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 Marine Biomedicine and Environmental Sciences | Faculty | Taisen Iguchi, Ph.D.

Taisen Iguchi, Ph.D.

Research Interest:

Research interests are 1) developmental effects of estrogen and estrogenic chemicals on various animal species including fish, amphibians, reptiles and mammals, 2) molecular mechanism of persistent epigenetic changes in mouse reproductive tracts induced by perinatal estrogen exposure, 3) molecular mechanisms of environmental sex determination of water fleas, Daphnia magna and reptiles such as American alligators, 4) molecular evolution of steroid hormone receptors, 5) establishing systems biology for Daphnia magna and algae.

Selected Publications:

1. Miyagawa, S., Matsumaru, D., Murashima, A., Omori, A., Satoh, Y., Haraguchi, R., Motoyama, J., Iguchi, T., Nakagata, N., Hui, C.C. and Yamada, G. (2011). The role of sonic hedgehog-Gli2 pathway in the masculinization of external genitalia. Endocrinology, 152, 2894-2903.

2. Moore, B.C., Milnes, M.R., Kohno, S., Katsu, Y., Iguchi, T., Woodruff, T.K. and Guillette, L.J.Jr. (2011). Altered gonadal expression of TGF-β superfamily signaling factors in environmental contaminant-exposed juvenile alligators. J. Steroid Biochem. Mol. Biol., 127, 58-63.

3. Katsu, Y., Lange, A., Miyagawa, S., Urushitani, H., Tatarazako, N., Kawashima, Y., Tyler, C.R. and Iguchi, T. (2011). Cloning, expression and functional characterization of carp, Cyprinus carpio estrogen receptors and their differential activations by estrogens. J. Appl. Toxicol., (in press).

4. Lange, A., Katsu, Y., Miyagawa, S., Ogino, Y., Urushitani, H., Kobayashi, T., Hirai, T., Shears, J.A., Nagae, M., Yamamoto, J., Ohnishi, Y., Oka, T., Tatarazako, N., Ohta, Y., Tyler, C.R. and Iguchi, T. (2011). Comparative responsiveness to natural and synthetic estrogens of fish species commonly used in the laboratory and field monitoring. Aquat. Toxicol., (in press).

5. Myburgh, J.G., Huchzermeyer, F.W., Groenewald, H.B., Soley, J.T., Bekker, L.C., Booyse, D.G., Iguchi, T. and Guillette, L.J.Jr. (2011). Technique for the collection of clean urine from the Nile crocodile (Crocodylus niloticus). J. South African Vet. Assoc., (in press).

Taisen Iguchi, Ph.D.

Professor of Integrative Bioscience, National Institutes of Natural Sciences

Ph.D. University of Tokyo

Iguchi's Contact Information

National Institute for Basic Biology
5-1 Higashiyama, Myodaiji, Okazaki, Aichi 444-8787, Japan

Phone: (81)564-59-5235

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