Lawrence Judson Chandler, Ph.D.
BS, Biology, 1980, Birmingham Southern College
PhD, Pharmacology, 1988, The University of Texas at Austin
Dr. Chandler’s research program is focused on understanding the fundamental processes that underlie the plasticity of the nervous system. In particular, his laboratory is investigating how the brain changes and adapts in response to environmental influences such as exposure to drugs of abuse and alcohol. It is widely believed that changes in glutamatergic neurotransmission mediate the neuroadaptive processes of addiction and tolerance. Areas of research interest include receptor trafficking and synaptic localization, signal transduction, and dendritic spine dynamics. Techniques being employed include cell culture, molecular and biochemical procedures, confocal and multiphoton imaging, and in vitro electrophysiology.