E-Papers

(All files are in PDF format)

2012    2011    2010    2009    2008    2007    2006    2005    2004    2003    2001   2000   1999    1997    1994    1991

2012 E-Papers

• Angie M. Cason & Gary Aston-Jones. Role of orexin/hypocretin in conditioned sucrose-seeking in rats. Psychopharmacology (Berl). (2012).
  
• Brandon S. Bentzley, Kimberly M. Fender & Gary Aston-Jones. The behavioral economics of drug self-administration: A review and new analytical approach for within-session procedures. Psychopharmacology (Berl). (2012).
  
• Gregory C. Sartor and Gary Aston-Jones.  Regulation of the ventral tegmantal area by the bed nucleus of the stria terminalis is required for the expression of cocaine preference. Eur J Neurosci. 36(11):3549-3558 (2012).
  
• Stephen V. Mahler, Megan Hensley-Simon, Pouya Tahsili-Fahadan, Ryan T. LaLumiere, Charles Thomas, Rebecca V. Fallon, Peter W. Kalivas & Gary Aston-Jones.  Modafinil attenuates reinstatement of cocaine seeking: Role for cystine-glutamate exchange and metatropic glutamate receptors. Addict Biol. (2012).
  
• Stephen V. Mahler & Gary Aston-Jones.  Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats. JNeurosci. 32(38):13309-13326 (2012). 
  
• Luyi Zhou, Rachel J. Smith, Phong H. Do, Gary Aston-Jones & Ronald E. See.  Repeated orexin 1 receptor antagonism effects on cocaine seeking in rats. Neuropharmacology 63:1201-1207 (2012).
  
• Elena M. Vazey & Gary Aston-Jones.  The emerging role of norepinephrine in cognitive dysfunctionof Parkinson's disease. Front Behav Neurosci. 6:48 (2012).
  
• Andrea Bari & Gary Aston-Jones.  Atomoxetine modulates spontaneous and sensoy-evoked discharge of locus coeruleus noradrenergic neurons. Neuropharmacology (2012).
  
• Stephen V. Mahler, Rachel J. Smith, David E. Moorman, Gregory C. Sartor & Gary Aston-Jones. Multiple roles for orexin/hypocretin in addiction. Prog Brain Res. 198:79-121 (2012).
  
• Gregory C. Sartor & Gary Aston-Jones. A Septal-Hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference. J. Neurosci.32(13):4623-4631 (2012).
  
• Kimberlei Richardson & Gary Aston-Jones. Lateral Hypothalamic orexin/hypocretin neurons that project to ventral tegmental area are differentially activated with morphine preference. J Neurosci. 32(11):3809-17 (2012).
  
• Stephen V. Mahler, Rachel J. Smith & Gary Aston-Jones. Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology. Epub:13 March 2012.
  
• Rachel J. Smith & Gary Aston-Jones. Orexin/Hypocretin 1 receptor antagonist reduces heroin self-administration and cue-induced heroin seeking. Eur J Neurosci. 35(5):798-804 (2012).
  
• Kathryn J. Reissner, Gregory C. Sartor, Elena M. Vazey, Thomas E. Dunn, Gary Aston-Jones & Peter W. Kalivas. Use of vivo-morpholinos for the control of protein expression in the adult rat brain.  J Neurosci Methods. 203(2):354-360 (2012).

2011 E-Papers

• Rachel J. Smith & Gary Aston-Jones. α₂ Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking. Biol Psychiatry. 70(8):712-9 (2011).
• Alice H. Luo, Pouya Tahsili-Fahadan, Roy A. Wise, Carl R. Lupica, & Gary Aston-Jones.  Linking context with reward: A functional circuit from hippocampal CA3 to ventral tegmantal area. Science. 333(6040):353-7 (2011).
• Jason Lockrow, Heather Boger, Greg Gerhardt, Gary Aston-Jones,  David Bachman, & Ann-Charlotte Granholm. A noradrenergic lesion exacerbates neurodegeneration in a Down syndrome mouse model.  J. Alzheimers Dis. 23(3):471-89 (2011).
• Nieuwenhuis, S., De Geus, E.J. & Aston-Jones, G. The anatomical and functional relationship between the P3 and autonomic component of the orienting response. Psychophysiology. 48(2):162-175 (2011).

2010 E-Papers

• David E. Moorman & Gary Aston-Jones. Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: Diurnal influences. J. Neurosci. 30(46):15585-99. (2010).
• Pouya Tahsili-Fahadan, Greg V. Carr, Glenda C. Harris, & Gary Aston-Jones. Modafinil blocks reinstatement of extinguished opiate-seeking in rats: Mediataion by a glutamate mechanism. Neuropsychopharmacology. 35(11):2203-10. (2010).
• Gompf, H.S., Greenberg, J.H., Aston-Jones, G., Ianculescu, A.G., Scanlan, T.S., & Dratman, M.B. 3-Monoiodothyronamine: The rationale for its action as an endogenous adrenergic-blocking neuromodulator. Brain Res. 1351:130-40. (2010).
• Angie M.Cason, Rachel J. Smith, Pouya Tahsili-Fahadan, David E. Moorman, Gregory C Sartor, & Gary Aston-Jones, Role of orexin/hypocretin in reward-seeking and addiction: Implications for obesity. Physiol Behav. (2010).
  
• Valentino R, Aston-Jones G.Special issue on neuropeptides in stress and addiction: Overview.Brain Res. 1314:1-2 (2010).
• Pouya Tahsili-Fahadan, Robert Malcolm, & Gary Aston-Jones, Modafinil: an anti-relapse medication.Neuropsychopharmacology. 1:343-4. (2010).
  
• Gary Aston-Jones, Rachel J. Smith, Gregory C. Sartor, David E. Moorman, Lema Massi, Pouya Tahsili-Fahadan, & Kimberlei A. Richardson, Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction.Brain Res. 1314:74-90.(2010).
• Mark S. George & Gary Aston-Jones, Noninvasive techniques for probing neurocircuitry and treating illness: vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). Neuropsychopharmacology. 35(1):301-16.(2010).

2009 E-Papers

• Gompf H, Chen J, Sun Y, Yanagisawa M, Aston-Jones G, & Kelz MB. Halothane-induced hypnosis is not accompanied by inactivation of orexinergic output in rodents. Anesthesiology. 111(5):1001-9.(2009).

• Rachel J Smith & Gary Aston-Jones, Inactivating the activated:  identifying functions of specific neural networks.  Nature Neuroscience 12:8 (2009).
• Rachel J. Smith, Ronald E. See and Gary Aston-Jones, Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking.  Eur J of Neurosci, v 30, pp. 493–503 (2009).
• David E. Moorman, Gary Aston-Jones, Orexin-1 receptor antagonism decreases ethanol consumption and preference selectively in high-ethanolepreferring SpragueeDawley rats.  Alcohol 43 (2009).
• Carlos A. Mejías-Aponte, Candice Drouin, and Gary Aston-Jones, Adrenergic and Noradrenergic Innervation of the Midbrain Ventral Tegmental Area and Retrorubral Field: Prominent Inputs from Medullary Homeostatic Centers.  The Journal of Neuroscience, 29(11):3613–3626 (2009). 
• Gary Aston-Jones and Joshua I. Gold, How We Say No: Norepinephrine, Inferior Frontal Gyrus, and Response Inhibition.  Biol Psychiatry 65:548–549 (2009).
• David E. Moorman and Gary Aston-Jones, Optical control of reward.  Nature 458:23 (2009).
• Rachel J. Smith, Pouya Tahsili-Fahadan, Gary Aston-Jones, Orexin/hypocretin is necessary for context-driven cocaine-seeking.  Neuropharmacology xxx (2009).
• Gary Aston-Jones, Rachel J. Smith, David E. Moorman, Kimberlei A. Richardson, Role of lateral hypothalamic orexin neurons in reward processing and addiction.  Neuropharmacology 56:112–121 (2009).

2008 E-Papers

• Aston-Jones, G., Smith, R.J., Morman, D.E., and Richardson, K.A.,  Role of lateral hypothamic neurons in reward processing and addiction. Neuropharmacol. (2008)
• Smith, R.J., and Aston-Jones, G. Noradrenenrgic transmission in the extended amygdala: role of increased drug-seeking and relapse during protracted drug abstinence.  Brain Struct Funct. 213(1-2):43-61 (2008).
• Gompf, H.S., and Aston-Jones, G., Role of orexin input in the diurnal rhythm of locus coeruleus impulse activity.  Brain Res. 1224:43-52 (2008)
• Aston-Jones, G., and Kalivas, P.W., Brain norepinephrine rediscovered in addition research.  Biol Psychiatry 63(11):1005-1006 (2008).
• Gonzalez, M.M., and Aston-Jones, G., Light deprivation damages monoamine neurons and produces a depressive behavioral phenotype in rats. Proc Natl Acad Sci USA. 105(12)4898-4903 (2008).
• Luo, A.H., Georges, F.E., and Aston-Jones, G., Novel neurons in ventral tegmental area fire selectively during the active phase of the diurnal cycle.  Eur J Neurosci. 27(2): 408-422.

2007 E-Papers

• Aston-Jones, G., Iba, M., Clayton, E., and Rajkowski, J., and Cohen, J., The Locus Coeruleus and Regulation of Behavioral Flexibility and Attention: Clinical Implications. In: Ordway, G.A., Schwartz, M.A., Frazer, A. (Eds.), Brain Norepinephrine: Neurobiology and Therapeutics, Cambridge University Press, pp. 196-235 (2007).
• Aston-Jones, G., Gonzalez, M., and Doran, S., Role of the Locus Coeruleus-Norepinephrine System in Arousal and Circadian egulation of the Sleep-Wake Cycle.  In: Ordway, G.A., Schwartz, M.A., Frazer, A. (Eds.), Brain Norepinephrine: Neurobiology and Therapeutics, Cambridge University Press, pp. 157-195 (2007).
• Harris, G., Wimmer, M., Randall-Thompson, J.F., and Aston-Jones, G., Lateral Hypothalamic Orexin Neurons are Critically Involved in Learning to Associate an Environment with Morphine Reward. Behav Brain Res. 183:43-51 (2007).
• Harris, G., Hummel, M., Wimmer, M., Mague, S.D., and Aston-Jones, G., Elevations of FosB in the Nucleus Accumbens during Forced Cocaine Abstinence Correlate with Divergent Changes in Reward Function. Neurosci. 147:583-591 (2007).
• Harris, G., and Aston-Jones, G., Activation in Extended Amygdala Corresponds to Altered Hedonic Processing during Protracted Morphine Withdrawal.  Behav Brain Res. 176(2):251-258 (2007).

2006 E-Papers

• Gonzalez, M., and Aston-Jones, G., Circadian Regulation of Arousal: Role of the Noradrenergic Locus Coeruleus system and Light Exposure.  Sleep. 29(10):1327-1336 (2006).
• Harris, G., and Aston-Jones, G., Arousal and Reward: A Dichotomy in Orexin Function. Trends Neurosci. 10: 571-7. (2006).
• Georges, F., Le Moine, C. and Aston-Jones, G., No Effect of Morphine on Ventral Tegmental Dopamine Neurons during Withdrawal. J. Neurosci. 26: 5720-5726 (2006).

2005 E-Papers

• Aston-Jones, G., Card, J.P., Zhu, Y., Gonzalez, M., and Haggerty, E., The NE System as a Target for Hypocretin Neurons: Implications for Regulation of Arousal. In: DeLecea, L., Sutcliffe, G. (Eds.), Hypocretins: Integrators of Physiological Functions, Kluwer/Springer, pp. 137-152 (2005).
• Aston-Jones, G., Cohen J. D., Adaptive Gain and the Role of the Locus Coeruleus-Norepinephrine System in Optimal Performance. J. Comp. Neurol. 493(1): 99-110. (2005).
• Nieuwenhuis S., Aston-Jones G., Cohen J. D., Decision Making, the P3, and the Locus Coeruleus - Norepinephrine System. Psychol Bull. 131(4): 510-532. (2005).
• Aston-Jones, G. and Cohen, J. D., An Integrative Theory of Locus Coeruleus-Norepinephrine Function: Adaptive Gain and Optimal Performance. Ann. Rev. Neurosci. 28: 403-450 (2005).
• Harris, G., Wimmer, M. and Aston-Jones, G., A Role for Lateral Hypothalamic Orexin Neurons in Reward Seeking. Nature 437: 556-559 (2005).

2004 E-Papers

• Harris, G., Wimmer, M., Byrne, R., and Aston-Jones, G., Glutamate-associated Plasticity in the Ventral Tegmental Area is Necessary for Conditioning Environmental Stimuli with Morphine. Neuroscience 129 (3): 841-847 (2004).
• Aston-Jones G., Zhu Y., Card J.P., Numerous GABAergic Afferents to Locus Ceruleus in the Pericerulear Dendritic Zone: Possible Interneuronal Pool. J. Neurosci. 24(9): 2313-2321. (2004).
• Aston-Jones, G., and Harris, G., Brain Substrates for Increased Drug Seeking During Protracted Withdrawal. Neuropharmacology 47S1: 167-179 (2004).
• Rajkowski J., Majczynski H., Clayton E., Aston-Jones G., Activation of Monkey Locus Coeruleus Neurons Varies with Difficulty and Performance in a Target Detection Task. J. Neurophysiol. 92(1): 361-371. (2004).
• Clayton, E., Rajkowski, J., Cohen, J. D., and Aston-Jones, G., Phasic Activation of Monkey Locus Ceruleus Neurons by Simple Decision in a Forced-Choice Task. J. Neurosci. 24 (44): 9914-9920 (2004).

2003 E-Papers

• Harris, G., and Aston-Jones, G., Altered Learning and Motivation Following Opiate Withdrawal: Evidence for Prolonged Dysregulation of Reward Processing. Neuropsychopharmacology 28: 865-871 (2003).
• Harris, G., and Aston-Jones, G., Enhanced Morphine Preference Following Prolonged Abstinence: Associationwith Increased Fos Expression in the Extended Amygdala. Neuropsychopharmacology 28: 292-299 (2003).

2001 E-Papers

• Georges, F., and Aston-Jones, G., Potent Regulation of Midbrain Dopamine Neurons by the Bed Nucleus of the Stria Terminalis. J. Neurosci. 21: RC160 (1-6) (2001).
• Aston-Jones, G., Chen, S., Zhu, Y., and Oshinsky, M., A Neural Circuit for Circadian Regulation of Arousal. Nature Neurosci. 4: 732-738 (2001).

2000 E-Papers

• Delfs, J., Zhu, Y., Druhan, J., and Aston-Jones, G., Noradrenaline in the Ventral Forebrain is Critical for Opiate Withdrawal-induced Aversion. Nature 403: 430-434 (2000).

1999 E-Papers

• Horvath, T. L., Peyron, C., Diano, S., Ivanov, A., Aston-Jones, G., Kilduff, T. S., Van Den Pol, A. N., Hypocretin (Orexin) Activation and Synaptic Innervation of the Locus Coeruleus Noradrenergic System. J. Comp Neurol. 415(2): 145-159. (1999).
• Usher, M., Cohen, J. D., Servan-Schreiber, D., Rajkowski, J., and Aston-Jones, G., The Role of the Locus Coeruleus in the Regulation of Cognitive Performance. Science 283: 549-554 (1999).

1997 E-Papers

• Aston-Jones, G., Rajkowski, J., Kubiak, P., Conditioned Responses of Monkey Locus Coeruleus Neurons Anticipate Acquisition of Discriminative Behavior in a Vigilance Task. Neuroscience. 80(3): 697-715. (1997).
• Aston-Jones, G., Hirata, H., and Akaoka, H., Local Opiate Withdrawal in Locus Coeruleus in vivo. Brain Res. 765:331-336 (1997).

1994 E-Papers

• Aston-Jones, G., Rajkowski, J., Kubiak, P., and Alexinsky, T., Locus Coeruleus Neurons in Monkey Are Selectively Activated by Attended Cues in a Vigilance Task. J. Neurosci. 14: 4467-4480 (1994).

1991 E-Papers

• Akaoka, H., and Aston-Jones, G., Opiate Withdrawal-induced Hyperactivity of Locus Coeruleus Neurons is Substantialy Mediated by Augmented Excitatory Amino Acid Input.  J. Neurosci. 11(12): 3830-3839 (1991).
• Aston-Jones, G., Akaoka, H., Charlety, P., and Chouvet, G., Serotonin Selectively Attenuates Glutamate-Evoked Activation of Noradrenergic Locus Coeruleus Neurons. J. Neurosci. 11(3): 760-769 (1991).