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Division of Rheumatology & Immunology

MUSC Lupus Erythematosus (M.U.S.C.L.E.) Research Group

NewslettersInformational Podcasts & Videos | Lupus FAQ | Support Group | Clinical Research Studies | Learn About Us | Announcements

Lupus Patient Educational Program (Slides):

Check out the latest MUSCLE Newsletter:

Download Podcasts to learn more about lupus and meet our investigators:

" Lupus - Research & Treatment Update" by Dr. Diane Kamen

" Rheumatoid Arthritis " by Dr. Jim Oates

" Research and Treatment Update for Osteoarthritis" by Dr. Jim Oates

Lupus FAQ

Check out Dx.Lupus for answers to your Frequently Asked Questions (FAQ) about lupus

Lupus Support Group and Local Chapter of the Lupus Foundation of America

For information on the “Lupus: Listening and Learning Group” in Charleston, please contact Michele Singletary at 843-729-0289. Meetings are the 2nd Monday of every other month, from 6 p.m. to 7:30 p.m. in the Fellowship Hall of Mount Pleasant Presbyterian Church. All patients with lupus, family members, friends and supporters are invited!

Important Website Links to “Bookmark”!

For questions about Lupus Research at MUSC or to join our mailing list, please send an email to:

or call us at 1-866-859-6107 (toll-free) or 843-792-8997 (local to Charleston)

A list of our currently enrolling Lupus Clinical Studies can be found on the MUSC Clinical Research website

About Our Group

The Medical University of South Carolina Lupus Erythematosus research group (also known as M.U.S.C.L.E.) is comprised of faculty and staff with interests in clinical, translational, and basic research related to lupus and community outreach to improve knowledge and awareness of lupus. The M.U.S.C.L.E. faculty principal investigators include clinical and translational scientists Drs. Gary Gilkeson, Diane Kamen, Holly Mitchell, Jim Oates, Tasha Ruth, Melissa Cunningham, Hazel Breland, basic research scientists Tammy Nowling, John Zhang, and human genetics researcher Paula Ramos. Our clinical research effort includes investigator initiated observational and interventional studies and industry sponsored treatment trials for lupus.  Our investigator initiated studies are administered through the Clinical and Translational Research Center (CTRC) and focus on biomarkers of lupus and lupus nephritis disease activity, the impact of vitamin D and other environmental factors on autoimmune disease, biomarkers of atherosclerosis and bone health in lupus, oral health and lupus, and the role of stress in the lives of patients with lupus. Our industry sponsored trials are designed to test a variety of new therapies that are intended to be more targeted with fewer adverse effects compared to current therapies used for the treatment of lupus.  Our basic and translational research efforts focus on the role of reactive intermediates in the pathogenesis and disease damage involved in lupus, the role of complement in lupus, and genes involved in the regulation of inflammatory processes in lupus. Please visit our individual faculty pages to learn about each member’s research interests. Patients interested in participating in research are invited to contact one of our study coordinators to learn more details about our research trials.

Contact us at:
1-866-859-6107(toll-free) or 843-792-8997 (local) or email us at


See More M.U.S.C.L.E. Photos & Get Updates on Events

Lupus Group Announcements

Upcoming Lupus Webchats

      See what topics are coming up and access transcripts of previous webchats. Sponsored by the Lupus Foundation of America.

Check Out the New Videos from the LFA on YouTube!

Learn more about lupus and find out ways you can help bring greater attention and resources to lupus.

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