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Psychiatry and Behavioral Sciences

Psychiatry Grand Rounds Speaker


     Mark S. George, M.D.


Mark S. George, MD is a distinguished Professor of Psychiatry, Radiology, and Neuroscience as well as Director of the Center for Advanced Imaging Research and the Brain Stimulation Laboratory at the Medical University of South Carolina, Charleston.  He received his medical degree and completed dual residencies at MUSC in both neurology and psychiatry and is board certified in both areas. 

After a fellowship in London in 1989, where he first encountered transcranial magnetic stimulation, and four years at the National Institute of Mental Health in Bethesda, Maryland, he returned to Charleston, where he has conducted pioneering work with functional imaging of the brain and several brain stimulation techniques, particularly TMS and vagus nerve stimulation.  He is on several editorial review boards, has published over 300 scientific articles or book chapters, holds eight patents, and has written or edited four books. 

Dr. George is the editor-in-chief of a new journal titled Brain Stimulation: Basic Translational and Clinical Research in Neuromodulation.  He resides in Sullivan’s Island, SC. 

         At the completion of this session, the participant should be able to:
  1. Know that there are a host of new techniques for stimulating the brain to treat depression, including new forms of ECT, and new techniques like TMS, VNS, DBS and EpCS.
  2. Be aware of the new advance in ECT whereby a shorter, more efficient pulse-width, called ultrabrief, can produce robust improvement with NO cognitive side effects.
  3. Be familiar with the latest clinical trial results involving daily prefrontal TMS and its regulatory status.
  4. Understand that we now know more about who responds to TMS, and which prefrontal brain regions are more likely to result in clinical remission.
  5. Realize that more invasive techniques are also being explored in research studies, including deep brain stimulation (constant or responsive) and epidural cortical stimulation.

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