Department of Neuroscience
Ronald E. See, Ph.D.
BA, Psychology, 1984, University of California, Berkeley
MA, Psychobiology, 1985, University of California, Los Angeles
Ph.D., Psychobiology, 1989, University of California, Los Angeles
Neural substrates of addiction and relapse: Our laboratory has developed animal models of chronic psychostimulant and opiate self-administration to study the role of specific brain nuclei in mediating drug-taking and drug-seeking behavior. A particular focus is the role of corticolimbic function in regulating the learned associations that mediate relapse to compulsive drug abuse.
Sex differences in addiction: This line of research examines sex differences in a model of relapse to cocaine-seeking behavior produced by various stimuli. Further studies are using this model to examine sex differences in the response to possible pharmacotherapies for relapse.
Neural basis of antipsychotic drug effects: This research is directed towards understanding the mechanisms of short- and long-term antipsychotic drug action in the brain. These studies involve administration of a variety of drugs that affect basal ganglia function as measured by changes in neurotransmitter release via intracranial microdialysis.