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Department of Microbiology and Immunology

Courses

Microbiology and Immunology Course Selection

Courses are available for advanced credit unless noted (**):

MBIM-623G. Microbiology for Dental Students.  Microbiology is a core course in the dental curriculum that is intended to foster a knowledge base and understanding of the fundamentals of bacterial physiology and genetics; clinical bacteriology, virology, parasitology and mycology; antimicrobial therapy; asepsis in dentistry; and infection control. The primary goals of the course are to explore the relationship between the physiology of medically important microbes to the pathobiological sequelae of human-microbial interactions, with particular reference to the role of oral microbes in human disease. Emphasis is placed on the study of oral ecology, dental caries, periodontal disease, hepatitis and AIDS. Laboratory instruction includes problem based, small group exercises in microbiology, with specific sections on oral flora and aseptic techniques. 4 hr. Spring (Schmidt).

MBIM-725. Virology. This course will introduce principles of virology to advanced microbiology students. The key areas to be covered include the unique features of replication of RNA and DNA viruses, the uses of viruses as vectors, and elements of viral pathogenicity. The material will be presented in a number of formats including lectures by faculty, written papers, oral presentations by students, and discussion of current and seminal literature. 2 hr. Spring (alternate years) (Faculty). Minimum enrollment, 4.

MBIM-731. Molecular and Cellular Basis of Inflammation and Immunity (formerly Advanced Topics in Immunology).  This course represents an intensive and in-depth study of the areas of cellular immunology, immunogenetics, clinical immunology, and the immunobiology of tumor development. Each area will be presented with the intent of developing a sound understanding of experimental and theoretical observations. Emphasis will be placed on the most current research involving sophisticated methodology. 4 hr. Spring (Atkinson). Minimum enrollment, 4.

MBIM-779. Immunogenetics. Initial lectures will review the fundamental principles of genetics. The principal focus of the course will be the genetics of human MHC and immunoglobulin allotypes. Major blood group genes will also be discussed. Statistical methods employed in delineating the genetic contribution to human diseases will be reviewed. 2 hr. Spring (Pandey). Minimum enrollment, 4.

MBIM-772. Environmental Microbiology. This course emphasizes fundamental microbiological principles as they apply to the environment. Its main goal to introduce the student to the concepts of microbial diversity and evolution, microbial metabolism and catalysis in the biodegradation and synthesis of natural and man-made compounds, the microbial role in biogeochemical cycling, and the interactions of microbes with the physical environment and with other organisms related to the application of microbiological approaches to problems which exist in today's environment. This course also emphasizes real world pollution problems that can be addressed biologically. Biochemical and genetic mechanisms of biodegradation of aromatic and aliphatic compounds, chlorinated compounds, nitroaromatics, and hydrocarbons will be explored. In addition the microbiology of activated sludge, anaerobic digestion, composting, and other liquid, air, and solid phase waste treatment processes will be developed in this course. The course should prepare the student interested in environmental problems and issues with the necessary practical information to make sound judgments in assessing meaningful solutions and the role microorganisms play in those processes. 3 hr. Spring (May). Minimum enrollment, 4.

MBIM-775. Special Topics in Microbiology and Immunology. This elective course provides continuous updates in microbiology and immunology. It is seminar course during which the students will meet with the instructor for two hours a week over a semester to discuss the most recent publications and the new insights they give. To ensure a broad coverage, any faculty in Immunology and Microbiology may suggest a topic to be discussed.Fall/Spring (Faculty).

MBIM-742. Advanced Microbiology. The course will present in depth perspectives on the agents responsible for the major bacterial, viral and parasitic-induced diseases. Emphasis will be placed on current research and new insights gained into the biochemistry, molecular biology and immunology of these organisms. 4 hr. Fall (May and Schmidt). Minimum enrollment, 4.

MBIM-785. Spring Selective: Emerging Infectious Diseases.  This course will teach basic immunological and microbiological concepts through in-depth study of six microorganisms responsible for emerging or epidemic infectious diseases. Each week will focus on the biology, natural history, pathology and immunology associated with one pathogen. Pathogens covered will include avian influenza, tuberculosis, Ebola/Marburg virus, methicillin resistant Staph. aureus, SARS, and anthrax. Classes will include lecture, primary literature reading and analysis, and some in-class small group work. Student performance will be assessed by weekly quizzes (60%), presentation of an assigned paper (10%), and a cumulative final exam (30%). **(not for advanced credit if taken as part of the PhD first year curriculum). 3 hr. Spring (Kasman).

MBIM-788. Spring Selective: Immunobiology.  Intensive 7-week introductory immunology course for graduate students in lecture format, utilizing Janeway’s Immunobiology as a textbook. Emphasis is on understanding molecular mechanisms resulting in immunity, and experimental methods for testing and discovering these mechanisms. **(not for advanced credit if taken as part of the PhD first year curriculum). 3 hr. Spring (Atkinson).

MBIM-856. Critical Literature Review, Inflammation and Immunity. Course is a formalized, refereed journal club focused on topics of general interest in Microbiology and Immunology. Papers are limited to those published in high impact journals, e.g. Nature, Science or Cell, in the areas of microbiology and immunology. For each paper, two faculty members (chosen by the course director) will be designated as referees. The names of the referees will be publically announced, and the faculty and student referees will grade the presenting student. In this case, the student will get feedback from both faculty members and their peers. The student referees will also provide detailed written critiques of both the paper and the presentation. All PhD candidates must enroll for 4 semesters or until graduation, whichever comes first. 1 hr. Spring/Fall (Sutkowski/Rubinstein).

MBIM-770. Seminar. ** Participation of graduate students in this course is mandatory. Guest speakers supplement the regular program. Each graduate student gives at least one seminar yearly. Pass/Fail **1 s.h. Fall and Spring (Voelkel-Johnson).

MBIM-970. Research. Variable s.h.

MBIM-980. Thesis. Variable s.h.

MBIM-990. Dissertation. Variable s.h.

M&I Students are also free to take advanced courses offered by other departments, provided the courses are approved for advanced credit by the student’s Advisory Committee.

Immunology and Microbiology courses offered by other departments:
CFSB-624. Oral ImmunoBiology. Oral Immunology-Oral Biology. Basic and clinical aspects of immunology are oriented toward oral biology with emphasis placed on salivary secretions, dental plaque, dental caries, the mucosal immune response, gingival crevicular fluid, periodontal disease and the acquired immuno-deficiency syndrome (AIDS). Laboratory demonstrations include a variety of immunological techniques used in research and diagnostic laboratories. Students are required to report on several manuscripts, which they choose from recent dental literature in the area of oral biology and oral immunology. In addition, students share this information in small group discussion. Merit graded. 4.0 s.h. Spring (Course director: Caroline Westwater PhD).

MCBP-802. Advanced Oral Microbiology & Immunology.  This course will teach microbiological and immunological concepts through in-depth study of infectious diseases. Emphasis will be placed on the major bacterial, fungal, and viral infections affecting the oral cavity and associated craniofacial structures. Course topics will focus on the pathogen, the host response to the pathogen, and strategies used to prevent or treat these diseases. Students will also be introduced to topics such as biofilm formation, quorum sensing, and the oral-systemic disease connection. Classes will include lecture and primary literature analysis. Student performance will be assessed by problem solving exercises, presentation of assigned paper(s), and exams. Merit graded. 3.0 s.h. Offered in spring or fall semester of alternate years. (Course director: Caroline Westwater PhD).

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