Office of Research Integrity
IBC Submission Process
Only MUSC faculty are eligible to submit IBC applications. Post-doctoral fellows, graduate students and visiting faculty must have the faculty member with whom they are working submit applications covering their work. The faculty member must be registered in the Provost’s Office Faculty Database to be able to submit on the Electronic Research Management applications System (ERMA).
MUSC IBC approval must be obtained to use the following for research:
- Recombinant DNA (rDNA)
- Microbes [Risk group (RG) 1-4] (including agents on the Select Agents list)
- Certain Biotoxins (including toxins on the Select Agents list)
The IBC requires registration of research involving the isolation, culture, or manipulation of known bloodborne pathogens (e.g. in blood, tissues, or cells). It is expected that investigators follow the Office of Risk Management's Blood Borne Pathogen (BBP) Exposure Control Plan for all other work involving human biological materials.
For research involving administration of these products to human subjects, special instructions apply for submission to the IBC.
Applications must be submitted prior to the initiation of work with the agent(s) being registered. The IBC meets monthly and submission deadlines are three weeks before the meeting. Submissions should be done in a timely manner as needed to permit:
- submission of grant proposals
- release of funds for approved proposals
- achievement of a satisfactory laboratory inspection conducted by the Institutional Biosafety Officer (BSO) as required for IBC approval
- release of approvals from other regulatory committees (IACUC and IRB) requiring IBC approval for their applications involving use of agents registered by the IBC.
Unless renewed by Continuing Review, an approved initial application is active for one year. For all approved applications (registrations), the IBC may determine that the research risk is of significant magnitude meriting review more frequently than on an annual basis. Prior to a registration’s expiration date, the IBC staff will send the Principal Investigator a timely reminder of approval expiration.
Amendments to registrations must be submitted prior to making a change in personnel, agents, procedures/practices, and facilities.