor: Dean’s Seminar Series Speaker College of Graduate Studies
April 10, 2008	John D. York, Ph.D. Investigator, Howard Hughes Medical Institute Department of Pharmacology and Cancer Biology Duke University Medical Center Durham, North Carolina Title: An Inositol Phosphate Code Essential for Development and Cellular Adaptation	Host: Dr. Besim Ogretmen Sponsor: Biochemistry
April 17, 2008	Jay A. Tischfield, Ph.D. Duncan and Nancy MacMillan Professor of Genetics and Chair Department of Genetics Nelson Biological Labs Rutgers University Piscataway, New Jersey Title: DNA Repair and Recombination on Somatic versus Embryonic Stem Cells	Host: Dr. Donald R. Menick Sponsor: MCBP Program
April 24, 2008	Suneel S. Apte, M.B.B.S., D. Phil. Staff Department of Biomedical Engineering The Cleveland Clinic Foundation Cleveland, Ohio Title: Cooperative Developmental Roles of ADAMTS Proteases	Host: Dr. Christine Kern Sponsor: MCBP Program
May 1, 2008	Jeffery Twiss, M.D., Ph.D. Head, Neuroscience Research Laboratory Department of Biomedical Research Nemours Biomedical Research Alfred I. duPont Hospital for Children Wilmington, Delaware Title: Regulating Neuronal mRNA Transport – A New Route for Neural Repair	Host: Dr. Donald R. Menick
Fall 2007
September 13, 2007	Walter Holleran, PharmD Associate Adjunct Professor Dermatology and Pharmaceutical Chemistry Member, UCSF Comprehensive Cancer Center University of California at San Francisco San Francisco, California Title: "Skin Sphingolipids: Metabolism, Transport & Functions"	Host: Dr. Hiroko Hama Sponsor: Biochemistry
September 20, 2007	Rosemarie M. Booze, Ph.D. Professor and Bicentennial Endowed Chair of Behavioral Neuroscience University of South Carolina Columbia, South Carolina Title: "HIV and Drugs of Abuse: Neurodegenerative Mechanisms"	Host: Dr. Inderjit Singh Sponsor: MCBP Program
September 27, 2007	Michael J. Wargovich, Ph.D. Professor of Cell and Molecular Pharmacology Director, Cancer Chemoprevention Program Medical University of South Carolina Title: "Prevention of Colon Cancer: Inflammation and Traditional Medicine"
October 4, 2007	Vytas A. Bankaitis, PhD Professor and Chair Dr. Yusuf Hannun Department of Cell & Developmental Biology University of North Carolina School of Medicine Chapel Hill, North Carolina Title: "A High Resolution View of the Collaboration Between Phosphatidylinositol Transfer Proteins and Lipid Kinases: New Paradigms for the Regulation of Phosphoinositide Signaling"	Host: Dr. Besim Ogretmen Sponsor: Biochemistry
October 11, 2007	Robert Skoff, PhD Professor of Anatomy Wayne State University Detroit, Michigan Title: "Sex Hormones: What they do to your Oligodendrocytes"	Host: Dr. Inderjit Singh Sponsor: MCBP Program
October 18, 2007	Sheldon E. Litwin, M.D. Professor Internal Medicine/Cardiology Director, Cardiology Fellowship Cardiovascular Training Grant Director of Cardiovascular Imaging University of Utah Hospital Salt Lake City, Utah Title: "Obesity and the Heart: New Perspectives on a New Epidemic"	Host: Dr. Donald Menick Sponsor: MCBP and NIH
October 25, 2007	Steve J. Brill, PhD Professor Department of Molecular Biology and Biochemistry Rutgers University Piscataway, New Jersey Title: "Genetic Control of Genome Stability in Yeast: A Novel Ubiquitin Ligase Implicates a Role for Sumoylation"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
November 1, 2007	NO SEMINAR - Student Research Day (November 2, 2007)
November 8, 2007	Donald M. Bers, PhD James R. DePauw Professor of Physiology Chair, Department of Physiology and NIH Cardiovascular Training Loyola University Chicago Grant Stritch School of Medicine Maywood, Illinois Title: "Ca and CaMKII in Heart Failure: Systolic Dysfunction, Arrhythmogenesis & Transcriptional Regulation"	Host: Dr. Don Menick Sponsor: MCBP Program
November 15, 2007	CANCELLED Gökhan Hotamisligil, MD, PhD James Stevens Simmons Professor of Genetics and Metabolism Biochemistry Department of Genetics and Complex Diseases Harvard School of Public Health Boston, Massachusetts	Host: Dr. Can E. Senkal Sponsor: Dean’s Seminar Series/
November 22, 2007	Thanksgiving Break
November 29, 2007	Robert S. Kass, PhD Chairman, Department of Pharmacology David Hosack Professor of Pharmacology Cardiovascular Training Grant Columbia University New York, New York Title: "General Lessons from Rare Congenital Arrhythmias"	Host: Dr. Steve Kubalak Sponsor: MCBP and NIH
December 6, 2007	NO SEMINAR (Room 125 not available)
December 13, 2007	Susan Forsburg, Ph.D. Professor Biological Sciences University of Southern California Los Angeles, California Title: "Replication, Repair, and Chromatin in s. pombe"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
Spring 2007
January 11, 2007	Mirko Hennig, Ph.D. Assistant Professor Department of Biochemistry and Molecular Biology Medical University of South Carolina Title: "HIV-1 Latency – The Role of the Regulatory Protein Rev"
January 18, 2007	Elizabeth Murphy, Ph.D. Head, Cardiac Physiology Section Vascular Medicine Branch NHLBI, NIH Bethesda, Maryland Title: "Cardioprotection: The Role of Mitochondria, Calcium and GSK-3beta"	Host: Dr. Donald R. Menick Sponsor: MCBP Program
January 25, 2007	No Seminar
February 1, 2007	P. Darwin Bell, Ph.D. DCI Professor of Medicine Medical University of South Carolina Title: "Macula Densa-Juxtaglomerular Signaling"
February 8, 2007	Curtis C. Harris, M.D. Chief, Laboratory of Human Carcinogenesis Chief of Molecular Genetics & Carcinogenesis Section NIH, NCI, CCR Clinical Professor of Medicine and Oncology Georgetown University School of Medicine Title: "Inflammation and Cancer"	Host: Student Peko Tsuji Dean’s Seminar Series Speaker
February 15, 2007	Daniel M. Raben, Ph.D. Associate Professor The Johns Hopkins University CANCELLED BUT RESCHEDULED FOR APRIL 5, 2007	Host: Dr. Lina Obeid Sponsor: Biochemistry/MCBP
February 22, 2007	Kyu-Ho Lee, M.D., Ph.D. Assistant Professor of Pediatrics Division of Pediatric Cardiology Cardiovascular Developmental Biology Center Medical University of South Carolina Title: "Compartmental Nkx2.5 Regulation Yields Insights Into Cardiac Induction, Lineage and Fate Decisions"
March 1, 2007	Michael V. Johnston, M.D. Chief Medical Director Kennedy Krieger Institute Professor of Neurology, Pediatrics, and Physical Medicine and Rehabilitation Johns Hopkins School of Medicine Baltimore, Maryland Title: "Clinical Disorders of Brain Plasticity"	Host: Dr. Bernard Maria Charles P. Darby Children’s Research Institute
March 8, 2007	Jonathan Lytton, Ph.D. Professor of Biochemistry and University of Calgary Canada Title: "The NCKXs: A Unique Branch of the Sodium-Calcium Exchanger Family"	Host: Dr. Donald Menick Sponsor: Cardiovascular Molecular Biology Training Grant and MCBP Program
March 15, 2007	SPRING BREAK – March 10-18, 2007
March 22, 2007	Jeffrey L. Benovic, Ph.D. Professor and Chair Department of Biochemistry and Molecular Biology Thomas Jefferson University Philadelphia, Pennsylvania Title: "Arresting Developments in Receptor Signaling and Trafficking"	Host: Drs. Perry Halushka and Lou Luttrell Sponsor: MCBP Program
March 29, 2007	W. Scott Moye-Rowley, Ph.D. Professor and Executive Associate Head Department of Molecular Physiology & Biophysics Carver College of Medicine University of Iowa Iowa City, Iowa Title: "Coordinate Control of Sphingolipid Biosynthesis and Multidrug Resistance"	Host: Dr. Ashley Cowart Sponsor: Biochemistry
April 5, 2007	Daniel M. Raben, Ph.D. Associate Professor Departments of Biological Chemistry, Oncology and Physiology The Johns Hopkins University Baltimore, Maryland Title: "Dual Regulation of Diacylglycerol Kinase-theta: An Interfacial Signaling Enzyme"	Host: Dr. Lina Obeid Sponsor: Biochemistry/MCBP
April 12, 2007	Rachel Wong, Ph.D. Professor Department of Biological Structure University of Washington Seattle, Washington Title: "Imaging Circuit Assembly in the Vertebrate Retina"	Host: Dr. Rosalie Crouch Sponsor: MCBP Program
April 19, 2007	Rosalie C. Sears, Ph.D. Professor, Department of Genetics Cancer Institute Oregon Health & Science University Portland, Oregon Title: "A Role for c-Myc Protein Stabilization in Cancer"	Host: Dr. Besim Ogretmen Sponsor: Biochemistry
April 26, 2007	Alan C. Rapraeger, Ph.D. Professor and Vice-Chair for Education Department of Pathology and Laboratory Medicine University of Wisconsin 1300 University Avenue Madison, WI 53706 Title: "Regulation of Integrin Activity by Syndecan-1 during Tumorigenesis and Angiogenesis"	Host: Dr. Tien Hsu Sponsor: MCBP Program
Fall 2006
September 21, 2006	Melvin L. DePamphilis, Ph.D., Section Chief Member, Senior Biomedical Research Service National Institute of Child Health and Human Development National Institutes of Health Bethesda , Maryland Title: "ORC Cycle: A Novel Mechanism for Regulating Genome Duplication in Mammalian Cells"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
September 28, 2006	John J. Lemasters, M.D., Ph.D. South Carolina COEE Endowed Chair in Advanced Cellular Technologies Pharmaceutical Sciences and Biochemistry and Molecular Biology Medical University of South Carolina Title: "Mitochondrial Membrane Permeabilization in Pathogenesis"
October 5, 2006	S. Michael Jazwinski (CANCELLED)
October 12, 2006	Muthu Periasamy, Ph.D. Professor and Chair Department of Physiology and Cell Biology Ohio State University College of Medicine Columbus , Ohio Title: "SERCA Pump Rescues Cardiac Function in Ischemic Heart Disease"	Host: Dr. Dhan Kuppuswamy Sponsor: MCBP Program and NIH Cardiovascular Training Grant
October 19, 2006	Craig D. Logsdon, Ph.D. Lockton Distinguished Prof. for Pancreatic Cancer Resch Departments of Cancer Biology and Medical Oncology UT MD Anderson Cancer Center , Unit 953 Houston , TX 77030 Title: "Exploiting Pancreatic Cancer Specific Genes as Therapeutic Targets"	Host: Dr. Michael Mitas Sponsor: MCBP Program
October 26, 2006	TBA
November 2, 2006	NO SEMINAR RESEARCH DAY - November 3, 2006
November 9, 2006	Jeffrey Rosen, Ph.D. C.C. Bell Professor of Molecular and Cellular Biology and Medicine Distinguished Service Professor Baylor College of Medicine Houston , Texas Title: "Stem/progenitor Cells in the Etiology and Treatment of Breast Cancer"	Host: Dr. Dennis Watson Sponsor: MCBP Program
November 16, 2006	Brian Popko, Ph.D. Jack Miller Professor in Neurological Diseases Director, Jack Miller Center for Peripheral Neuropathy Associate Chair for Research, Department of Neurology University of Chicago Chicago , Illinois Title: "ER Stress Modulates the Response of Oligodendrocytes to CNS Inflammation"	Host: Dr. Hiroko Hama Sponsor: Biochemistry
November 23, 2006	THANKSGIVING
November 30, 2006	Joseph Y. Cheung, M.D., Ph.D. Capizzi Professor of Medicine Chief of Nephrology Thomas Jefferson University Philadelphia , PA 19107 Title: "Regulation of Cardiac Na/Ca Exchanger by Phospholemman"	Host: Dr. Donald Menick Sponsor: MCBP Program
December 7, 2006	Ann Ramsdell, Ph.D. Health Science Foundation Assistant Professor Developing Scholar Lecture Department of Cell Biology and Anatomy Medical University of South Carolina Title: "Left-Right Asymmetry and Congenital Cardiac Defects: The Heart of the Matter in Left-Right Axis Determination"
Spring 2006
January 12, 2006	Joel A. Huberman, Ph.D Professor Cellular and Molecular Biology State University of New York at Buffalo Buffalo, New York Title: "What is the Difference Between Early-firing and Late-Firing DNA Replication Origins?"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
January 19, 2006	Ziad H. Nahas, M.D. Associate Professor Department of Psychiatry and Behavioral Sciences Medical University of South Carolina Health Sciences Foundation Developing Scholar Award Title: "Neuromodulation Treatments for Depression"
January 26, 2006	Paul B. Fisher, Ph.D. Professor of Clinical Pathology Director, Neuro-Oncology Research Michael and Stella Chernow Urological Cancer Research Scientist Columbia University Medical Center College of Physicians and Surgeons New York, NY Title: "Terminal Differentiation and Cellular Senescence: Opposite Sides of the Same Coin"	Host: Dr. Dennis Watson Sponsor: MCBP
February 2, 2006	Maurizio Del Poeta, M.D. Associate Professor of Biochemistry & Molecular Biology Medical University of South Carolina Health Sciences Foundation Developing Scholar Award Title: "Sphingolipids in Fungal Pathogenesis: The Role of Glucosylceramide"
February 9, 2006	Dr. Fitzgerald (CANCELLED)	Host: Dr. Yusuf Hannun Sponsor: Biochemistry
February 16, 2006	Gary W. Litman, Ph.D. Professor of Biochemistry & Molecular Biology University of South Florida College of Medicine St. Petersburg, FL Title: "Reconstructing Immune Phylogeny"	Host: Dr. Greg Warr Sponsor: MCBP
February 23, 2006	Arnold J. Levine, Ph.D. Harry C. Wiess Professor in the Life Sciences, Emeritus Professor of Molecular Biology, Emeritus Professor, Institute for Advanced Study, School of Natural Sciences< Princeton University Professor, Pediatrics and Biochemistry Cancer Institute of New Jersey/UMDNJ New Brunswick, NJ Title: "A Single Nucleotide Polymorphism in the Human MDM-2 Gene that Modifies the p53 Response and Results in an Early Age of Onset of Cancers"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
March 2, 2006	Gary Landreth, Ph.D. Professor Department of Neurosciences and Neurology Alzheimer Research Laboratory Case Western Reserve University School of Medicine Cleveland, Ohio Title: "Inflammatory Mechanisms in Alzheimer's Disease"	Host: Don Menick Sponsor: MCBP
March 9, 2006	George K. Michalopoulos, M.D., Ph.D. Professor and Chairman Department of Pathology University of Pittsburgh School of Medicine Pittsburgh Pennsylvania Title: TBA	Host: Dr. Yusuf Hannun Sponsor: Biochemistry
March 16, 2006	No Seminar - Spring Break
March 23, 2006	Dianna M. Milewicz, MD, PhD Professor and Director Division of Medical Genetics Department of Internal Medicine President George H. W. Bush Chair of Cardiac Medicine, Texas Heart Institute University of Texas Medical School Title: "Genetic Basis of Aortic Aneurysm and Dissection"	Host: Dr. Perry Halushka Sponsor: MCBP
March 30, 2006	Phillip A. Sharp, Ph.D. Institute Professor Center for Cancer Research Massachusetts Institute of Technology Title: "The Surprising Biology of Small RNA"	Host: Mara Lennard, Grad Stud Sponsor: Biochemistry
April 6, 2006	TBA
April 13, 2006	David J. Newman, Ph.D. Natural Products Branch Developmental Therapeutics Program National Cancer Institute Frederick, Maryland	Host: Dr. Peter Moeller & Tracey Schock Sponsor: MCBP
April 20, 2006	H. Alex Brown, Ph.D. Ingram Associate Professor of Cancer Research Vanderbilt University Title: TBA	Host: Dr. Lina Obeid Sponsor: Biochemistry
April 27, 2006	Henk E.D.J. ter Keurs Professor Department of Physiology and Biophysics University of Calgary Calgary, Alberta, Canada Title: "Non Uniform Contraction of Myocardium is Arrhythmogenic: A Role of Calcium Dissociation from the Myofilaments"	Host: Dr. George Cooper Sponsor: MCBP
Fall 2005
Sept. 29, 2005	Silvia Finnemann, Ph.D. Associate Professor of Cell Biolog in Ophthalmology Dyson Vision Research Institute Weill Medical College of Cornell University New York, New York Title: "Timing is Everything: Control of Daily Retinal Phagocytosis and Adhesion by Integrin Receptor Signaling"	Host: Dr. Rosalie Crouch Sponsor: MCBP Program
October 6, 2005	Thomas H. Fischer, Ph.D. Research Associate Professor Department of Pathology and Laboratory Medicine University North Carolina Chapel Hill, North Carolina Title: "Bioengineering of Rehydrated, Lyophilized Platelets for Vascular Wound Site Imaging and Stabilization"	Host: Dr. Robin Muise-Helmericks Sponsor: MCBP Program
October 13, 2005	Masayori Inouye, Ph.D. Professor and Chairman Department of Biochemistry University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School Piscataway New Jersey Title: "mRNA Interferase, a Novel Mechanism for Cell Growth Regulation"	Host: Dr. Hiroko Hama Sponsor: Biochemistry
October 20, 2005	Kenneth D. Poss, Ph.D. Assistant Professor Cardiovascular Training Grant Duke University Durham, North Carolina Title: "Molecular Insights into Heart Regeneration in Zebrafish"	Host: Dr. Steve Kubalak Sponsor: MCBP Program and Department of Cell Biology
October 27, 2005	Donald M. Bers, Ph.D. Professor and Chair of Physiology Loyola University Stritch School of Medicine Mayfield, Illinois Title: "Ca and CaMKII in Cardiac EC-Coupling and Nuclear Signaling in Heart Failure"	Host: Dr. Donald Menick Sponsor: MCBP Program and Cardiovascular Training Grant
November 3, 2005	(No seminar — Research Day November 4, 2005)
November 10, 2005	Xiaojiang Chen, Ph.D. Professor of Biological Chemistry University of Southern California Los Angeles, California Title: "Two Headed Helicases: Unwinding Double Helix DNA"	Host: Dr. Deepak Bastia Sponsor: Biochemistry
November 17, 2005	Jeffrey E. Green, M.D. Senior Investigator and Head Transgenic Oncogenesis Group Laboratory of Cell Regulation and Carcinogenesis National Cancer Institute Bethesda, Maryland Title: "Conservation of Dysregulated Genetic Networks in Mouse and Human Mammary Cancer: Sifting Through the Haystack Using Systems Biology"	Host: Dr. Dennis Watson Sponsor: MCBP Program
November 24, 2005	November 24, 2005 (No seminar — Thanksgiving)
December 1, 2005	D. Woodrow Benson, M.D., Ph.D. Professor of Pediatrics Director, Cardiovascular Genetics Cincinnati Children's Hospital Medical Center Cincinnati, Ohio Title: "Genetic and Developmental Origins of Pediatric Heart Valve Disease"	Host: Dr. Terry O'Brien Sponsor: MCBP Program and Cardiovascular Training Grant
December 8, 2005	Michael A. Frohman, M.D., Ph.D. Professor of Pharmacology Director, Medical Scientist Training Programz SUNY at Stony Brook, New York Title: "Mito-PLD, a Novel Lipid-Modifying Enzyme That Regulates Mitochondrial Fusion"	Host: Dr. Yusuf Hannun Sponsor: Biochemistry
Spring 2005
January 27, 2005	Stanley H. Appel, M.D. Professor, Department of Neurology Baylor College of Medicine Houston, TX Title: "Inflammation: The Good, the Bad, and The Ugly: Lessons from ALS"	Host: Dr. William R. Tyor Sponsor: MCBP
February 3, 2005	Ronald H. Kaback, M.D. HHMI Investigator and Professor UCLA Los Angeles, CA Title: The Passion of the Permease: from Membrane to Molecule to a Mechanism of Active Transport"	Host: Dr. Donald Menick Sponsor: MCBP
February 10, 2005	John A. McDonald, M.D., Ph.D. Dean, School of Medicine and Vice President for Health Sciences, Reno School of Medicine University of Nevada Reno, Nevada Title" "A Link Between Integrins, Calreticulin and Systolic Dysfunction Revealed by Conditional Transgene Expression in the Adult Mouse Heart"	Host: Dr. George Cooper Sponsor: MCBP
March 3, 2005	Kenneth R. Chien, M.D., Ph.D. Director, Institute of Molecular Medicine UCSD School of MedicineSan Diego, California Title: "Islet-1 Cardiac Progenitors in Development and Disease"	Host: Dr. Steve Kubalak & Sponsor: MCBP
March 10, 2005	Kenneth D. Tew, Ph.D., DSci Professor and Chair, Department of Cell and Molecular Pharmacology and Experimental Therapeutics Medical University of South Carolina Title: "Islet-1 Cardiac Progenitors in Development and Disease"
March 24, 2005	Besim Ogretmen, Ph.D. Assistant Professor of Biochemistry and Molecular Biology Medical University of South Carolina Title: "The Role Ceramide in the Regulation of Cancer Growth and Therapy"
March 31, 2005	Fuad Ziyadeh, M.D. Professor of Medicine University of Pennsylvania School of Medicine Philadelphia, Pennsylvania Title: "Pathogenesis of Diabetic Nephropathy: Role of TGF-beta and VEGF"	Host: Dr. Ayad Jaffa Sponsor: MCBP
April 7, 2005	Rodney Rothstein, Ph.D. Professor Genetics and Development Columbia University College of Physicians and Surgeons New York, New York Title: "Choreography of the DNA Damage Response in Budding Yeast"	Host: Dr. Deepak Bastia Sponsor: Biochemsitry
April 14, 2005	Thomas A. Steitz, Ph.D. Sterling Professor and HHMI Investigator Yale University Branford, Connecticut Title: "Motion in Macromolecular Machines"	Host: Dr. Jeff Hansen Sponsor: Biochemistry
April 21, 2005	David J. Ecker, Ph.D.President Division of Isis Therapeutics Isis Pharmaceutics Carlsbad, California Title: "Technology for Universal Infectious Disease Identification"	Host: Dr. Donald Menick Sponsor: MCBP
April 28, 2005	David J. Kusner, M.D., Ph.D. Associate Professor Departments of Internal Medicine, Immunology, Molecular Biology, & Physiology/Biophysics University of Iowa Inflammation Program Coralville, Iowa Title: "The role of sphingosine kinase in macrophage function and disease pathogenesis"	Host: Dr. Lina Obeid Sponsor: MCBP
May 5, 2005	Jerry W. Shay, Ph.D. Professor of Cell Biology Southland Financial Distinguished Chair in Geriatric Research Associate Director, Cancer Center University of Texas Southwest Dallas, Texas Title: "Aging and Cancer: Are Telomeres and Telomerase the Connection?"	Host: Dr. Besim Ogretmen Sponsor: Biochemistry
Fall 2004
Sept. 16, 2004	Robert K. Yu, Ph.D, MedScD Director and Professor Institute of Molecular Medicine and Genetics Medical College of Georgia School of Medicine Augusta GA Title: "Developmental Regularion of Ganglioside Metabolism in the Nervous System"	Host: Dr. Yusuf Hannun Sponsor: Biochemistry
Sept. 23, 2004	Joseph Heitman, MD, PhD Associate Investigator HHMI Professor Duke University Medical Center Durham, North Carolina Title: "Evolution of the Model Human Fungal Pathogen Cryptococcus Neoformans"	Host: Dr. Maurizio Del Poeta Sponsor: Biochemistry
Sept. 30, 2004	Bryan P. Toole, PhD Professor of Cell Biology and Anatomy Medical University of South Carolina Title: "Hyaluronan and Emmprin: Pericellular Regulators of ErbB2 Signaling, Multidrug Resistance and Malignant Cell Behavior"
Oct. 7, 2004	Morris F. White, Ph.D. Associate Professor of Pediatrics Department of Chemistry and Molecular Pharmacology Howard Hughes Medical Institute Harvard Medical School Boston, Massachusetts Title: "The Role of Irs2 Signaling in Obesity and Diabetes"	Host: Dr. Maria Buse Sponsor: MCBP Program
Oct. 14, 2004	J. Marie Hardwick, PhD Professor Department of Molecular Microbiology and Immunology Johns Hopkins Bloomberg School of Public Health Title: TBA	Host: Yi-Te Hsu Sponsor: Biochemistry
Oct. 21, 2004	John W. Baynes, PhD Carolina Distinguished Professor Department of Chemistry and Biochemistry University of South Carolina Columbia, South Carolina Title: "Chemical Modification of Proteins in Aging, Diabetes and Cardiovascular Disease: The Relationship Between Metabolism and Chemistry in Disease"	Host: Dr. Hiroko Hama Sponsor: Biochemistry
Oct. 28, 2004	Richard P. Visconti, PhD Assistant Professor of Cell Biology and Anatomy Medical University of South Carolina Title: "Adult Bone Marrow Stem Cells in Cardiac Homeostatis and Pathology"
Nov. 4, 2004	Rowena G. Matthews, PhD G. Robert Grennberg Professor and Senior Research Scientist, Life Sciences Institute University of Michigan Ann Arbor, Michigan Title: "Regulation of One-carbon Metabolism in Mammals"	Host: Dr. Sergey Krupenko Sponsor: Biochemistry
Nov. 11, 2004	Robert A. Nicholas, PhD Professor, Department of Pharmacology University of North Carolina Chapel Hill, North Carolina Title: "Antibiotic Resistance in Neisseria gonorrhoeae: Cumulative Effect of Multiple Resistance Genes"	Host: Dr. Chris Davies Sponsor: Biochemistry
Nov. 18, 2004	Emily Wilson, PhD Assistant Professor Department of Medical Physiology Texas A&M Health Science Center College Station, Texas Title: "Modulation of Integrin Expression and Function During Vascular Remodeling:	Host: Dr. Don Menick Sponsor: MCBP Program
Nov. 25, 2004	Thanksgiving
Dec. 2, 2004	John P. Sundberg, DVM, PhD Senior Staff Scientist The Jackson Laboratory Bar Harbor, Maine Title: "Mouse Models for Dermatological Research"	Host: Dr. Alexander Awgulewitsch Sponsor: MCBP Program
Spring 2004
February 5, 2004	Eleanor K. Spicer, Ph.D. Associate Professor Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Post-transcriptional Regulation of the bcl-2 Oncogene
February 12, 2004	Craig C. Beeson, Ph.D. Associate Professor Department of Pharmaceutical Sciences Medical University of South Carolina Charleston, South Carolina Title: Mechanisms for the Coupling of Respiration and Glycolysis
February 19, 2004	Ron Peterson, Ph.D. Fellow, Laboratory Head Integrated Expression Profiling Novartis Institute of Biomedical Research Title: Pharmacogenomic Analysis of rhIL-11 Effects	Host: Dr. Alexander Awgulewitsch Sponsor: MCBP Program
February 26, 2004	Jason D. Morrow, M.D. Profesor of Medicine and Pharmacology Chair, Department of Pharmacology Vanderbilt University School of Medicine Nashville, Tennessee Title: The Isoprostanes - Their Role as Mediators and Markers of Lipid Peroxidation: New Insights and Current Controversies	Host: Dr. Lina Obeid Sponsor: MCBP Program
March 4, 2004	Michael F. Summers, Ph.D. Professor Department of Chemistry and Biochemistry Howard Hughes Medical Institute Scholar University of Maryland Baltimore County Baltimore, Maryland Title: NMR Studies of Retroviral Genome Recognition and Assembly	Host: Dr. Perry Halushka Sponsor: MCBP Program
March 11, 2004	Jerry Hurwitz, Ph.D. Vice Chairman, Sloan-Kettering Institute Memorial Sloan-Kettering Cancer Center New York, New York Title: Studies on Eukaryotic DNA Replication	Host: Dr. Deepak Bastia Sponsor: Biochemistry
March 18, 2004	Richard J. Youle, Ph.D. Section Chief of Biochemistry Surgical Neurology Branch NINDS, NIH Bethesda, Maryland Title: Role of Bcl-2 Family Proteins and Mitochondria Morphology in Apoptosis	Host: Dr. Yi-Te Hsu Sponsor: Biochemistry
March 25, 2004	Ian A. Blair, Ph.D. A.N. Richards Professor of Pharmacology Professor of Chemistry Director, Center for Cancer Pharmacology Scientific Director, Genomics Institute Proteomics Facility University of Pennsylvania School of Medicine Philadelphia, Pennsylvania Title: Cyclooxygenase-Mediated DNA Damage	Host: Dr. Perry Halushka Sponsor: MCBP Program
April 1, 2004	Kenneth D. Philipson, Ph.D. Professor Department of Physiology and Medicine Cardiovascular Research Lab UCLA Los Angeles, California Title: Cardiac Sodium-Calcium Exchange: From Molecule to Mouse	Host: Dr. Don Menick Sponsor: MCBP Program
April 8, 2004	Michael Zasloff, Ph.D. Dean, Research and Translational Science Georgetown University Medical Center Washington, D.C. Title: Antimicrobial Peptides of Animals in Health and Diseases	Host: Dr. Paul Gross Sponsor: Biochemistry
April 15, 2004	NO SEMINAR
April 22, 2004	Christian R. Raetz, M.D., Ph.D. Professor and Chairman Department of Biochemistry Duke University Medical Center Durham, North Carolina Title: Assembly, Secretion and Function of Gram-negative Endotoxin: A Potent Lipid Activator of Innate Immunity	Host: Dr. Yusuf Hannun Sponsor: MCBP Program
April 29, 2004	NO SEMINAR
May 6, 2004	Alfonso Bellacosa, M.D. Human Genetics Program Population Science Division Fox Chase Cancer Center Philadelphia, Pennsylvania Title: Role of the MED1 (MBD4) Gene in DNA Repair and Human Cancer or DNA Repair and Cancer Susceptibility	Host: Dr. Robin Muise-Helmericks Sponsor: MCBP Program
Fall 2003
September 25, 2003	Paul A Marks, M.D. Professor of Medicine Memorial Sloan Kettering Cancer Center New York, New York Title: Histone Deacetylase Inhibitors	Host: Dr. Gary Gilkeson Sponsor: MCBP Program
October 2, 2003	Christopher Davies, Ph.D. Assistant Professor of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Developmental Scholar Award Title: Glycolysis Under Extreme Conditions: A Novel Enzyme in Pyrococcus Furiosus
October 9, 2003	Amar J.S. Klar, Ph.D. Developmental Genetics Section Gene Regulation and Chromosome Biology Laboratory NCI Center fro Cancer Research Frederick, Maryland Title: Two Independent Epigenetic Events Regulate Fission Yeast Mating-type Switching and Silencing	Host: Dr. Deepak Bastia Sponsor: MCBP Program
October 16, 2003	Robert S. Kass, Ph.D. David Hosack Professor of Pharmacology Chair, Department of Pharmacology Center for Neurobiology and Behavior Columbia University New York, New York Title: Clinical and Basic Studies of Inherited Cardiac Arrhythmias: Novel Insight into the Molecular Physiology Pharmacology of Ion Channels in the Heart	Host: Dr. Steve Kubalak Sponsor: MCBP Program
October 23, 2003	Swapan K. Ray, Ph.D. Assistant Professor Department of Neurology Medical University of South Carolina Charleston, South Carolina Title: Experimental Therapeutics for Activation of Apoptosis in Glioblastoma
October 30, 2003	Meenakshi A. Chellaiah, Ph.D. Assistant Professor Oral Cranio Biological Sciences University of Maryland Baltimore, Maryland Title: Molecular Basis of Cytoskeletal Reorganization in Osteoclasts in Response to Integrin avb3 Activation	Host: Dr. Dhan Kuppuswamy Sponsor: MCBP Program
November 6, 2003	TBA
November 13, 2003	M. Rita Young, Ph.D. Professor of Medicine Division of Hematology/Oncology Medical University of South Carolina AOCS, Ralph H. Johnson VA Medical Center Charleston, South Carolina Title: The Role of CD34+ Progenitor Cells in Tumor Progression
November 20, 2003	Howard A. Rockman, M.D. Professor of Medicine Department of Cell Biology and Genetics Duke University Medical Center Durham, North Carolina Title: Novel Insights into Heptahelical Receptor Signaling in the Heart	Host: Dr. Steve Kubalak Sponsor: Cardiovascular Training Grant
November 27, 2003	Thanksgiving
December 4, 2003	TBA
December 11, 2003	Hamid Band, M.D., Ph.D. Professor of Medicine Feinberg School of Medicine Northwestern University Director, Division of Molecular Oncology Evanston Northwestern Healthcare Research Institute Evanston, Illinois Title: Negative Regulation of Tyrosine Kinases by Cb1 Family of Ubiquitin Ligases	Host: Dr. Dennis Watson Sponsor: MCBP Program
Spring 2003
January 16, 2003	Jay A. Tischfield Duncan and Nancy MacMillan Professor of Genetics Chair Department of Genetics Nelson Biological Labs Rutgers University Piscataway, New Jersey Title: Mechanisms of Loss of Heterozygosity in Somatic Cells of Mice and Humans	Host: Dr. Donald R. Menick Sponsor: MCBP Program
January 23, 2003	Cancelled
January 30, 2003	Barry T. Hinton, Ph.D. Professor of Cell Biology University of Virginia School of Medicine Charlottesville, Virginia Title: Testicular Luminal Growth Factors as Regulators of Epididymal Gene Expression	Host: Dr. Demetri Spyropoulos Sponsor: MCBP Program
February 6, 2003	Kuo-Chen Chou, D.Sc., Ph.D. Senior Research Advisor Computer-Aided Drug Discovery Research and Development Pharmacia Corporation Title: Protein Attribute Prediction - A New Branch in Proteomics	Host: Dr. Perry V. Halushka Sponsor: MCBP Program
February 13, 2003	Mark S. Kindy, Ph.D. Admiral Pihl Chair and Professor Department of Physiology and Neuroscience Director of the Stroke Program of MUSC Associate Director, Center on Aging Assoc. Director of the South Carolina Spinal Cord Center Medical University of South Carolina Title: Stroke: Molecular Mechanisms of Disease
February 20, 2003	Developing Scholars Seminar Sergey A. Krupenko, Ph.D. Assistant Professor of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: 10-Formyltetrahydrofolate Dehydrogenase: Structure, Function and its Role in Cellular Proliferation
February 27, 2003	Peter W. Kalivas, Ph.D. Professor and Chair Department of Physiology and Neuroscience Medical University of South Carolina Charleston, South Carolina Title: Addiction: A Pathology in Molecular Mechanisms of Memory
March 6, 2003	Amy Bradshaw, Ph.D. Assistant Professor of Medicine (Cardiology) Medical University of South Carolina Charleston, South Carolina Title: Cell Design of the Extracellular Matrix: Alterations in Collagen Structure and Composition Influence Cell Behavior
March 13, 2003	Spring Break
March 20, 2003	William L. Smith, Ph.D. Professor of Biochemistry Michigan State University East Lansing Michigan Title: Fatty Acid Cyclooxygenase: Structure and Function	Host: Dr. Perry V. Halushka Sponsor: MCBP Program
March 27, 2003	TBA
April 3, 2003	Merry Lindsey, Ph.D. Assistant Professor Department of Surgery Medical University of South Carolina Charleston, South Carolina Title: Identifying MMP-9 Roles Following MI: Elucidating Mechanisms of MMP Function in the Remodeling Myocardium	Host: Dr. Frank Spinale Sponsor: Division of Cardiothoracic Surgery
April 10, 2003	Sherman Weissman, Ph.D. Sterling Professor of Human Genetics Director of Molecular Oncology and Development Boyer Center for Molecular Medicine Yale University New Haven, Connecticut Title: Mammalian Molecular Biology on a Genomic Scale. Three Billion Bases Are Easy and 700 Are Hard	Host: Dr. Depak Bastia
April 17, 2003	Gary Nabel, M.D., Ph.D. Director, VRC National Institutes of Health Bethesda, Maryland Title: How Do Viruses Kill Cells?	Host: Dr. Jim Norris Sponsor: MCBP Program
April 24, 2003	TBA
May 1, 2003	Armen Manoukian, Ph.D. Associate Professor Department of Medical Biophysics Ontario Cancer Institute University of Toronto Toronto, Canada TBA	Host: Dr. Tien Hsu Sponsor: MCBP Program
May 8, 2003	William Dowhan, Ph.D. Professor and John S. Dunn Chair Department of Biochemistry and Molecular Biology, and Microbiology University of Texas-Houston Medical Center Houston, Texas Title: Role of Cardiolipin and Phosphatidylglycerol in Mitochondrial Function	Host: Dr. Yusuf Hannun Sponsor: Biochemistry and Molecular Biology
May 22, 2003	Richard L Proia, Ph.D. Chief, Genetics of Development and Disease Branch NIDDK, National Institutes of Health Bethesda, Maryland Title: Role of Sphingolipids in Signaling by Tyrosine Kinase and G-protein Coupled Receptors	Host: Dr. Yusuf Hannun Sponsor: Biochemistry and Molecular Biology
Fall 2002
September 26, 2002	Daria Mochly-Rosen, Ph.D. Professor and Chief Department of Molecular Pharmacology Stanford University School of Medicine Stanford, California Title: PKC and Cardiac Function: A Tale of Protein-Protein Interactions	Host: Dr. Frank Spinale Sponsor: Cardiothoracic Surgery
October 3, 2002	H. Leighton Grimes, Ph.D. Assistant Professor Institute of Cell Therapeutics University of Louisville Louisville, Kentucky Title GFI1 Oncoprotein: Cell Fate Determination in Lymphopoiesis and Epithelial Malignancy	Host: Robin Muise-Helmericks, PhD Sponsor: MCBP Program
October 17, 2002	Robert G. Gourdie, Ph.D. Associate Professor Department of Cell Biology and Anatomy Medical University of South Carolina Charleston, South Carolina Title: Conducting the Heart Beat: Orchestrating Development of Specialized Pathways for Propagation of Cardiac Action Potential
October 24, 2002	Donald M. Bers, Ph.D. Professor and Chair Department of Physiology Loyola University, Stritch School of Medicine Chicago, Illinois Title: Sodium and Calcium in Cardiac Myocytes: Involvement in Contractile Function and Arrhythmogenesis in Heart Failure	Host: Dr. Donald Menick Sponsor: MCBP Program
October 31, 2002	David L. Williams, Ph.D. Professor of Surgery James H. Quillen College of Medicine East Tennessee State University Johnson City, Tennessee Title: Potential Role of the Phosphoinositide 3-Kinase Signaling Pathway in the Response to Polymicrobial Sepsis and Septic Shock	Host: Dr. James A. Cook Sponsor: MCBP Program
November 7, 2002	CANCELLED TO BE RESCHEDULED	Dr. Frank Spinale Dr. Rupak D. Mukherjee Cardiothoracic Surgery
November 14, 2002	John D. Hildebrandt, Ph.D. Professor and Chair Department of Cell and Molecular Pharmacology Medical University of South Carolina Charleston, South Carolina Title: Generation and Function of G Protein Subunit Diversity	Host: Dr. Shailesh Patel Sponsor: Department of Medicine and MCBP Program
November 21, 2002	Lei Yu, Ph.D. Professor Department of Cell Biology, Neurobiology, and Anatomy University of Cincinnati College of Medicine Cincinnati, Ohio Title: The Opioid System and Its Role in Physiological Modulation	Host: Dr. Donald Menick Sponsor: MCBP Program
November 28, 2002	Thanksgiving - NO SEMINAR
December 5, 2002	William M. Chilian, Ph.D. TBA	Host: Dr. George Cooper Sponsor: Cardiology Division/Department of Medicine MCBP Program
December 12, 2002	David R. Clemmons, M.D. Professor of Medicine Sarah Graham Kenan Professor of Medicine Chief, Division of Endocrinology and Metabolism University of North Carolina Chapel Hill, North Carolina Title: Cooperative Interactions Among Three Integral Membrane Proteins in Controlling IGF-1 Receptor Activation	Host: Dr. Steven A Rosenzweig Sponsor: MCBP Program
Spring 2002
January 10, 2002	Robert W. Thompson, M.D. Professor of Surgery and Cell Biology Washington University School of Medicine St. Louis, Missouri Title: Matrix Metalloproteinases and Vascular Remodeling	Host: Dr. Frank Spinale Sponsor: Cardiothoracic Surgery
January 17, 2002	Hiroko Hama, Ph.D. Assistant Professor of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Phosphoinositide Regulation of Membrane Trafficking in Saccharomyces Cerevisiae
January 24, 2002	CANCELLED
January 31, 2002	Fernando R. Cabral, Ph.D. Associate Professor Department of Integrative Biology and Pharmacology University of Texas Medical School Houston, Texas Title: The Role of Microtubule Assembly in Resistance to Cancer Drugs	Host: Dr. George Cooper Sponsor: Cardiothoracic Surgery
February 7, 2002	Deepak Bastia, Ph.D. Professor Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Mechanism of Initiation and Termination of DNA Replication in Bacteria and Yeast
February 14, 2002	Steven A Rosenzweig, Ph.D. Professor Department of Cell and Molecular Pharmacology Medical University of South Carolina Charleston, South Carolina Title: Targeting the Insulin-like Growth Factor System for the Development of Novel Therapeutics
February 21, 2002	Joyce J. Repa, Ph.D. Assistant Professor Departments of Physiology and Internal Medicine Touchstone Center for Diabetes Research University of Texas Southwestern Medical Center Dallas, Texas Title: Nuclear Orphan Receptor Regulation of Cholesterol and Bile Acid Metabolism	Host: Dr. Shailesh Patel Sponsor: Department of Medicine and MCBP Program
February 28, 2002	John M. Arthur, M.D., Ph.D. Associate Professor of Medicine (Nephrology) Medical University of South Carolina Charleston, South Carolina Title: Proteomics: Principles and Applications
March 7, 2002	Frank J. Rauscher, III, Ph.D. Professor and Chairman The Molecular Genetics Program Deputy Director The Wistar Institute Cancer Center Philadelphia, Pennsylvania Title: Functions of the KRAB Domain Superfamily of Zinc-Finger Repressors: A Paradigm for Coordinating Histone De-acetylation, Methylation and Heterochromatin Formation?	Host: Dr. Dennis Watson Sponsor: MCBP Program
March 14, 2002	Basilia Zingarelli, M.D., Ph.D. Assistant Professor Division of Critical Care Medicine University of Cincinnati Children's Hospital Cincinnati, Ohio Title: Nuclear Control of Inflammation: A Role of Poly (ADP-ribosyl)ation	Host: Jim Cook Sponsor: Department of Physiology and MCBP Program
March 21, 2002	Gerardo R. Vasta, Ph.D. Professor Center of Marine Biotechnology University of Maryland Biotechnology Institute Title: Innate Immunity in Invertebrates: Self/Non-Self Recognition by the Host, and Parasite Adaptations for Entry and Survival
March 28, 2002	Jon Y. Takemoto, Ph.D. Professor of Biology Utah State University Logan, Utah Title: Novel Antifungal Action by Pseudomonad Cyclic Lipodepsipeptides	Host: Dr. Hiroko Hama Sponsor: MCBP Program and Department of Biochemistry
April 4, 2002	Gregory W. Warr, Ph.D. Professor Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Transcriptional Enhancers and the Evolution of Immunoglobulin Genes
April 11, 2002	CANCELLED
April 18, 2002	David C. Gadsby Director Lab Cardiac and Membrane Physiology Rockefeller University New York, New York Title: Control of CFTR channel opening and closing by ATP binding and hydrolysis	Host: Dr. Don Menick Sponsor: MCBP Program
April 25, 2002	No Seminar
May 2, 2002	M. Elizabeth Fini New England Eye Center Tufts University Boston, Massachusetts Title: New Roles for Matrix Metalloproteinase Gelatinase B.	Host: Dr. Frank Spinale Sponsor: Cardiothoracic Surgery
Fall 2001
September 13, 2001	Robert W. Thompson, M.D. Professor of Surgery and Cell Biology Washington University School of Medicine St. Louis, Missouri Title: New Insights into Vascular Aneurysmal Disease: Translating Basic Discoveries into Therapeutic Modalities	Host: Frank Spinale, M.D., Ph.D. Sponsor: Cardiothoracic Surgery
September 20, 2001	Besim Ogretmen, Ph.D. Assistant Professor of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Molecular Mechanisms of the Regulation of Telomerase by Ceramide in Human Lung Cancer Cells
September 27, 2001	Rick G. Schnellman, Ph.D. Professor and Chair Department of Pharmaceutical Sciences Medical University of South Carolina Charleston, South Carolina Title: Calcium and Calpains in the Inititation and Progression of Cell Death
October 4, 2001	Jeffrey Molkentin, Ph.D. Assistant Professor Children's Hospital Medical Center Cincinnati, Ohio Title: Signal Transduction Pathways Controlling Heart Maturation and Hypertrophy	Host: Frank Spinale, M.D., Ph.D. Sponsor: Cardiothoracic Surgery
October 11, 2001	Cancelled
October 18, 2001	Salih J. Wakil, Ph.D. Professor and Chairman Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston, Texas Title: The Role of Acetyl-CoA Carboxylase 2 in Fatty Acid Metabolism and Energy Homeostasis	Host: Yusuf Hannun, M.D. Sponsor: Department of Biochemistry and Molecular Biology
October 25, 2001	Michael B. O'Connor, Ph.D. Associate Investigator Department of Genetics, Cell Biology and Development HHMI, University of Minnesota Minneapolis, Minnesota Title: BMP Signaling Regulates Synapse Development and Function at the Neuromuscular Junction in Drosophila	Host: Tien Hsu, Ph.D. Sponsor: MCBP Program
November 1, 2001	Frank J. Rauscher, III, Ph.D. Professor and Chairman The Molecular Genetics Program Deputy Director The Wistar Institute Cancer Center Philadelphia, Pennsylvania Title: Functions of the KRAB-domain Superfamily of Zinc-Finger Repressors: A Paradigm for Coordinating Histone De-acetylation, Methylation and Heterochromatin Formation	Host: Dennis Watson, Ph.D. Sponsor: MCBP Program
November 8, 2001	Timothy Hla, Ph.D. Professor of Physiology, and Genetics and Developmental Biology Director, Center for Vascular Biology University of Connecticut School of Medicine Farmington, Connecticut Title: Sphingosine 1-phosphate as an Angiogenic Modulator	Host: Lina Obeid, M.D.
November 15, 2001	Myles C. Cabot, Ph.D. Chief, Breast Cancer Research Program John Wayne Cancer Institute Santa Monica, California Title: Targeting Ceramide Metabolism as an Approach to Cancer Treatment	Host: Yusuf Hannun, M.D.
November 22, 2001	Thanksgiving
November 29, 2001	Simon Conway, Ph.D. Associate Professor Institute of Molecular Medicine and Genetics Medical College of Georgia Augusta, Georgia Title: Molecular Analysis of Embryonic Heart Development	Host: Donald R. Menick, Ph.D. Sponsor: MCBP Program
December 6, 2001	Arturo Casadevall, M.D, Ph.D. Professor, Department of Microbiology And Immunology Albert Einstein College of Medicine Yashiva University Bronx, New York Title: Cryptococcus Neoformans: A Pathogen in Black and White	Host: Maurizio Del Poeta, M.D. Sponsor: Department of Biochemistry and Molecular Biology
Spring 2001
Jan. 18, 2001	Leslie Leinwand, Ph.D. Professor of Molecular and Cell Developmental Biology University of Colorado Boulder, Colorado Title: Molecular Mechanisms of Hypertrophy and Failure	Host: Dr. George Cooper Sponsor: MCBP Program The Adult Cardiology Division
Jan. 25, 2001	Masashi Yanagisawa, M.D., Ph.D. Investigator & Professor Department of Molecular Genetics Howard Hughes Medical Institute University of Texas Southwestern Medical Institute Dallas, Texas TBA	Host: Dr. Shailesh Patel
Feb. 1, 2001	James T. McLaughlin, Ph.D. Assistant Professor of Physiology and Neuroscience Medical University of South Carolina Charleston, South Carolina Title: Exploring Specificity of Calcium Channel Signaling in Neuroendocrine Cells
Feb. 8, 2001	L. Courtney Smith, Ph.D. Assistant Professor of Biology and Genetics Department of Biological Sciences Institute of Biomedical Sciences, Programs in Genetics & Immunology George Washington University Washington, D.C. Title: The Ancestral Innate Immune System in Sea Urchins	Hosts: Matthew Jenny Dr. Greg War
Feb. 15, 2001	Linda C. McPhail, Ph.D. Professor, Department of Biochemistry Wake Forest University School of Medicine Winston-Salem, North Carolina TBA	Host: D. Yusuf Hannun Sponsor: MCBP Program Dept. of Biochemistry and Molecular Biology
Feb. 22, 2001	James E. Hall, Ph.D. Professor, Department of Physiology & Biophysics University of California - Irvine Irvine, California TBA	Host: Dr. Kevin Schey
March 1, 2001	John H. Exton, M.D., Ph.D. Professor, Departments of Molecular Physiology, Biophysics, and Pharmacology Howard Hughes Medical Institute Vanderbilt University Nashville, Tennessee Title: Structure, Function, and Regulation of MAP Kinase Pathways	Host: Dr. Yusuf Hannun Sponsor: MCBP Program Dept. of Biochemistry and Molecular Biology
March 8, 2001	Melanie H. Cobb, Ph.D. Professor, Department of Pharmacology University of Texas Southwestern Medical Center Dallas, Texas Title: Structure, Function, and Regulation of MAP Kinase Pathways	Dr. Donald R. Menick
March 15, 2001	SPRING BREAK
March 22, 2001	Robin Muise-Helmericks, Ph.D. Assistant Professor of Cell Biology and Anatomy Hollings Cancer Institute Medical University of South Carolina Charleston, South Carolina Title: Functional Role of Akt and Ets 1 in Angiogenesis
March 29, 2001	Roger H. Reeves, Ph.D. Professor, Department of Physiology The Johns Hopkins University School of Medicine Baltimore, Maryland Title: Tales from the MICU (Mouse Intensive Care Unit): QTL Mapping and the inflammatory Response	Host: Dr. Dennis Watson
April 5, 2001	Marsha Rosner, Ph.D. Director, and Charles B. Huggins Professor Ben May Institute for Cancer Research University of Chicago Chicago, Illinois Title: Specificity in MAP Kinase Signaling Pathways	Host: Dr. Steve Rosensweig
April 12, 2001	Thoru Pederson, Ph.D. President and Director Worcester Foundation for Biomedical Research Shrewsbury, Massachusetts TBA	Host: Dr. Paul McDermott Sponsor: MCBP Program The Adult Cardiology Division
April 19, 2001	David K. Perry, Ph.D. Instructor of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Regulation of De Novo Ceramide in Cellular Stress
Fall 2000
Sep. 14, 2000	James Cook, Ph.D. Professor of Physiology and Neuroscience Medical University of South Carolina Charleston, South Carolina Title: Endotoxin Signal Transduction Pathways and Their Alterations in Endotoxin Tolerance
Sep. 21, 2000	Joseph S. Janicke, Ph.D. Professor, Department of Anatomy, Physiology & Pharmacology Auburn University Auburn, Alabama Title: Myocardial Collagen Matrix Regulation During Ventricular Remodeling: The Role of the Cardiac Mast Cell	Host: Dr. Michael R. Zile Sponsor: MCBP Program
Sep. 28, 2000	Neil Osheroff, Ph.D. Professor , Department of Biochemistry Vanderbilt University School of Medicine Nashville, Tennessee Title: The DNA Cleavage Reaction of Topoisomerase II, Dr. Jekyll or Mr. Hyde?	Host: Dr. Dan Fernandes Sponsor: MCBP Program
Oct. 5, 2000	Jacqueline F McGinty, Ph.D. Professor of Physiology and Neuroscience Medical University of South Carolina Charleston, South Carolina Title: Brain Mechanisms Underlying Drug Abuse
Oct. 12, 2000	Denise Montell, Ph.D. Associate Professor Department of Biological Chemistry Johns Hopkins School of Medicine Baltimore, Maryland Title: Changes in Gene Expression, Cell Adhesion and Actin Organization in the Developmental Control of Cell Migration	Host: Dr. Tien Hsu Sponsor: MCBP Program
Oct. 19, 2000	Rudolph Juliano, Ph.D. Professor and Chair Department of Pharmacology University of North Carolina Chapel Hill, North Carolina Title: Integrins and Signal Transduction	Host: Dr. Donald Menick Sponsor: MCBP Program
Oct. 26, 2000	Donald R. Menick, Ph.D. Associate Professor of Medicine, and Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Regulation of Gene Expression in Cardiac Hypertrophy and Failure
Nov. 2, 2000	Lynn M. Matrisian, Ph.D. Professor and Chair Department of Cancer Biology Vanderbilt University Nashville, Tennessee Title: Matrix Metalloproteinases in Normal and Neoplastic Processes	Host: Dr. Frank Spinale Sponsor: MCBP Program
Nov. 9, 2000	Sergey Krupenko, Ph.D. Assistant Professor of Biochemistry and Molecular Biology Medical University of South Carolina Charleston, South Carolina Title: Structure/Function Studies of a Major Folate Enzyme
Nov. 16, 2000	Peter Nelson, Ph.D. Assistant Member Division of Human Biology Department of Molecular Biotechnology Fred Hitchinson Cancer Research Center University of Washington Seattle, Washington Title: Genome and Proteome Approaches for Charachterizing the Prostate Androgen-Response Program	Host: Dr. Dennis Watson Sponsor: MCBP Program
Nov. 30, 2000	Charles N. Serhan, Ph.D. Director, Center for Experimental Therapeutics and Reperfusion Injury Professor of Anaesthesia (Biochemistry and Molecular Pharmacology) Brigham and Women's Hospital/Harvard Medical School Boston, Massachusetts Title: Novel Arrays of Lipid Signals in Anti-inflammation	Host: Dr. Yusuf A. Hannun Sponsor: MCBP Program
Dec. 7, 2000	Walter J. Koch, Ph.D. Associate Professor Department of Surgery and Pharmacology Duke University Medical Center Durham, North Carolina Title: G Protein-coupled Receptor Kinases in the Cardiovascular System: Lessons Learned from Transgenic Mice	Host: Ashley Smithwick Sponsor: MCBP Program

Monday Noon Seminar Series Calendar
502 - Basic Science Building

FAll 2006-Spring 2007

FALL 2006		SPRING 2007
Sept. 4 (Labor Day)	No seminar	Jan 15 (MLK Day)	No seminar
Sept. 11		January 22	Loretta Hoover
			Maria Vizcaino
Sept. 18	Jennifer Konopa-Mulligan	Jan 29	Colleen Bryan
	Jennifer Yordy		Meagan Mollenhauer
Sept 25	No Seminar	Feb 5	Liz Grant Burton
			Jocelyn Flanary
Oct. 2	Julie Woolworth	Feb 12	Christina Grek
			Shawn Polson
Oct. 9	Rany Abdallah	Feb 19	Tom Mullen
	Arindam Saha		Rebecca Johnston
Oct. 16	Wes Jackson	Feb 26	Chris Gault
	Angela Ghatneka		Jessica Shockey
Oct. 23	Michael O'Quinn	March 5	Hazitha Samuel
	Erin Morris		Stephanie Brunelle
Oct. 30 (SRD week)	Elaine Wirrig Kelli Margot	March 12	Spring Break No Seminar
Nov 6	Adrian Grimes	March 19	Tara Burns
	Phil Moshchella		Tod Leighfield
Nov 13	Emily Monroe	March 26	Brian Snarr
	Kristie Lidie		Youssef Zaidan
Nov 20	Jonathan Butler	April 2	Millie Embree
	Blake Ellis		Chris Potter
Nov 27	Matt Mains	April 9	Bobbie Lyon
	Jason Guichard		John Svenson
Dec 4	Ben Neely	April 16	Khaled Moussawi
	Nathan Pruett		Anand Shunmugavel
Dec 11	For emergency seminar only	April 23	Matt Rhett
			Arun Palanisamy
		April 30	For emergency seminar only

Autumn 2004		Spring 2005
Aug 30	No seminar Sign-up only	Jan 10	Peko Tsuji Tracey Schock

Sep 6	LABOR DAY	Jan 17 (MLK)	We will use this day only if we are running out of slots

Sept 13		Jan 24	Chris Johnson Megan Kibbey

Sept 20	Millie Embree	Feb 7	Peter Wieckowski Ramandeep Rattan

Sept 27		Feb 14	Laura Spruill Lena Heung

Oct 4	MUSC- Townhall meeting In BSB 100	Feb 21	Frank Bartel Christy Kappler

Oct 11		Mar 7	Gregor Krings Shantae Jenkins

Oct 18		Mar 14	SPRING BREAK

Oct 25	Jessica Petersen Tarek Taha	Mar 21	David Arrington Erin Egan

Nov 1	Jessica Shockey Leslie Wooten	Mar 28	Anne Deschamps Kevin Orwig

Nov 8 (Mon after SRD)	Jason Guichard Adrian Grimes	April 4	Shawn Polson Kristie Lidie

Nov 15 (thnxgiv wk)	Mara Lennard Matt Jenny	April 11	Sara Polson John Svensen

Nov 22	Amanda Galloway Juan C. Varela	April 18	Jonathan Mitchell Richard Peterson (?)

Nov 29	Michelle Hsia Joy Van Nostrand	April 25	Javier Robalino Arun Palanisamy

Dec 6	Eric Sribnick Ratna Prasad

Spring 2002

January	14	Mark Pilgrim
	21	Jeff Jones
	28	Melissa Fraser
February	4	Ron Feldman
	11	Benjamin Pettus
	18	Michelle Crosby
	25	Kevin Becker
March	4	Laura Columbo
	11	Spring Break
	18	Paula Acierno
	25	Vijay Rao
April	1	David McLean
	8	Nicole Redmond
	15	Christopher Willey
	22	Josh Hubbard
	29

Fall 2001

August	27	Eric Grund	Yair Adereth		Amanda LaRue
September	10	Stephen Gee	Matthew Jenny		Andrew Whitlock
	17	Christiana Kappler	Ravinder Pannu		Jeannette Weiner
	24	Xingjun Wu	Mark Slomiany		Megan Kibbey
October	1	Robert Bowers		Michael Janech
	8	Kerin McCormack		Beth Neilsen
	15	Alan Frey (Kroc Lecture; hosted by Steve Tomlinson)
	22	Sean Norman		Ashley Smithwick
	29	Robert Smith		Brian Giles
November	5	Christopher Crosby
	12	Jeannie Chapman
	19	Frank Bartel
	26	Elizabeth Chesterman
December	3	Kevin Orwig

Information For

University

Medical

Help & Contacts

MCBP Past Seminars

January

14

Mark Pilgrim

21

Jeff Jones

28

Melissa Fraser

February

4

Ron Feldman

11

Benjamin Pettus

18

Michelle Crosby

25

Kevin Becker

March

4

Laura Columbo

11

Spring Break

18

Paula Acierno

25

Vijay Rao

April

1

David McLean

8

Nicole Redmond

15

Christopher Willey

22

Josh Hubbard

29

August

27

Eric Grund

Yair Adereth

Amanda LaRue

September

10

Stephen Gee

Matthew Jenny

Andrew Whitlock

17

Christiana Kappler

Ravinder Pannu

Jeannette Weiner

24

Xingjun Wu

Mark Slomiany

Megan Kibbey

October

1

Robert Bowers

Michael Janech

8

Kerin McCormack

Beth Neilsen

15

Alan Frey (Kroc Lecture; hosted by Steve Tomlinson)

22

Sean Norman

Ashley Smithwick

29

Robert Smith

Brian Giles

November

5

Christopher Crosby

12

Jeannie Chapman

19

Frank Bartel