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 Marine Biomedicine and Environmental Sciences | Alumni | Brandon J. Cuthbertson
Brandon J Cuthbertson

Mentor: Dr. Paul Gross

Year Graduated: 2004

University/Degrees: East Carolina University, BS, MS

Post Doctoral: Fellow, Clemson University Genome Institute, 
National Institutes of Health/National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina
Thesis: Multiple Classes of Penaeidin Antimicrobial Peptides Expressed in Individual Shrimp Exhibit Microbial Target Specificity and a Class Specific Gain of Function in a Single Domain
Publications
Cuthbertson, B. J., Büllesbach, E. E., Etienne, K., Bachère, E., Fievet, J., Gross, P. S. (2005) Functional partitioning of the penaeidin antimicrobial peptide family from an individual shrimp and fungicidal activity against antibiotic resistant human pathogens. European Journal of Biochemistry submitted

Gueguen, Y., Garnier, J., Robert, L., Lefranc, M.-P., Mougenot, I., Lorgeril, J.d., Janech, M., Gross, P.S., Warr, G.W., Cuthbertson, B., et al. (2005) PenBase, the shrimp antimicrobial peptide penaeidin database: sequence-based classification and recommended nomenclature Developmental and Comparative Immunology, available online 5/19/05

Cuthbertson, B.J., Rickey, J., Wu, Y., Powell, G. and Tomkins, J. (2005) Exploitation of the daylily petal senescence model as a source for novel proteins that regulate programmed cell death in plants. Blume, Y. (editor). In NATO Cell Death Monograph. NATO ASI Series in Cell Biology (In Press).

Cuthbertson, B. J., Yang, Y., Bachère, E., Büllesbach, E. E., Gross, P. S and. Aumelas, A. (2005) Solution structure of synthetic penaeidin-4 with structural and functional comparisons to penaeidin-3. Journal of Biological Chemistry 280:16009-16018.

Cuthbertson, B. J., Büllesbach, E. E., Fievet, J., Bachère, E., and Gross, P. S. (2004) A new class (penaeidin class 4) of antimicrobial peptide from the Atlantic white shrimp (Litopenaeus setiferus) exhibits target specificity and an independent proline-rich-domain function. Biochemical Journal 381:79-86.

Roney, K. E., Cuthbertson, B. J., et al. (2004) Alternative splicing of major histocompatibility complex class II DXB transcripts in Xiphophorus fishes. Immunogenetics 56:462-466

Cuthbertson, B. J. Shepard, E. F., Chapman, R. W. and Gross, P. S. (2002) Diversity of the penaeidin antimicrobial peptides in two shrimp species. Immunogenetics 54:442-445.

Bartlett, T. C., Cuthbertson, B. J., Shepard, E. F., Chapman, R. W., Gross, P. S. and Warr, G. W. (2002) Crustins, homologues of an 11.5-kDa antibacterial peptide, from two species of penaeid shrimp, Litopenaeus vannamei and Litopenaeus setiferus. Marine Biotechnology 4:278-293.

McConnell, T. J., Godwin, U. B., Cuthbertson, B. J. (1998) Expressed major histocompatibility complex class II loci in fishes. Immunological Reviews 166:294-300.

Bartlett, T.C., B.J. Cuthbertson, E.F. Shepard, R.W. Chapman, P.S. Gross, and G.W. Warr. 2002. Crustins, homologues of an 11.5 kDa antimicrobial peptide, from two species of penaeid shrimp, Litopenaeus vannamei and L. setiferus. Marine Biotechnology (in press).

Cuthbertson, B.J., E.F. Shepard, R.W. Chapman, P.S. Gross. 2002. Diversity of the Penaeidin Antimicrobial Peptides in Two Species of Shrimp. Immunogenetics 54 (in press).

Meeting, Abstracts and Presentations

Brandon J. Cuthbertson, Eleanor F. Shepard, Robert W. Chapman, Gregory W. Warr, and Paul S. Gross. 2002. EST analysis reveals substantial diversity of penaeidin antimicrobial peptides, 10th Annual Plant Animal and Microbial Genome Conference, January, 2002, San Diego, poster presentation.

Brandon J. Cuthbertson, Eleanor F. Shepard, Robert W. Chapman, Gregory W. Warr, and Paul S. Gross. Diversity of the Penaeidin Antimicrobial Peptide Family in Two Species of Shrimp. MUSC Student Research Day 2001.

Thomas C. Bartlett, Paul S. Gross, Robert W. Chapman, Brandon J. Cuthbertson, Eleanor F. Shepard, and Gregory W. Warr. Characterization of a Putative Antibacterial Protein from the Penaeid Shrimps, Litopenaeus vannamei and L. Setiferus. MUSC Student Research Day 2001.
 
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