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| SCOR Investigators | 
| CO-DIRECTORS: | Kathleen T. Brady, MD, PhD
Dr. Brady is the Director and PI of the MUSC SCOR. She is a full Professor at MUSC, psychiatrist and a pharmacologist with a lengthy record of federally funded clinical and translational research and considerable experience in teaching and research mentoring. She has achieved national and international prominence for her research in the area of psychiatric comorbidity and substance use disorders. Dr. Brady is also the PI for the NIH-sponsored Clinical Trials Network (CTN), which was initially funded in 2000 and funded again through competitive renewal in 2005. The MUSC site functions as one of a network of 17 CTN sites throughout the United States. Finally, Dr. Brady serves as the Program Director of the MUSC General Clinical Research Center (GCRC) and Associate Dean for Clinical Research in the College of Medicine at MUSC. Ronald E. See, PhD
Dr. See is a full Professor in the Department of Neurosciences and the Department of Psychiatry at MUSC. Dr. See has published more than 90 scientific papers and reviews and has made numerous national and international scientific presentations. Among his findings relevant to the SCOR are the development and application of a reinstatement model in rats for identifying the neural substrates of relapse. His current research has three major themes: (1) Neural substrates of addiction and relapse, using animal models of chronic psychostimulant and opiate self-administration to study the role of specific brain nuclei in mediating drug-taking and drug-seeking behavior, in particular the role of corticolimbic function in regulating the learned associations that mediate relapse to compulsive drug abuse; (2) Sex differences and the role of the estrous cycle in addiction, utilizing a model of relapse to drug-seeking behavior produced by various stimuli, and (3) Neural basis of antipsychotic drug effects, exploring mechanisms of short- and long-term antipsychotic drug action in the brain and specifically the differential mechanisms of typical vs. atypical antipsychotic drugs on motor function and basal ganglia neurochemistry. | | INVESTIGATORS: | Sudie Back, PhD Howard Becker, PhD Deanne Buffalari, PhD Matt Carpenter, PhD Stacia DeSantis, PhD Matt Feltenstein, PhD Karen Hartwell, MD Steve LaRowe, PhD Marcelo Lopez, PhD Megan Moran-Santa Maria, PhD Kimber Price, PhD Aimee McRae, PharmD, BCPP Carrie Randall, PhD Michael Saladin, PhD Annie Simpson, MSc
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