Psychiatry and Behavioral Sciences
Midlands Adolescent Project (MAP)
The research is a Stage II randomized clinical trial (RCT) to compare the experimental treatment, OPT-A, to an "active placebo" (Treatment as Usual) on key clinical indices from pre-treatment through 18 months. The RCT (n = 160) employs the treatment manual, quality assurance protocol, and therapist training protocol developed and successfully piloted in the Stage I study, to evaluate the efficacy of OPT-A for youth referred to outpatient treatment of co-occurring substance use and internalizing problems. Specific aims include: (1) Determine the efficacy of OPT-A to reduce substance use among youth presenting for outpatient treatment of co-occurring substance use and internalizing disorders; (2) Determine the efficacy of OPT-A to improve mental health and functioning among youth presenting for outpatient treatment of co-occurring substance use and internalizing disorders; and (3) Examine consumer satisfaction for OPT-A. In addition to the main aims of the study, two exploratory aims will pursue preliminary mechanisms of action (MOA) research.
For more information, please contact Steve Shapiro (Project Manager) by phone at 843-876-1828, or by e-mail at firstname.lastname@example.org.
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