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Desuo Wang, PhD

Title:

Assistant Professor

Office:

Coker Life Sciences Building
Room 611

Office Phone:803-777-7101
Lab Phone:803-576-6300
Research Area:Cardiac ion channel 
E-mail:wang@cop.sc.edu

Education

University of Florida, 1989-1995; Ph.D. (Pharmacology)
Shanxi Medical University, Taiyuan (China), 1978-1985; M.B./M.S.
(Medicine,Neurophysiology)

Description of Research Program
Cardiac ion channel protein function and regulation at normal and diseased conditions.

Selected Publications
Shryock J, Song YJ, Wang D, Baker SP, Olsson RA, Belardinelli L: Selective A2 adenosine receptor agonists do not alter action potential duration, twitch shortening, or cAMP accumulation in guinea pig, rat, or rabbit isolated ventricular myocytes. Circ. Res., 1993; 72: 194 205
Wang D and Belardinelli L: Mechanism of the negative inotropic effect of adenosine in guinea pig atrial myocytes. Am. J. Physiol., 1994; 267: H2420 29
Belardinelli L, Shryock JC, Song Y, Wang D, and Srinivas M: Ionic Basis of the Electrophysiological Action of Adenosine on ardiomyocytes.The FASEB Journal, 1995; 9: 359 65 (review)
Wang D, Shryock JC, and Belardinelli L: Cellular basis for the negative dromotropic effect of adenosine on rabbit single atrioventricular nodal cells. Circ. Res., 1996; 78: 697 706
Wang D, Martens JR, Posner P, Sumners C, and Gelband CH: Angiotensin II regulation of intracellular culcium in astroglia cultured from rat hypothalamus and brainstem. J. Neurochem., 1996; 67:996 1004 
Martens JR, Wang D, Sumners C, Posner P, and Gelband CH: Angiotensin II type 2 receptor mediated regulation of rat neuronal K+ channels. Circ. Res., 1996; 79:302 09
Wang D, Gelband CH, Sumners C and Posner P: Mechanisms underlying the chronotropic effect of angiotensin II on cultured neurons from rat hypothalamus and brain stem. J. Neurophysol. 1997; 78:1013-20
Wang D, Sumners C, Posner P, and Gelband CH: A type K+ channels in neurons cultured from neonatal rat hypothalamus and brain stem: Modulation by Angiotensin II. J. Neurophysol. 1997; 78:1021-29
Wang D and Armstrong DL: Tetraethylammonium potentiates the activity of muscarinic potassium channels in guinea pig atrial myocytes. J. Physiol. 2000; 529 Pt 3:699-705
Wang D, Hall SK, Rossie S, and Armstrong DL: A se/thr protein phosphatase couples muscarinic receptors to K+ channel stimulation in atrial myocytes. 2001; submitted to JBC

Contact Information
Department of Pharmaceutical Sciences
280 Calhoun Street
Charleston SC 29425
Sandy Spence 843-792-3117