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College of Graduate Studies

Course Descriptions

MCR 700-01 Clinical Biostatistics -An introduction to basic and intermediate statistical techniques used to analyze and interpret data in health sciences and related fields.  Emphasis is on applications of these methods, with just enough derivation to understand the procedures.  Topics include descriptive statistics, graphical methods and probability with applications to epidemiology, discrete and continuous distributions, inference on means, nonparametric methods, and inference on proportions, contingency tables, correlation, analysis of variance, linear regression, logistic regression, and survival analysis.  Students will not be expected to run computer programs, but will learn how to read printout in order to interpret analytical results.

MCR 724-01 Intro to Clinical Trials - An emphasis will be placed on the concepts, study designs and procedures used in the implementation of clinical trials research studies.  The methodology and process used to access and analyze data as well as the collection of data will be described.

MCR 725-01 Grants Development for Clinical Research -  The objective of the course is to prepare the student to develop a draft grant application, the sections of a grant, IRB regulations and procedures, what reviewers look for and how to think like a reviewer, ethics, and developing a research budget.  Students will be given examples of successful grants and grants that have not been funded to discuss and critique.

MCR 731-01 Critical Review of the Literature-  It is assumed that students in this class have a solid foundation in research design and both parametric and nonparametric statistics. An emphasis will be placed on the competencies and processes necessary to review the scientific literature. In particular, the students will review the published and unpublished literature associated with clinical research results. The focus of the class will be the review of the types of scientific and clinical research manuscripts papers and reports produced from different study approaches.  

MCR 732-01 Comparative Effectiveness Research - This course explores the scope of outcomes studies for evaluating the effectiveness of medical care by emphasizing the development of study designs matched to the research question. The course explores frequently used observation study designs, techniques for evaluating and selecting health outcomes measures, and analytical approaches appropriate to conducting health outcomes research. This course will also cover the approaches used for interpretation and translation of CER data through decision models to compare the cost effectiveness of treatments. 

MCR 736-01 Clinical Epidemiology - This course provides an introduction to the discipline of epidemiology and its application to public health research and practice. The course is designed to provide a conceptual foundation for epidemiologic research and application, especially study designs, quantitative concepts and methods, analysis, and interpretation.

MCR 738-01 Clinical Research Introductions - This course provides students with the basic structure of clinical research, mentorship, resources for professional research available throughout the campus.  Emphasis will be placed on a variety of clinical research conducted on MUSC's campus.

MCR 746-01 Informatics and Data Management for Clinical  Research - This course is intended to introduce clinical researchers to research oriented data management and related basic topics in Informatics.  Students taking this course will learn about basic concepts in: relational database design, modern research data capture tools, clinical data warehousing, security risks and mitigations, privacy issues in electronic data, data standards, data mining and other related topics. Students will get hands-on experience with using modern database tools to solve specific scientific problems by attending the course labs.

MCR 750-01 Ethical Issues in Clinical Research - An emphasis will be placed on the ethical issues associated with clinical research and practice. The focus of the class will be the review of the competencies involved in the conduct of ethically responsible research. The process of assessing ethical issues in research and study will be described. The ethical considerations in study design; study implementation, data management, data analysis, data Interpretation and results presentation and publication will be described. 

MCR 752-01 Team Science in Clinical Research - An emphasis will be placed on the competencies and processes associated with the concepts of team science in translational research necessary to review the scientific literature.  Solving complex societal problems (e.g., environment, poverty, cancer, healthcare) requires the integration of specialized knowledge bases.  

MCR 789-02 Clinician Educator for the Clinical Researcher -  Education and training is an important component of the academic clinical investigator.  This novel clinician educator course provides the opportunity to advance career goals with the enhancement of effective teaching.

MCR 789-03 ST: Regression Analysis for Clinical Research - Regression analysis is at the heart of statistics, and a sound knowledge of regression methods will serve students well as they design and conduct research projects. We begin with simple linear regression and then consider extensions such as multiple predictors, nonlinear effects, categorical predictors, and interactions. Students will learn to evaluate model fit using statistics such as t, F, and R2 in addition to informal analysis based on observable data patterns.  We will rely heavily on graphical representations of the data and make use of plots of regression residuals.  Concepts and techniques of regression analysis will be taught based on carefully developed examples. This course is intended for anyone involved in analyzing data, but who does not specialize in statistics.  We will use computer software (mainly SAS) to examine data output, but students will only be required to read and understand the output.  Students are not responsible for computer programming.

MCR 789-04  ST:Community Engagement Research - This course provides a foundation for incorporating the principles and methods of CE in the development of community-academic research partnerships and implementing best practices of CEnR. Topics include social determinants of health, ethics and responsible conduct in CEnR,  and strategies to engage communities across phases of the research process.

MCR 789-07 ST: Industry/Regulatory -The course focuses on the conduct of clinical research, whether an investigator-initiated study or participation as a site in a industry sponsored clinical trial.  It will present in detail all aspects of clinical research including assessment of opportunities and feasibility, building a budget, negotiating contracts, managing regulatory requirements, and understanding intellectual property.

MCR 789-08 ST: Core Clinical Research Training - This course prepares participants to coordinate cost-effective health care research which protects the rights and safety of human subjects, achieves recruitment and retention outcomes and contributes to the science of health care.  Participants completing the training will be prepared to coordinate research studies in compliance with the Good Clinical Practice Guidelines and federal regulations concerning human subject research.  All participants of this course are required to take the CITI MIAMI Good Clinical Practice as a co-requisite.

MCR 789-13 ST:Contemporary Topics Seminar - The seminar was created to meet the thematic area of the core competencies in cross disciplinary training for student awareness of current issues in medical education and to focus on contemporary research study designs and techniques for application in patients populations.

MCR 789-20: Introduction to Grant Writing for Clinical and Translational Research - The course will function as an interactive description of the research grand mechanisms, application process, review process and implementation.  The different types of grants will be presented and the details of the application and peer review.  The source of funding will be described.  Students will learn an overview of the types of grants, potential funding sources, how to get started and resources available at MUSC.

MCR 789-32 ST: Leadership - This course introduces the major historical and contemporary theories of leadership in the workplace with emphasis on the principles and application of leadership skills. The course will include the study of organization structures, principles, techniques and processes as they relate to practice in and management of health services and research organizations.  Students should gain a better understanding of organizational behavior issues such as motivation, leadership, communication, interpersonal conflict, group dynamics, organizational structures, and meeting procedures.

MCR 970 Research - This is a varied credit hour research course determined by the student and mentor. A contract between the two includes material covered and deliverables at the end of the semester.

 
 
 

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