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Translational Research Unit (TRU)


The MUSC Brain & Spine Tumor Program at the Medical University of South Carolina Hollings Cancer Center is committed to state of the art care for patients with tumors of the nervous system. The efforts of a highly dedicated professional team are focused on providing the most effective therapies available while also striving to develop new therapies within a highly active laboratory and clinical research program. These efforts are backed by facilities with the latest technology in neurosurgery, neuropathology, neuroimaging, radiation oncology and bench research.

The MUSC Hollings Cancer Center Brain & Spine Tumor Program strives to serve the brain tumor population in South Carolina and neighboring states. The participation in neuro-oncology multi-center and group trials brings the latest in neuro-oncology care to the region.

For more information on MUSC Neuro-Oncology, visit the MUSC Brain & Spine Tumor Program website.


Study Coordinator: Michele DeCandio, RN

PI Information:

Bruce Frankel, M.D.

Title: Associate ProfessorDr. Frankel

- Brain tumors
- Adult spinal deformity
- Spinal tumors
- Minimally invasive and complex spinal surgery

- Stereotactic radiosurgery
- Focused beam therapy
- Gamma knife surgery

- Vertebral fracture program
- Kyphoplasty 

Advanced Degree: M.D. awarded by SUNY Upstate Medical University, 1994

Residency: SUNY Upstate Medical University

Fellowship: SUNY Upstate Medical University

Specialties: Neurosurgery

Board Certified: Neurological Surgery

Language(s): English

Arabinda Das, Ph.D.

Title: Research Assistant ProfessorDr. Arabinda Das

- Neuro-oncology (Brain Tumor)
- Apoptosis
- ALK/c-Met, TGF-β, CDK4/6, Sonic Hedgehog and Notch Pathways
- Drug Resistance
- Tumor Suppressor gene
- HDAC inhibitors
- Molecular and Radiation therapy
- Gliomas
- Cancer biology
- Anticancer effect of new pipeline drugs

Education: Ph.D., 1999, Utkal University, Bhubaneswar, India


2000 - 2001: Research Associate, Molecular Biology- Duke University Medical Center, Durham, NC
2001- 2003: Postdoctoral Fellow, Biochemistry and Molecular Biology - Medical University of South Carolina, Charleston, SC
2003 - 2008: Postdoctoral Fellow, Neurosciences (Neurology) - Medical University of South Carolina, Charleston, SC

Neuro-Oncology Clinical Trials:

View available neuro-oncology clinical trials

Other Resources:

American Brain Tumor Association
National Brain Tumor Society


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