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Cell and Molecular Pharmacology & Experimental Therapeutics

Masters Program

Masters students are required to take 10 credits from the First Year Curriculum

These include the following 4 modules from CGS 701

1) Macromolecules: Proteins
    CGS 701L    (2 credits)  Fall

2) Receptors and Signaling
    CGS 701G    (2 credits)  Fall

3) Macromolecules: Nucleic Acids
    CGS 701K    (2 credits)  Fall

4) Regulation of Gene Expression
    CGS 701N    (2 credits)  Fall

In addition, students must take the following 2 modules from Essential Scientific Practices:

1) CGS 710: Essential Scientific Practices I (1 credit)

2) CGS 711: Diversity in Science (1 credit)

Students may choose between one of the following 2 electives:

1) PCOL 724/PHMSC 712. Drug Discovery and Molecular Pharmacology (3 credits)

This eight week spring elective explores the scientific principles underlying targeted drug design. Medicinal chemistry is integrated with molecular biology in the context of identifying tomorrow’s best-in-class drugs. The interdependence of pharmacodynamic and pharmacokinetic structure-activity relationships will be discussed as a prominent feature of drug discovery.

2) PCOL 721. Principles of Pharmacology (4 credits)

This fall elective develops an understanding of the principles required for conducting research studies involving the use of pharmacological agents as tools for understanding basic biological processes. The course covers basic principles of receptor theory, analysis of dose-response relationships, data interpretation, and the relationship between the chemistry of biological molecules and their cellular actions. These principles are developed in relation to signal transduction /cancer biology, functional genomics, and drug metabolism/toxicology. The course will impart an essential understanding of how pharmacological agents interact with living systems and how such actions are examined from an experimental point of view.