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Department of Public Health Sciences


BMTRY 736 : Foundations of Epidemiology (Epidemiology I)


This course provides an introduction to basic epidemiologic principles including measurements of disease occurrence, study designs (cohort, case-control, randomized clinical trials) and calculation of risk. Lecture material is supplemented with exercises and discussion of examples from the epidemiologic literature and presentations of epidemiologic studies by guest speakers.


  • Two Models: (1) Person-place-time (2) Host-agent environment
  • Data Summarization, Validity, Reproducibility
  • Variation in Measurement (Biologic vs. measurement error)
  • Displaying data (tables, graphs, charts)
  • Study Designs
  • Goals of Randomization in Clinical Trials
  • Causality, Evaluating Exposure-Disease Association
  • Screening & Diagnostic Tests
  • Predictive Value (+ and -)
  • Biases
  • Quantitative Measures: Frequency Ratios, Proportions, Rates Prevalence vs. Incidence
  • Estimation of Risk, Cumulative Incidence, Actuarial Method (Life Table), Incidence Density
  • Rates: Crude, Specific, Adjusted, Mortality Rates-sources
  • Standardization-Direct, Indirect Methods, Population standards
  • Measure of Association, Absolute vs. Relative Risk
  • Measure of Potential Impact, AR, PAR, PAR%
  • Statistical Testing
  • Descriptive studies
  • Case-Control Studies
  • Cohort studies
  • Intervention studies
  • Effect Modification
  • Confounding, Effects of Confounding


None.  Typically offered each year in the fall semester.


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