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Endocrinology Current and Recent Research

SEARCH for Diabetes in Youth: South Carolina Center.  (NIH)
Natural History Study of the Development of Type 1 Diabetes (Trial Net TN01) (NIH/NIDDK)
A multicenter, Phase 3, randomized, open-label, active-controlled, parallel-group trial investigating the safety, tolerability, and efficacy of TransCon hGH administered once a week versus standard daily hGH replacement therapy over 52 weeks in prepubertal children with growth hormone deficiency (GHD) 
Comparison of VRS-317, a Long-acting Human Growth Hormone, to Daily rhGH in a Phase 3 Randomized, One-year, multi-center, non-inferiority trial in Pre-pubertal Children with Growth Hormone 
An observational, longitudinal, prospective, long-term registry of patients with hypophosphatasia 
Retrospective Hypophosphatasia (HPP) EMR Analysis 
A Phase IV, Multicenter, Open-Label Study of the Immunogenicity of Nutropin AQ V1.1[Somatropin 9rDNA Origin Injection] administered daily to Naïve growth hormone-deficient children 
A Multi-center, Observational Registry of Pediatric Female Patients with Central Precocious Puberty receiving Supprelin® LA (Histrelin Acetate), A Hydrogel Subcutaneous Implant 
Congenital Hypothyroidism in Pediatric Endocrinology 
Correlations between Hemoglobin A1C and Body Mass Index Change in Pediatric Endocrinology Newly Diagnosed with All Types of Diabetes Exposed to an Instructional Tool. 
Increlex TM Growth Forum Database—IGFD Registry: A Patient Registry for Monitoring Long-term Safety and Efficacy of IncrelexTM.  
Correlations between Hemoglobin A1C and Body Mass Index Change in Pediatric Endocrinology Patients Newly Diagnosed with All Types of Diabetes from 2009-2010. 
A post-marketing, multicenter, two-arm registry of the implantation and explanation of Supprelin LA (histrelin acetate) subcutaneous implant and Vantas (histrelin implant) subcutaneous implant. 
A multicenter observational study of pediatric female patients with central precocious puberty receiving Supprelin LA (histrelin acetate), a hydrogel subcutaneous implant.
A Four-Year Open-Label Multi-Center Randomized Two-Arm Study of Genotropin in Idiopathic Short Stature (ISS) Patients: Comparing An Individualized, Target-Driven Treatment Regimen To Standard Dosing of Genotropin. 
Recombinant Human Growth Hormone (rhGH) and Recombinant Human Insulin-like Growth Factor-I (rhIGF-I) Combination Therapy in Children with Short Stature Associated with IGF-I Deficiency: A Three-Year, Randomized, Multi-center, Open-label, Parallel-group, Active treatment controlled dose selection Trial.  
Genentech National Cooperative Growth Study (NCGS) Post-Marketing Surveillance Program for Nutropin AQ®, Nutropin®, Nutropin Depot® and Protropin®. 
A Multicenter, Open-Label, Single Arm Study Assessing DYAD Perception of Convenience and Preference of the Newly Developed Genotropin Mark VII Pen.  
Recombinant Human Insulin-Like Growth Factor-I (rhIGF-I) Treatment of Short Stature Associated with Primary IGF-I Deficiency: A Multi-center, Open-label, Concentration-controlled Trial. 
Growth Hormone Monitor Patient Registry. 
Stressors in Pediatric Diabetes Patients
Pediatric Transgender Population in Endocrinology Clinic 
SEARCH for Diabetes in Youth: Pilot Study to Ascertain Cases of Diabetes in Youth using the MUSC Clinical Data Warehouse 
Diabetic Transition Quality Improvement Project 
Diabetic Ketoacidosis - A Chart Review 
Norditropin Registry.  
Eli Lilly’s Genesis Study.
Do Diabetics at MUSC Meet the ADA Recommendations for A1C Monitoring and Goals in the Outpatient Setting?
A 24-week, randomized, open-label, parallel group multinational comparison of Lantus® (insulin glargine) given in the morning as once-a-day basal insulin versus NPH insulin, in children with Type 1 diabetes mellitus aged at least 1 year to less than 6 years.
Pfizer’s International Growth Study (KIGS).
Phase Three, Randomized, Multi-center, Open-label Study to Evaluate the Efficacy and Safety of Leuprolide Acetate 11.25 mg and 30 mg Formulations in Children with Central Precocious Puberty.
Environmental Compounds and Sexual Precocity in South Carolina. 
External Continuous Infusion of Novolog versus Humalog: An Open-Label, Randomized, Parallel Group, Multi-center Study in Children and Adolescents with Type 1 Diabetes
Genentech National Cooperative Metabolic Study of Nutropin AQ ® and Nutropin ® and Nutropin AQ Pen ® for Replacement Therapy in Adults with Growth Hormone Deficiency (NCMS).



Named Best Children's Hospital

The U.S. News & World Report rankings place the MUSC Children’s Hospital heart program among the top 20 in the country. Six MUSC Children’s Hospital divisions are honored in the rankings:

  • Cardiology & Heart Surgery
  • Nephrology
  • Urology
  • Cancer
  • Gastroenterology & GI Surgery
  • Neurology & Neurosurgery



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