(All files are in PDF format)

• Aston-Jones, G., Iba, M., Clayton, E., and Rajkowski, J., and Cohen, J., The Locus Coeruleus and Regulation of Behavioral Flexibility and Attention: Clinical Implications. In: Ordway, G.A., Schwartz, M.A., Frazer, A. (Eds.), Brain Norepinephrine: Neurobiology and Therapeutics, Cambridge University Press, pp. 196-235 (2007).
• Aston-Jones, G., Gonzalez, M., and Doran, S., Role of the Locus Coeruleus-Norepinephrine System in Arousal and Circadian egulation of the Sleep-Wake Cycle.  In: Ordway, G.A., Schwartz, M.A., Frazer, A. (Eds.), Brain Norepinephrine: Neurobiology and Therapeutics, Cambridge University Press, pp. 157-195 (2007).
• Harris, G., Wimmer, M., Randall-Thompson, J.F., and Aston-Jones, G., Lateral Hypothalamic Orexin Neurons are Critically Involved in Learning to Associate an Environment with Morphine Reward. Behav Brain Res. 183:43-51 (2007).
• Harris, G., Hummel, M., Wimmer, M., Mague, S.D., and Aston-Jones, G., Elevations of FosB in the Nucleus Accumbens during Forced Cocaine Abstinence Correlate with Divergent Changes in Reward Function. Neurosci. 147:583-591 (2007).
• Aston-Jones, G., Card, J.P., Zhu, Y., Gonzalez, M., and Haggerty, E., The NE System as a Target for Hypocretin Neurons: Implications for Regulation of Arousal. In: DeLecea, L., Sutcliffe, G. (Eds.), Hypocretins: Integrators of Physiological Functions, Kluwer/Springer, pp. 137-152 (2005).
• Harris, G., and Aston-Jones, G., Activation in Extended Amygdala Corresponds to Altered Hedonic Processing during Protracted Morphine Withdrawal.  Behav Brain Res. 176(2):251-258 (2007).
• Gonzalez, M., and Aston-Jones, G., Circadian Regulation of Arousal: Role of the Noradrenergic Locus Coeruleus system and Light Exposure.  Sleep. 29(10):1327-1336 (2006).
• Harris, G., and Aston-Jones, G., Arousal and Reward: A Dichotomy in Orexin Function. Trends Neurosci. 10: 571-7. (2006).
• Georges, F., Le Moine, C. and Aston-Jones, G., No Effect of Morphine on Ventral Tegmental Dopamine Neurons during Withdrawal. J. Neurosci. 26: 5720-5726 (2006).
• Aston-Jones, G., Cohen J. D., Adaptive Gain and the Role of the Locus Coeruleus-Norepinephrine System in Optimal Performance. J. Comp. Neurol. 493(1): 99-110. (2005).
• Georges, F., and Aston-Jones, G., Potent Regulation of Midbrain Dopamine Neurons by the Bed Nucleus of the Stria Terminalis. J. Neurosci. 21: RC160 (1-6) (2001).
• Nieuwenhuis S., Aston-Jones G., Cohen J. D., Decision Making, the P3, and the Locus Coeruleus - Norepinephrine System. Psychol Bull. 131(4): 510-532. (2005).
• Aston-Jones, G. and Cohen, J. D., An Integrative Theory of Locus Coeruleus-Norepinephrine Function: Adaptive Gain and Optimal Performance. Ann. Rev. Neurosci. 28: 403-450 (2005).
• Harris, G., Wimmer, M., Byrne, R., and Aston-Jones, G., Glutamate-associated Plasticity in the Ventral Tegmental Area is Necessary for Conditioning Environmental Stimuli with Morphine. Neuroscience 129 (3): 841-847 (2004).
• Aston-Jones G., Zhu Y., Card J.P., Numerous GABAergic Afferents to Locus Ceruleus in the Pericerulear Dendritic Zone: Possible Interneuronal Pool. J. Neurosci. 24(9): 2313-2321. (2004).
• Aston-Jones, G., and Harris, G., Brain Substrates for Increased Drug Seeking During Protracted Withdrawal. Neuropharmacology 47S1: 167-179 (2004).
• Rajkowski J., Majczynski H., Clayton E., Aston-Jones G., Activation of Monkey Locus Coeruleus Neurons Varies with Difficulty and Performance in a Target Detection Task. J. Neurophysiol. 92(1): 361-371. (2004).
• Delfs, J., Zhu, Y., Druhan, J., and Aston-Jones, G., Noradrenaline in the Ventral Forebrain is Critical for Opiate Withdrawal-induced Aversion. Nature 403: 430-434 (2000).
• Harris, G., and Aston-Jones, G., Altered Learning and Motivation Following Opiate Withdrawal: Evidence for Prolonged Dysregulation of Reward Processing. Neuropsychopharmacology 28: 865-871 (2003).
• Harris, G., and Aston-Jones, G., Enhanced Morphine Preference Following Prolonged Abstinence: Associationwith Increased Fos Expression in the Extended Amygdala. Neuropsychopharmacology 28: 292-299 (2003).
• Clayton, E., Rajkowski, J., Cohen, J. D., and Aston-Jones, G., Phasic Activation of Monkey Locus Ceruleus Neurons by Simple Decision in a Forced-Choice Task. J. Neurosci. 24 (44): 9914-9920 (2004).
• Aston-Jones, G., Chen, S., Zhu, Y., and Oshinsky, M., A Neural Circuit for Circadian Regulation of Arousal. Nature Neurosci. 4: 732-738 (2001).
• Horvath, T. L., Peyron, C., Diano, S., Ivanov, A., Aston-Jones, G., Kilduff, T. S., Van Den Pol, A. N., Hypocretin (Orexin) Activation and Synaptic Innervation of the Locus Coeruleus Noradrenergic System. J. Comp Neurol. 415(2): 145-159. (1999).
• Harris, G., Wimmer, M. and Aston-Jones, G., A Role for Lateral Hypothalamic Orexin Neurons in Reward Seeking. Nature 437: 556-559 (2005).
• Aston-Jones, G., Rajkowski, J., Kubiak, P., Conditioned Responses of Monkey Locus Coeruleus Neurons Anticipate Acquisition of Discriminative Behavior in a Vigilance Task. Neuroscience. 80(3): 697-715. (1997).
• Aston-Jones, G., Hirata, H., and Akaoka, H., Local Opiate Withdrawal in Locus Coeruleus in vivo. Brain Res. 765:331-336 (1997).
• Aston-Jones, G., Rajkowski, J., Kubiak, P., and Alexinsky, T., Locus Coeruleus Neurons in Monkey Are Selectively Activated by Attended Cues in a Vigilance Task. J. Neurosci. 14: 4467-4480 (1994).
• Usher, M., Cohen, J. D., Servan-Schreiber, D., Rajkowski, J., and Aston-Jones, G., The Role of the Locus Coeruleus in the Regulation of Cognitive Performance. Science 283: 549-554 (1999).
• Akaoka, H., and Aston-Jones, G., Opiate Withdrawal-induced Hyperactivity of Locus Coeruleus Neurons is Substantialy Mediated by Augmented Excitatory Amino Acid Input.  J. Neurosci. 11(12): 3830-3839 (1991).
• Aston-Jones, G., Akaoka, H., Charlety, P., and Chouvet, G., Serotonin Selectively Attenuates Glutamate-Evoked Activation of Noradrenergic Locus Coeruleus Neurons. J. Neurosci. 11(3): 760-769 (1991).