Cell and Molecular Pharmacology & Experimental Therapeutics
Department of Cell and Molecular Pharmacology & Experimental Therapeutics
Kenneth D. Tew, PhD, DSc
Thank you for viewing the Department of Cell and Molecular Pharmacology & Experimental Therapeutics webpage. There is tremendous opportunity for students and postdoctoral fellows interested in joining our department. Over the last few years, laboratory space has been renovated, additional core facilities created and expanded, and new faculty recruited. Faculty research interests encompass disease-oriented research topics including drug discovery, cancer therapeutics, stress responses and redox pathways, G protein signaling in aging and neurological disorders, kinase signaling, epigenetics and cancer, neurological pathologies, proteomics in signaling and cancer.
Why Choose Pharmacology
The Pharmacology Graduate Training Program is well suited for students seeking a connection between the basic and clinical sciences. It is an integrative study that draws knowledge from several disciplines- biochemistry, molecular biology, and human physiology- to explain how drugs elicit therapeutic or toxic effects upon living organisms. Our studies are focused upon the discovery of biological mechanisms and the development of novel therapeutic agents to improve pathological conditions. Pharmacology is an extremely timely career track, as the utility of drugs in the management of disease is not likely to diminish. Pharmacology students obtain comprehensive training focused on critical thinking and innovation. Pharmacology is an ideal program for M.D./Ph.D. students seeking a natural link between the basic and clinical sciences, and for students interested in careers in biotechnology or the pharmaceutical industry. Graduates from our program have successfully transitioned to careers in biomedical science within academia, the pharmaceutical industry, and government agencies.
- The Proteomics Center is housed within the department, and provides an opportunity for students and postdoctoral fellows to gain expertise that will prepare them for careers in academics or the pharmaceutical sector. The Thermo Orbitrap mass spectrometer enables the high-resolution analysis of protein post-translational modifications including glycosylation and phosphorylation. This newly acquired technology has supported growing research endeavors focused upon identifying biomarkers in human pathologies.
- Faculty members in Pharmacology hold two South Carolina Centers of Excellence Chairs. Funded programs emphasize our strengths in signaling and drug development. For example, the COBRE grant in Redox and Oxidative Signaling supports five independent faculty members and three core facilities, and provides a strong focus on how redox chemistry and biochemistry interface with pharmacology.
- As a result of these research strengths, in terms of NIH national ranking, the Department is now 27th out of 100 in terms of Medical School Pharmacology Departments. This is a very strong showing, especially when considering our modest size to that of larger departments at other Medical Schools.
- Interdisciplinary research endeavors with the College of Pharmacy, other departments within the College of Medicine and with the Hollings Cancer Center ensure a broad base of educational possibilities. Our department offers a wonderful opportunity to participate in, and contribute to, a greater understanding of drugs and how they work - all in a geographic location conducive to a high quality of life.