Psychiatry and Behavioral Sciences

Ongoing Studies

Here's a sampling of ongoing studies at the Department of Psychiatry and Behavioral Sciences

Oxytocin in Cocaine Dependence

  • Contact: Lisa Nunn 792-0476
  • The purpose of the study is to evaluate the effect of oxytocin on stress response and brain reactivity in individuals with cocaine dependence. Participation consists of a screening visit, three outpatient study sessions, and six brief follow-up visits.

Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects

  • Contact: Lisa Nunn 792-0476
  • This 12-week, multicenter, randomized, double-blind, placebo-pontrolled, parallel-group treatment study is investigating the effectiveness and safety of once-weekly intra-muscular Injections of TV-1380 (150 mg/week or 300 mg/week) in reducing cocaine use in people who frequently use cocaine. A contingency management intervention and cognitive behavioral therapy sessions are incorporated to encourage study engagement and retention.

Buspirone Treatment for Marijuana Dependence

  • Contact: Jessica 792-5819
  • This treatment study is investigating the effectiveness of the medication buspirone in reducing marijuana use in people who frequently use marijuana. A contingency management intervention and motivational enhancement therapy sessions are incorporated to encourage study engagement and retention.

Vilazodone Treatment for Marijuana Dependence

  • Contact: Jessica 792-5819
  • This treatment study is investigating the effectiveness of the medication vilazodone in reducing marijuana use in people who frequently use marijuana. A contingency management intervention and motivational enhancement therapy sessions are incorporated to encourage study engagement and retention.

A Randomized Controlled Trial of Varenicline for Adolescent Smoking Cessation

  • Contacts: Christine Horne 792-5807 or Lori Ann Ueberroth 792-8220  
  • This is a placebo-controlled smoking cessation treatment study for adolescents ages 14-21. After assessment and inclusion into the study, participants are randomized to receive a 12-week double blind course of varenicline or placebo. All participants concurrently receive weekly smoking cessation counseling and participate in a contingency management (CM) intervention, specifically designed to reinforce participant retention.

An Open-Label Pilot Trial of N-Acetylcysteine and Varenicline (Chantix®) in Cigarette Smokers

  • Contacts: Christine Horne 792-5807 or Erin McClure, Ph.D. 792-7192
  • The purpose of this study is to conduct a pilot feasibility trial of N-Acetylcysteine and Varenicline (Chantix®) in adult cigarette smokers, preliminarily assessing the tolerability and effects of this combination pharmacotherapy.
 
 
 

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