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Department of Microbiology and Immunology

Microbiology & Immunology Courses 2015-2016

MBIM-623G. Microbiology for Dental Students. Microbiology is a core course in the dental curriculum that is intended to foster a knowledge base and understanding of the fundamentals of bacterial physiology and genetics; clinical bacteriology, virology, parasitology and mycology; antimicrobial therapy; asepsis in dentistry; and infection control. The primary goals of the course are to explore the relationship between the physiology of medically important microbes to the pathobiological sequelae of human-microbial interactions, with particular reference to the role of oral microbes in human disease. Emphasis is placed on the study of oral ecology, dental caries, periodontal disease, hepatitis and AIDS. Laboratory instruction includes problem based, small group exercises in microbiology, with specific sections on oral flora and aseptic techniques. 4 s.h. (Schmidt) Spring.

MBIM-725. Virology. This course will introduce principles of virology to advanced microbiology students. The key areas to be covered include the unique features of replication of RNA and DNA viruses, the uses of viruses as vectors, and elements of viral pathogenicity. The material will be presented in a number of formats including lectures by faculty, written papers, oral presentations by students, and discussion of current and seminal literature. 3 s.h. (Kasman, Sutkowski, team) Spring or Fall Alternate Years.

MBIM-735. Molecular & Cellular Basis of Inflammation & Immunity. This course represents an intensive and in-depth study of the areas of cellular immunology, immunogenetics, clinical immunology, and the immunobiology of tumor development. Each area will be presented with the intent of developing a sound understanding of experimental and theoretical observations. Emphasis will be placed on the most current research involving sophisticated methodology. 4 s.h. (Atkinson) Fall/Spring. 

MBIM-738. Introduction to Microbiology and Immunology Methods. This is an introductory research methods course with three goals:(1) to provide students with the planning and mathematical skills to correctly and confidently perform common microbiological and immunological laboratory techniques and collect the results, (2) to present adequate theoretical information about the techniques to enable students to critically appraise results presented in published articles, (3) to teach students how to interpret a methods section a published article such that they can write an adequate protocol for themselves and anyone wishing to repeat their work. There is no wet lab associated with this course. Class time will include approximately 1/3 lecture and 2/3 group active-learning activities. 4 s.h. (Kasman) Fall. 

MBIM-742. Advanced Microbiology. The course will present in-depth perspectives on the agents responsible for the major bacterial, viral and parasitic-induced diseases. Emphasis will be placed on current research and new insights gained into the biochemistry, molecular biology and immunology of these organisms. 4 s.h. (Schmidt, May, team) Fall Alternate Years.

MBIM-770. Seminar. Participation of graduate students in this course is mandatory. Guest speakers supplement the regular program. Each graduate student gives at least one seminar yearly. Pass/Fail 1 s.h. (Haque) Fall/Spring.

MBIM-772. Environmental Microbiology. The course emphasizes fundamental microbiological principles as they apply to the environment. Its main goal is to introduce the student to the concepts of microbial diversity and evolution, microbial metabolism and catalysis in the biodegradation and synthesis of natural and man-made compounds, the microbial role in biogeochemical cycling, and the interactions of microbes with the physical environment and with other organisms related to the application of microbiological approaches to problems which exist in today’s environment. The course should prepare the student interested in environmental problems and issues with the necessary practical information to make sound judgments in assessing meaningful solutions and the role microorganisms play in those processes. 3 s.h. (May) Fall/Spring. 

MBIM-775. Special Topics in Microbiology and Immunology. This elective course will provide continuous update in immunology to those students who have completed Basic and Advanced Immunology and taken their qualifying examination. It will be a seminar course during which the students will meet with the instructors for two hours a week over a semester to discuss the most recent publications and the new insights they give. To ensure a broad coverage, any faculty in Immunology and Microbiology may suggest a topic to be discussed. Prerequisite: MBIM-735 or permission of instructor. 2 s.h. (Schmidt, Kasman) Fall/Spring. 

MBIM-776. Special Projects in Immunology and Microbiology. Individual faculty accept limited numbers of students to pursue a “small” research project. Intended for those students desiring research experience but open to those who would pursue relevant projects of their own design. Prerequisite: permission of instructor. Variable s.h. Fall/Spring.

MBIM-779. Immunogenetics. Initial lectures will review the fundamental principles of genetics. The principle focus of the course will be the genetics of human MHC and immunoglobulin allotypes. Major blood genes will also be discussed. Statistical methods employed in delineating the genetic contribution to human diseases will be reviewed. 2 s.h. (Pandey) Fall. 

MBIM-786. Cancer Immunotherapy Lessons. (K12 Scholars Program.) This course will combine didactic lectures with participation in mock study sections. The first 3 weeks of class will be lecture and the remaining 12 weeks will be used to review and critique past grant proposals related to cancer immunotherapy recently submitted by principal investigators at MUSC. Students will also attend the monthly meetings of the Cancer Immunology and Immunotherapy (CII) program faculty (4 meetings during the semester) and submit a 1 page written summary and response for each. 2 s.h. (Li) Fall/Spring.

MBIM-788. Spring Selective: Immunobiology. Intensive 7-week introductory immunology course for graduate students in lecture format, utilizing Janeway’s Immunobiology as a textbook. Emphasis is on understanding molecular mechanisms resulting in immunity, and experimental methods for testing and discovering these mechanisms. **(not for advanced credit if taken as part of the PhD first year curriculum). 3 s.h. (Atkinson) Spring.

MBIM-856. Critical Literature Review in Inflammation and Immunity. Course is a formalized, refereed Journal Club focused on topics of general interest in Microbiology and Immunology. Mandatory for PhD candidates in Microbiology and Immunology. (Sutkowski, Rubinstein) 1 s.h. Fall/Spring.

MBIM-970. Research. Variable s.h.

MBIM-980. Thesis. Variable s.h.

MBIM-990. Dissertation. Variable s.h.

M&I Students are also free to take advanced courses offered by other departments, provided the courses are approved for advanced credit by the student’s Advisory Committee.

Microbiology & Immunology courses offered by other departments

CFSB-624. Oral ImmunoBiology. Oral Immunology-Oral Biology. Basic and clinical aspects of immunology are oriented toward oral biology with emphasis placed on salivary secretions, dental plaque, dental caries, the mucosal immune response, gingival crevicular fluid, periodontal disease and the acquired immuno-deficiency syndrome (AIDS). Laboratory demonstrations include a variety of immunological techniques used in research and diagnostic laboratories. Students are required to report on several manuscripts, which they choose from recent dental literature in the area of oral biology and oral immunology. In addition, students share this information in small group discussion. Merit graded. 4.0 s.h. Course director: Caroline Westwater Ph.D. Spring.

MCBP-802. Advanced Oral Microbiology & Immunology.  This course will teach microbiological and immunological concepts through in-depth study of infectious diseases. Emphasis will be placed on the major bacterial, fungal, and viral infections affecting the oral cavity and associated craniofacial structures. Course topics will focus on the pathogen, the host response to the pathogen, and strategies used to prevent or treat these diseases. Students will also be introduced to topics such as biofilm formation, quorum sensing, and the oral-systemic disease connection. Classes will include lecture and primary literature analysis. Student performance will be assessed by problem solving exercises, presentation of assigned paper(s), and exams. Merit graded. 3.0 s.h. Course director: Caroline Westwater Ph.D. Spring or Fall Alternate Years.

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