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SOUTH CAROLINA CLINICAL & TRANSLATIONAL RESEARCH INSTITUTE

Pilot Projects

       SCTR will facilitate new and innovative, interdisciplinary, high-impact translational research with emphasis on diseases demonstrating significant prevalence in South Carolina. SCTR supports applications across the translational spectrum - from basic science to population health - including patient-centered and community-engaged applications as well as applications from Early Career Investigators to shorten the time to research independence.


Learn more about SCTR's Pilot Project Program impact here

Click here to view SCTR Funded Pilot Projects

NEW NIH Requirements for Scientific Rigor and Transparency

Related Resources


Pilot Consults     

Biostatistics and Research Design

Budget and Justification

Regulatory (eg. IRB, consents)Intellectual Property

Community Engagement and
Special Populations

Technology Development and Intellectual PropertyClinical Data WarehouseStudy Feasibility & Recruitment
(for clinical trials)

SCTR INSTITUTE SPECIAL FUNDING OPPORTUNITY


MUSC SCTR Institute Program Funding Opportunity - NIH NCATS Clinical & Translational Science Award (CTSA) - Request for Applications

The MUSC SCTR Institute is currently planning a competing renewal application to be submitted in January 2019, with a project period limited to 5 years. As part of this competing renewal, two opti onal programs will also be submitted with this application. This announcement is a request for applications from eligible MUSC faculty to direct an optional program in SCTR’s grant renewal. Applications will be reviewed by SCTR leadership and internal advisors who will choose two optional programs to be included with the competing renewal application.

What Is An Optional Program?

An optional program of a Clinical and Translational Science Award is designed to supplement specific strengths and needs of the particular proposed CTSA Program hub (SCTR Institute). Each proposed optional program will require its own component. Examples of possible optional programs include genomics, phenotyping, biomarkers, drug discovery, preclinical development, imaging, or collaboration with Schools of Veterinary Medicine, rural health/telemedicine and others. Optional programs need to be feasible based upon unique opportunity and substantial prior experience. These optional programs may also focus on collaborations with other CTSA Program Hubs, for example to evaluate the effect of a new or existing tool or method on clinical and translational research at multiple hubs. Whenever possible, applicants should consider an experimental approach to evaluating innovations. Different components of one CTSA Program Hub, or several collaborating CTSAs could, for example, be randomized or cluster-randomized to the innovative approach, and then prospectively compared to those randomized to standard practice. This will allow for subsequent data driven decision making.

Key Dates:

Application Due: Friday, April 20, 2018

Anticipated Notification of Acceptance: Friday, May 4, 2018

Contact for Questions:

Ford Simmons III, MLIS
Special Projects Coordinator
South Carolina Clinical & Translational Research Institute  
simmonwi@musc.edu



SCTR INSTITUTE PILOT PROJECTS


Science of Team Science (SciTS) and Interprofessional and/or Interdisciplinary (IP/ID) Collaborations Small Grant Program Request for Applications (RFA)

Primary Objective: 
To generate pilot data on the value and impact of SciTS and IP/ID teamwork and initiatives.

Projects may focus on, but are not limited to, direct measurement of the impact of team work on research productivity, scientific innovation, patient outcomes, patient safety, cost-effectiveness of health care or research practice, health professional educational, training and clinical care outcomes (i.e. This RFA is not specifically targeted to see how many publications and grant applications would result from a specific team but rather how a particular team’s actions or behavioral changes might result in better outcomes). Projects may also focus on team science and interprofessional research tools and methodology such as the development/validation of relevant team science and interprofessional measurement tools, approaches and/or systems.

Key Dates:

Application Due: has been extended to by 5PM on Monday (EST), April 30, 2018

Earliest Anticipated Project Start Date: June 1, 2018

Contact for Questions:

Dayan Ranwala, PhD                                                             Jeff Borckardt, PhD
Associate Director                                                                  Professor and Assistant Provost
SCTR Pilot Project Program                                                  MUSC Office of Interprofessional Initiatives
and Team Science Program                                                    Director, SCTR Team Science Program
ranwala@musc.edu                                                                borckard@musc.edu         



High Innovation-High Reward Pilots
($10K / 12 months)
Purpose: To support new and interdisciplinary pilot projects that propose substantial development of intellectual property and/or commercialization opportunities.

Applications can be submitted on a "rolling" basis and will be reviewed within 3-4 weeks.
When an application is submitted please notify Dayan Ranwala at the email address below.

Once an application is submitted, the applicant SHOULD notify Dayan Ranwala using the email address below.

Contact: Dayan Ranwala, PhD - ranwala@musc.edu


SCTR - TWO SERVICES FOR EXTRAMURAL GRANT REVIEW ASSISTANCE

Objectives:

  • To provide help for the MUSC investigators who are submitting extramural grant applications.   
  • To increase the quality of the extramural grant application submissions and success of getting them funded.
  


SCTR Internal Scientific Review of Extramural Grant Application
Limited to MUSC Faculty; Internal SCTR/MUSC scientific review of an extramural grant application (NIH K-series, R-series, U-series, NSF applications)

Application Due Date: Minimum 6 weeks before the extramural grant application due to MUSC ORSP

Once an application is submitted, the applicant SHOULD notify Dayan Ranwala using the email address below.
Contact:  Dayan Ranwala, PhD - ranwala@musc.edu

  

External Review of Extramural Grant Application
Limited to MUSC Faculty; To engage an external expert to review an extramural grant application following SCTR internal approval* (NIH R-series, K-series, P-series, U-series, NSF applications)

* SCTR will make decisions whether to send these applications for external expert reviews based on the needs of the application.

Application Due Date: Minimum 6 weeks before the extramural grant application due  to MUSC ORSP

Once an application is submitted, the applicant SHOULD notify Dayan Ranwala using the email address below.
Contact: Dayan Ranwala, PhD - ranwala@musc.edu

  
To facilitate timely turnaround of the reviews, please submit all required components of the application, and other required information as listed in the "Information" sections.

Upon submission of an application (including the information above) to the SCTR application system, please notify Dayan Ranwala, PhD, via email (ranwala@musc.edu).

OTHER FUNDING: SCTR Voucher  |  Community Engagement  |  KL2  |  TL1  |  Research Toolkit: Funding & Grant Proposal


MUSC ONLINE LIBRARY OF SUCCESSFULLY FUNDED EXTRAMURAL RESEARCH PROPOSALS

This resource provides an online library of successfully funded extramural grant applications to aid in the preparation of new proposals - available to MUSC faculty upon request. These proposals are intended to be used as a tool for educational purposes, and not to be distributed outside of MUSC.

FUNDED PILOT PROJECTS

2007 - 2016 Funded Pilot Projects - PDF

Currently Funded

    

Christine Carr, MD
Palmetto Profiles
Associate Professor
Emergency Medicine
Project Title:
The HEART Pathway: A Learning Health System Project, Translating Evidence to Practice Across the Carolinas
Melanie L. Cason, PhD, RN, CNE
Palmetto Profiles
Assistant Professor
College of Nursing
Project Title:
Components of Team Science Implementation--What Contributes to Success?
Christine Cooper, MD
Palmetto Profiles
Assistant Professor
Neurology
Project Title:
Brain Circuitry Changes in Vascular Parkinsonism
Carla Danielson, PhD
Palmetto Profiles
Professor
Psychiatry and Behavioral Sciences
Project Title:
Trait Loci, PTSD, and Hazardous Alcohol Use
Cynthia B. Dodds, PhD
Palmetto Profiles
Assistant Professor
Division of Physical Therapy
College of Health Professions
Project Title:
Eye Spy for Development of Affective Qualities in Interprofessional Healthcare Students
Robert Gemmill, PhD
Palmetto Profiles
Professor
Medicine
Hematology/Oncology
Project Title:
Development of monoclonal antibodies to inhibit Neuropilin-2b-dependent metastasis
Colleen Hanlon, PhD
Palmetto Profiles
Associate Professor

College of Medicine
Psychiatry & Behavioral Sciences
Project Title:
Developing brain stimulation as a treatment for pain in opiate dependent individuals

Rochelle Hanson, PhD
Palmetto Profiles

Professor
Psychiatry & Behavioral Sciences
College of Medicine

Project Title:
Using Team Science to Integrate Primary Care and Behavioral Health for Trauma-Impacted Youth
Wei Jiang, MD
Palmetto Profiles
Assistant Professor
Medicine
Microbiology and Immunology
Project Title:
Monocyte dysfunction in HIV-infection

Kyu-Ho Lee, MD, PhD
Palmetto Profiles
Assistant Professor
Pediatrics

Project Title:
A Unique Mouse Model of Preeclampsia
Lisa McTeague, PhD
Palmetto Profiles
Assistant Professor
Psychiatry and Behavioral Sciences
Project Title:
Extinguishing Fear and Craving: Neuromodulating Shared Circuits

Anna-Liisa Nieminen, PhD
Palmetto Profiles
Associate Professor
Drug Discovery and Biomedical Sciences

Project Title:
Mechanisms of Mitochrondrial Iron Uptake - Potential New Therapeutic Target
Jean Marie Ruddy, MD
Palmetto Profiles
Assistant Professor
Medicine
Vascular Surgery
Project Title:
Correlating 4D flow MRI-derived shear stress to fenestration number in a tissue model of type B aortic dissection may predict false lumen thrombosis
Kit Simpson, DrPH
Palmetto Profiles
Professor
Healthcare Leadership & Management
Project Title:
Discovering Variations in Use and Outcomes in Three Stroke Rehabilitation Settings for Populations Defined by ADL, Age, Race, and Geography
Carol Wagner, MD
Palmetto Profiles
Professor
Pediatrics
Project Title:
Vitamin D Dependent Effects on Milk Fat Globule Membrane Structure and Composition
Jeremy Yu, MD, PhD
Palmetto Profiles
Associate Professor
Medicine
Endocrinology
Project Title:
Preeclampsia in minority pregnant women with Type 2 diabetes

LEADERSHIP

Perry V Halushka, PhD, MD
Program Director
halushpv@musc.edu
Kevin Gray, MD
Associate Program Director
graykm@musc.edu
Dayan Ranwala, PhD
Associate Director
843-792-1498
ranwala@musc.edu


 

 
 
 

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