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Darby Children’s Research Institute and Pediatric Research Day

Please join us on Friday, March 24, 2017, 8am-4:30pm!

MUSC Bioengineering Building, 1st Floor, Room 110

Complete Program Book

Keynote Presentation: “Vitamin D, Immunity and Human Health: Are We There Yet?”

Martin Hewison, PhD

Martin Hewison, PhD
Professor of Molecular Endocrinology
Deputy Director Institute of Metabolism and Systems Research
The University of Birmingham Medical School
Birmingham, UK.

Friday, March 24, 2017, 8:00 AM – 9:00 AM

The last 10 years have witnessed a dramatic shift in our view of vitamin D. Increased awareness of the detrimental effects of vitamin D-deficiency, and the identification of numerous potential health benefits of supplementation have made vitamin D a hot research topic. What is the next step? The translational potential of vitamin D may be endorsed via the many randomized control trials currently underway, but do we really understand how vitamin D impacts human health? Beyond its classical actions in calcium and skeletal homeostasis, the answer is usually no. One facet of vitamin D physiology that has attracted much attention is its interaction with the immune system. The ability of vitamin D to promote both innate (macrophage/dendritic cell) and adaptive (T cell/B cell) responses, has linked vitamin D to infectious and autoimmune disorders. The presentation will review these actions in a translational setting, whilst highlighting recent advances that may provide a platform for improved use of vitamin D in future supplementation trials.  

Learning objectives:
1) To familiarize participants with the cellular components of innate and adaptive immunity, and the key targets for antimicrobial and anti-inflammatory immunity
2) To understand why vitamin D-deficiency is linked to immune disease
3) To enable participants to appreciate the different forms of vitamin D that may impact human health 

Named Best Children's Hospital

The U.S. News & World Report rankings place the MUSC Children’s Hospital heart program among the top 20 in the country. Six MUSC Children’s Hospital divisions are honored in the rankings:

  • Cardiology & Heart Surgery
  • Nephrology
  • Urology
  • Cancer
  • Gastroenterology & GI Surgery
  • Neurology & Neurosurgery


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