College of Graduate Studies
Foundations of Biomedical Sciences (CGS 701 and 702)
Adam J. Smolka, Ph.D., Course Director
22 August, 2012 to 8 March, 2013
Monday, Tuesday, Wednesday 9:00 am-12:00 pm
Room 435, Basic Science Building
A guiding principle of Foundations of Biomedical Sciences is that students must develop depth of knowledge, and an understanding of how to extend that knowledge by asking relevant questions and designing experiments that give solid answers. Just as importantly, students must acquire skill in articulate, clear discussion of scientific principles and data. Thus, students and faculty are encouraged to develop scientific interchange through interactive discussion-based forums that are integrated into all eight Units. Full student participation is essential; all students are required to attend all classes, and absences must be cleared through the appropriate Unit Leader.
Foundations of Biomedical Sciences comprises five Units in the fall semester, and three Units in the first half of the spring semester. The fall Units (CGS 701) address the basic chemical and molecular mechanisms of biology, encompassing protein and nucleic acid structure and function, membrane bioenergetics and functional metabolic compartments, receptor signal transduction and coupling to intracellular pathways and consequent regulation of gene expression at transcriptional, translational and post-translational levels. The Spring semester Units (CGS 702) extend molecular understanding to cellular, tissue and organismal biology levels, from a consideration of cell structure and functions, through mechanisms of disease and defense, and finally to appreciation of integrated physiological systems.
Merit grades are assigned for Foundations of Biomedical Sciences CGS 701 and 702. The final grade for each Foundations of Biomedical Sciences course is the average of the Unit scores, and is predicated on completion of all elements of that course. Each Unit grade is derived from performance on graded In-Unit assignments, quizzes and interactive discussion-based forums, and from closed-book, in-class exams. All exams, tests, quizzes, written work, laboratory work and research activities at MUSC are conducted under the Honor Code, detailed at www.musc.edu/honorcode/honorcode.html.