MUSC Nephrology Proteomics Facility
Facility Description
The MUSC Nephrology Proteomics Laboratory is a state-of-the-art facility capable of separation and identification of proteins in tissue, cells and body fluids. The major interest of our laboratory is biomarker discovery. To support this interest we have 2D gel separation, imaging and analysis tools, liquid chromatography, mass spectrometry and other protein separation tools. The facility is located on the 8th floor of the Clinical Science building and the 4th floor of the Strom Thurmond building at MUSC. |
Proteomics FacilityThe proteomics lab in the Nephrology Division at the Medical University of South Carolina focuses on renal biomarker discovery and pathophysiology of renal diseases. The laboratory uses two-dimensional gel electrophoresis, DIGE, free flow electrophoresis, protein identification by mass spectrometry, MALDI peptide analysis, liquid chromatography, isotopic labeling and other separation and proteomic techniques. The laboratory is a part of the MUSC Cardiovascular Proteomics Center and is the sample and data repository and the analytical lab for the Southern Acute Kidney Injury Network (SAKInet) and the Southeastern Kidney Disease Consortium(SEKDC). |
New Instrument Enables Rapid Identification of Biomarkers
| The MUSC nephrology proteomics lab has purchased a state-of-the-art mass spectrometer. The ABSciex 5600 Triple ToF mass spectrometer has brought exciting new capabilities to the lab for biomarker identification because of its extremely high mass accuracy and sensitivity. The instrument was purchased with a combination of funds from a VA grant and MUSC contributions. The mass spectrometer has been used to identify novel biomarkers that predict the development and progression of both diabetic nephropathy and acute kidney injury.
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