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Psychiatry and Behavioral Sciences

Psychiatry Grand Rounds Speaker


     C. Lindsay DeVane, Pharm.D.


C. Lindsay DeVane, Pharm.D., is Professor of Psychiatry and Behavioral Sciences and Vice Chair for Research in the Department of Psychiatry at MUSC.  He directs the Laboratory of Drug Disposition and Pharmacogenetics in the Darby Children’s Research Institute and oversees operation of the core laboratories of MUSC’s General Clinical Research Center. He received degrees in Pharmacy from the University of North Carolina, Mercer University in Atlanta, completed clinical residency training at Buffalo General Hospital and post-doctoral fellowship training in pharmacokinetics at the Millard Fillmore Hospital and the State University of New York at Buffalo.  In addition, he spent a sabbatical year training in the Laboratory of Clinical Science at the NIMH. 

Dr. DeVane is primarily a researcher with more than 275 publications and 120 abstracts involving many aspects of basic and clinical psychopharmacology.  His research has been funded by multiple NIH grants beginning in 1981 along with foundation and pharmaceutical industry support.  He is an elected member of the American College of Neuropsychopharmacology.  His research interests include development of new drugs to treat psychotic and mood disorders, psychoactive drug disposition and effects in pregnancy, and the role of drug transporters in psychopharmacology.  He is the Co-Editor-in-Chief of Human Psychopharmacology: Clinical and Experimental and named to the editorial board of seven additional journals.

         At the completion of this session, the participant should be able to:
          1) Describe how transporters influence drug concentration at sites of action. 
   2) Discuss the potential clinical consequences of altered transporter activity. 
   3) Describe how the genetics of drug transporters can influence the choice of 
        an antidepressant or antipsychotic.

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