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SOUTH CAROLINA CLINICAL & TRANSLATIONAL RESEARCH INSTITUTE

Pilot Projects

       SCTR will facilitate new and innovative, interdisciplinary, high-impact translational research with emphasis on diseases demonstrating significant prevalence in South Carolina. SCTR supports applications across the translational spectrum - from basic science to population health - including patient-centered and community-engaged applications as well as applications from Early Career Investigators to shorten the time to research independence.


Learn more about SCTR's Pilot Project Program impact here

Click here to view SCTR Funded Pilot Projects

NEW NIH Requirements for Scientific Rigor and Transparency

Related Resources


Pilot Consults     

Biostatistics and Research Design

Budget and Justification

Regulatory (eg. IRB, consents)Intellectual Property

Community Engagement and
Special Populations

Technology Development and Intellectual PropertyClinical Data WarehouseStudy Feasibility & Recruitment
(for clinical trials)

SCTR INSTITUTE PILOT PROJECTS


High Innovation-High Reward Pilots
($10K / 12 months)
Purpose: To support new and interdisciplinary pilot projects that propose substantial development of intellectual property and/or commercialization opportunities.

Applications can be submitted on a "rolling" basis and will be reviewed within 3-4 weeks.
When an application is submitted please notify Dayan Ranwala at the email address below.

Once an application is submitted, the applicant SHOULD notify Dayan Ranwala using the email address below.

Contact: Dayan Ranwala, PhD - ranwala@musc.edu


 

 

Multi-site CTSA “Carolinas Collaborative” Translational Research Pilot Program
Request for Applications on use of EHR for clinical research

($25K / 12 months)

What is the Carolina's Collaborative? (PDF)

Purpose:
This pilot program is designed to encourage and facilitate novel clinical and translational research that applies or accelerates discovery into testing in clinical or population settings. The proposed pilot work should collect preliminary data to lead to a competitive proposal submitted to an external funding agency (NIH, AHRQ, PCORI, foundation, etc.) within one year from onset of funding. Projects must demonstrate high translational potential with a clear path to subsequent grant support for a cohort study or clinical trial. Population health improvement projects should demonstrate significant stakeholder involvement to move it into broader practice patterns, clinical guidelines, and other applications.


Carolinas Collaborative has an existing harmonized dataset, called the Carolinas Collaborative Common Data Model (CDM). This means institutions store their electronic health record data in the same format, so that clinical data queries can be run across all member sites. The Carolinas Collaborative CDM includes several common types of data (e.g., diagnosis, procedures, labs, etc.) and is available for review here. Use of the Carolinas Collaborative CDM is a central component of this RFA (See Section III).

• Application Submission Deadline: 5pm, July 6, 2017
• Selection of Awardees: Mid-August 2017

Contact: Amanda Cameron - cameroa@musc.edu


COBRE in Stroke Recovery

Pilot Project Program
 
Overview:
COBRE in Stroke Recovery’s Pilot Project Program aims to attract additional junior and senior investigators into the field of stroke recovery research, promote utilization of the scientific cores, develop new collaborations and mentoring relationships, and stimulate new programmatic activities to build long-term sustainability of the Center. Please refer to the attached RFA for more details and how to apply.
 
Key Dates:
RFA Release Date: June 1, 2017
Letter of Intent Due Date: June 15, 2017, 5:00 p.m. EST, via email to LuAnne O’Connor at harleylu@musc.edu
Application Due Date: July 15, 2017, 5:00 p.m. EST
 
Contact for Questions:
Program related: Dr. Narendra Banik at baniknl@musc.edu
Administrative: LuAnne O’Connor at harleylu@musc.edu  

SCTR - TWO SERVICES FOR EXTRAMURAL GRANT REVIEW ASSISTANCE

Objectives:

  • To provide help for the MUSC investigators who are submitting extramural grant applications.   
  • To increase the quality of the extramural grant application submissions and success of getting them funded.
  


SCTR Internal Scientific Review of Extramural Grant Application
Limited to MUSC Faculty; Internal SCTR/MUSC scientific review of an extramural grant application (NIH K-series, R-series, U-series, NSF applications)

Application Due Date: Minimum 6 weeks before the extramural grant application due to MUSC ORSP

Once an application is submitted, the applicant SHOULD notify Dayan Ranwala using the email address below.
Contact:  Dayan Ranwala, PhD - ranwala@musc.edu

  

External Review of Extramural Grant Application
Limited to MUSC Faculty; To engage an external expert to review an extramural grant application following SCTR internal approval* (NIH R-series, K-series, P-series, U-series, NSF applications)

* SCTR will make decisions whether to send these applications for external expert reviews based on the needs of the application.

Application Due Date: Minimum 6 weeks before the extramural grant application due  to MUSC ORSP

Once an application is submitted, the applicant SHOULD notify Dayan Ranwala using the email address below.
Contact: Dayan Ranwala, PhD - ranwala@musc.edu

  
To facilitate timely turnaround of the reviews, please submit all required components of the application, and other required information as listed in the "Information" sections.

Upon submission of an application (including the information above) to the SCTR application system, please notify Dayan Ranwala, PhD, via email (ranwala@musc.edu).

OTHER FUNDING: SCTR Voucher  |  Community Engagement  |  KL2  |  TL1  |  Research Toolkit: Funding & Grant Proposal


MUSC ONLINE LIBRARY OF SUCCESSFULLY FUNDED EXTRAMURAL RESEARCH PROPOSALS

This resource provides an online library of successfully funded extramural grant applications to aid in the preparation of new proposals - available to MUSC faculty upon request. These proposals are intended to be used as a tool for educational purposes, and not to be distributed outside of MUSC.

FUNDED PILOT PROJECTS

2007 - 2016 Funded Pilot Projects - PDF

Currently Funded

    

Carl Atkinson, PhD
Palmetto Profiles
Associate Professor
Microbiology and Immunology
Project Title:
Discovery - Microenvironment Modifying Nano Carriers for the Therapy of Emphysema
Christine Carr, MD
Palmetto Profiles
Associate Professor
Emergency Medicine
Project Title:
The HEART Pathway: A Learning Health System Project, Translating Evidence to Practice Across the Carolinas
Bo Cen, PhD
Palmetto Profiles
Associate Professor
Hematology/Oncology
Project Title:
Targeting Pim-1 to Augment EGFR and ALK-Targeted Lung Cancer Therapies
Christine Cooper, MD
Palmetto Profiles
Assistant Professor
Neurology
Project Title:
Brain Circuitry Changes in Vascular Parkinsonism

James Cray, PhD
Palmetto Profiles
Assistant Professor
Oral Health Sciences

Project Title:
SCTR Tobacco Retreat Project - Does Nicotine Exposure Alter Craniofacial Development?
Carla Danielson, PhD
Palmetto Profiles
Professor
Psychiatry and Behavioral Sciences
Project Title:
Trait Loci, PTSD, and Hazardous Alcohol Use

Nathan Dolloff, PhD
Palmetto Profiles
Assistant Professor
Cell and Molecular Pharmacology and Experimental Therapeutics

Project Title:
Redox-Targeted Compound, E61, Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma

Wuwei Feng, MD MS FANA FAHA
Palmetto Profiles
Associate Professor
Neurology

Project Title:
Transcranial current stimulation device with safe application of higher currents and real-time monitoring

Monika Gooz, MD, PhD
Palmetto Profiles
Associate Professor
Drug Discovery & Biomedical Sciences

Project Title:
Mitochondrial metabolism as novel therapeutic target in polycystic kidney disease (PKD)

Rochelle Hanson, PhD
Palmetto Profiles
Psychiatry & Behavioral Sciences
College of Medicine

Project Title:
Using Team Science to Integrate Primary Care and Behavioral Health for Trauma-Impacted Youth

Michael Janech, PhD
Palmetto Profiles
Associate Professor
Nephrology

Project Title:
Proton-Transfer-Reaction Mass Spectrometry Discovery Platform of Volatile Biomarkers for Acute Kidney Injury

Kyu-Ho Lee, MD, PhD
Palmetto Profiles
Assistant Professor
Pediatrics

Project Title:
A Unique Mouse Model of Preeclampsia
Lisa McTeague, PhD
Palmetto Profiles
Assistant Professor
Psychiatry and Behavioral Sciences
Project Title:
Extinguishing Fear and Craving: Neuromodulating Shared Circuits
Eric Meissner, MD, PhD
Palmetto Profiles
Assistant Professor
Medicine
Project Title:
HIV Cohort Database

Anna-Liisa Nieminen, PhD
Palmetto Profiles
Associate Professor
Drug Discovery and Biomedical Sciences

Project Title:
Mechanisms of Mitochrondrial Iron Uptake - Potential New Therapeutic Target

Chrystal Paulos, PhD
Palmetto Profiles
Assistant Professor
Microbiology and Immunology

Project Title:
Targeting CD26 to Augment T cell-mediated Anti-tumor Immunity

Alicia Privette, PhD
Palmetto Profiles
Assistant Professor
General Surgery
College of Medicine

Project Title:
Information Technology for Teamwork and Communication In Trauma (IT-TACIT)
Kit Simpson, DrPH
Palmetto Profiles
Professor
Healthcare Leadership & Management
Project Title:
Discovering Variations in Use and Outcomes in Three Stroke Rehabilitation Settings for Populations Defined by ADL, Age, Race, and Geography

Maria Spampinato, MD
Palmetto Profiles
Assistant Professor
Radiology & Radiological Science

Project Title:
Diffusional Kurtosis Imaging of the Corticospinal Tract and Motor Outcome Prediction in Acute Ischemic Stroke

Carol Wagner, MD
Palmetto Profiles
Professor
Pediatrics
Project Title:
Vitamin D Dependent Effects on Milk Fat Globule Membrane Structure and Composition

Gavin Wang, MD, PhD
Palmetto Profiles
Assistant Professor
Pathology & Lab Medicine
College of Medicine

Project Title:
ATS Prodrugs

Edith Williams, PhD, MS
Palmetto Profiles
Assistant Professor
Public Health Sciences

Project Title:
Peer Approaches to Lupus Self-Management: A Novel Lupus Peer Mentorship Intervention

Patrick Woster, PhD
Palmetto Profiles
Professor
Drug Discovery & Biomedical Sciences

Project Title:
Epigenetic Modulators for the Treatment of Sickle Cell Disease

Elizabeth Yeh, PhD
Palmetto Profiles
Assistant Professor
Cell and Molecular Pharmacology and Experimental Therapeutics

Project Title:
Glycosylation-based Liquid Biopsy Detection of Breast Cancer Metastasis


LEADERSHIP

Perry V Halushka, PhD, MD
Program Director
halushpv@musc.edu
Anthony Alberg, PhD, MPH
Associate Program Director
alberg@musc.edu
Christine Turley, MD
Associate Program Director
turleyc@mailbox.sc.edu
Dayan Ranwala, PhD
Associate Director
843-792-1498
ranwala@musc.edu


 

 
 
 

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