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MUSC Nephrology Proteomics Laboratory

Facility Description

The MUSC Nephrology Proteomics Laboratory is a state-of-the-art facility capable of separation and identification of proteins in tissue, cells and body fluids. The major interest of our laboratory is biomarker discovery and pathophysiology of renal diseases. To support this interest we perform liquid chromatography/mass spectrometry, 2D gel electrophoresis and other protein separation techniques. The facility is located on the 2nd  and 4th floor of the Strom Thurmond Building (STB) at MUSC. The laboratory is a sample repository and analytical lab for the proteomics laboratory.

New Instrument Enables Rapid Identification of Biomarkers

    Dr. Michael Janech (left)  
The MUSC nephrology proteomics lab has purchased a state-of-the-art mass spectrometer. The ABSciex 5600 Triple ToF mass spectrometer has brought exciting new capabilities to the lab for biomarker identification because of its extremely high mass accuracy and sensitivity. The instrument was purchased with a combination of funds from a VA grant and MUSC contributions. The mass spectrometer has been used to identify novel biomarkers that predict the development and progression of both diabetic nephropathy and acute kidney injury.



 SC Renal Disease Biomarkers SmartState Program Flow Chart 


 Proteomics Laboratory Contact Information:

Michael G. Janech, Ph.D.
Proteomics Laboratory Director
Associate Professor, Division of Nephrology
96 Jonathan Lucas St
Charleston, SC 29425
Linda Walker
Study Coordinator
Program Coordinator
Research Specialist
96 Jonathan Lucas St
Charleston, SC 29425
Phone: 843-792-4123 
Fax: 843-876-5129                                        
Phone: 843-792-2465 (Direct Line)
Fax: 843-792-8399

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