Department of Microbiology and Immunology
Janardan Pandey
Professor
Microbiology & Immunology
Education
1972 Ph.D., University of Wisconsin, Madison
Contact Info
pandeyj@musc.edu
Tel: 843-792-4360
BSB 753A-B
Research Interests
The primary focus of my laboratory is directed towards understanding the mechanisms underlying the involvement of immunoglobulin Fc (GM) and Fcgamma receptor genes in immunity to various malignant and infectious diseases. These studies are supported in part by grants and contracts from the National Institutes of Health and the Department of Defense.
Recent Publications | Additional Publications
Pandey JP, Morais CG, Fontes CJF, Braga EM. Immunoglobulin GM 3 23 5,13,14 phenotype is strongly associated with IgG1 antibody responses to Plasmodium vivax vaccine candidate antigens PvMSP1-19 and PvAMA1. Malar J 2010; 9:229.
Pandey JP. Immunoglobulin GM genes as functional risk and protective factors for the development of Alzheimer’s disease. J Alzheimer’s Dis 2009; 17:753-756.
Pandey JP, Nietert PJ, Klaamas K, Kurtenkov O. A genetic variant of immunoglobulin g2 is strongly associated with natural immunity to mucin 1 in patients with breast cancer. Cancer Immunol Immunother 2009; 58:2025-2029.
Pandey JP, Namboodiri AM, Luo Y, Wu Y, Elston RC, Thomas DL, Rosen HR, Goedert JJ. Genetic markers of IgG influence the outcome of infection with hepatitis C virus. J Infect Dis 2008; 198:1334-1336.
Pandey JP, Nietert PJ, Mensdorff-Pouilly S, Klaamas K, Kurtenkov O. Immunoglobulin allotypes influence antibody responses to mucin 1 in patients with gastric cancer. Cancer Res 2008; 68:4442-4446.
Namboodiri AM, Nietert PJ, Pandey JP. Hepatitis C virus core protein discriminates between the two IgG2 allotypes. Viral Immunol 2008; 21:273-276.
Research Support
Title: Epistatic Effects of FcgR and Fc (GM) Genes in Breast Cancer
Agency: Department of Defense
Role: PI
Funding Period: 6/01/2008 - 5/31/2011
Title: Genetic Regulation of Humoral Immunity to HIV and Ad5 Epitopes
Agency: NIH
Role: PI of the subcontract
Funding Period: 6/1/2009 - 5/31/2011
Title: Racially Associated Immunoglobulin G and Fcgamma Receptor Genes and Humoral Immunity to Mucin 1 in Prostate Cancer
Agency: Department of Defense
Role: PI
Funding Period: 6/15/2010 - 6/14/2013