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MUSC Nephrology Proteomics Laboratory

Facility Description

The MUSC Nephrology Proteomics Laboratory is a state-of-the-art facility capable of separation and identification of proteins in tissue, cells and body fluids. The major interest of our laboratory is biomarker discovery and pathophysiology of renal diseases. To support this interest we perform liquid chromatography/mass spectrometry, 2D gel electrophoresis and other protein separation techniques. The facility is located on the 2nd  and 4th floor of the Strom Thurmond Building (STB) at MUSC. The laboratory is a sample repository and analytical lab for the Southern Acute Kidney Injury Network (SAKInet) and the Southeastern Kidney Disease Consortium (SEKDC).

New Instrument Enables Rapid Identification of Biomarkers

   Dr. John Arthur (right) and Dr. Michael Janech (left)  
The MUSC nephrology proteomics lab has purchased a state-of-the-art mass spectrometer. The ABSciex 5600 Triple ToF mass spectrometer has brought exciting new capabilities to the lab for biomarker identification because of its extremely high mass accuracy and sensitivity. The instrument was purchased with a combination of funds from a VA grant and MUSC contributions. The mass spectrometer has been used to identify novel biomarkers that predict the development and progression of both diabetic nephropathy and acute kidney injury.

 

Proteomics  Laboratory Organizational Chart

 Proteomics Laboratory Contact Information:

John Arthur, MD, PhD
DCI Endowed Chair in Nephrology
Professor
Director of the SC Renal Disease Biomarkers Program,
      Proteomics Laboratory and SEKDC
Divsion of Nephrology
829 CSB, MUSC
96 Jonathon Lucas St
Charleston, SC 29425
Elizabeth Shewfelt, MA, MS
Study Coordinator
Program Coordinator
RDB Newsletter Creator/Editor
Divison of Nephrology
829 CSB, MUSC
96 Jonathon Lucas St
Charleston, SC 29425
Phone: 843-792-4123 
Fax: 843-876-5129                                        
e-mail: arthurj@musc.edu
Phone: 843-792-6109 (Direct Line)
Fax: 843-876-5129
e-mail: shewfelt@musc.edu

 

 
 
 

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