Yiannis Koutalos Curriculum Vitae
Education
Positions
Honors
Teaching Experience
University Service
Professional Service
Publications
| Institution | Degree | Years | Field |
| University of Athens, Greece | B.S. | 1979-1984 | Physics |
| Nuclear Research Center Democritos, Greece | Summer School | 1982 | |
| University of Illinois at Urbana-Champaign, IL | Ph.D. | 1984-1990 | Biophysics |
| Johns Hopkins University School of Medicine, Baltimore, MD | Postdoctoral | 1990-1992 | Neuroscience |
| University of Colorado at Denver | Graduate studies | 1997-1999 | Sociology |
| Years | Position | Institution | Department/Program |
| 1992-1995 | Research Associate | Johns Hopkins University School of Medicine | Neuroscience |
| 1995-2004 | Assistant Professor | University of Colorado School of Medicine | Physiology and Biophysics |
| 2002-2004 | Member | University of Colorado School of Medicine | Neuroscience Program |
| 2004-present | Associate Professor | Medical University of South Carolina | Ophthalmology |
| 2005-present | Associate Professor | Medical University of South Carolina | Neurosciences |
| 1979-1983 | Scholarship of the State Fellowship Foundation of Greece |
| 1985-present | Member, Honor society of Phi-Kappa-Phi |
| 1988 | Robert Emerson Memorial Grant Award, University of Illinois School of Life Sciences |
| 1991-1992 | Fight For Sight postdoctoral research fellowship |
| 2003 | Japan Society for the Promotion of Science Invitation Fellowship |
| 2003 | Teaching Excellence Award, University of Colorado School of Medicine |
| 2004 | Teaching Excellence Award (entire Physiology course), University of Colorado School of Medicine |
| 1984-1985 | University of Illinois at Urbana-Champaign | Graduate teaching assistant Introductory Human Physiology |
| 1996-2004 | University of Colorado Health Sciences Center | Responsible for teaching Respiratory Physiology |
| 1998-2004 | University of Colorado Health Sciences Center | Lecturer for Colorado Rural Health Scholars Program Lectures on Respiratory Physiology to high school students |
1999-2000 | University of Colorado at Denver | Course Instructor, Department of Sociology Research Methods for the Social Sciences, a one-semester course for juniors and seniors |
| 2005 | University of Colorado Health Sciences Center | Visiting lecturer Respiratory Physiology lectures to Medical students |
| 2006-2007 | Medical University of South Carolina | Small group instructor Introduction to Clinical Ethics, for second year Medical students |
| 2007 | Medical College of Wisconsin | Guest lecturer Lecture on “Phototransduction” for the Ion Channels and Signal Transduction Course |
| 2007 | Medical University of South Carolina | Student mentor Summer Undergraduate Research Program |
| 1995-2004 | Seminar Series Coordinator | Department of Physiology and Biophysics, University of Colorado School of Medicine |
| 2000-2004 | Faculty Senate | University of Colorado Health Sciences Center |
| 2004-2006 | Student Research Day Judge | Medical University of South Carolina |
| 2006 | Student Interprofessional Day Facilitator | Medical University of South Carolina |
| 2006-2007 | Research Project Grants Retreat review panel member | Medical University of South Carolina |
Grant review
Ad hoc reviewer for National Institutes of Health, National Science Foundation, and Human Frontier Science Program
Journal referee
Biophysical Journal; Proceedings of the National Academy of Sciences, U.S.A.; Journal of General Physiology; Journal of Physiology; Visual Neuroscience; Journal of Cell Science; Vision Research; IEEE Transactions in Biomedical Engineering; Journal of Neuroscience Methods; Investigative Ophthalmology and Visual Science; Journal of Biological Chemistry
Textbook review
Medical Physiology textbooks, Publisher Lippincott, Williams & Wilkins
Koutalos Y and Ebrey TG. Recent progress in vertebrate photoreception. Photochem Photobiol 44:809-17. 1986.
Apte DV, Koutalos Y, McFarlane DK, Dawson MJ and Ebrey TG. Phosphorus-31 nuclear magnetic resonance spectroscopy of toad retina. Biophys J 56:447-52. 1989.
Koutalos Y, Ebrey TG, Tsuda M, Odashima K, Lien T, Park MH, Shimizu N, Derguini F, Nakanishi K, Gilson HR and Honig B. Regeneration of bovine and octopus opsins in situ with natural and artificial retinals. Biochemistry 28:2732-9. 1989.
Jonas R, Koutalos Y and Ebrey TG. Purple membrane: surface charge density and the multiple effect of pH and cations. Photochem Photobiol 52:1163-77. 1990.
Koutalos Y, Ebrey TG, Gilson HR and Honig B. Octopus photoreceptor membranes. Surface charge density and pK of the Schiff base of the pigments. Biophys J 58:493-501. 1990.
Deng H, Manor D, Weng G, Rath P, Koutalos Y, Ebrey T, Gebhard R, Lugtenburg J, Tsuda M and Callender RH. A resonance Raman study of octopus bathorhodopsin with deuterium labeled retinal chromophores. Photochem Photobiol 54:1001-7. 1991.
Deng H, Manor D, Weng G, Rath P, Koutalos Y, Ebrey T, Gebhard R, Lugtenburg J, Tsuda M and Callender RH. Resonance Raman studies of the HOOP modes in octopus bathorhodopsin with deuterium-labeled retinal chromophores. Biochemistry 30:4495-502. 1991.
Koutalos Y. High-pH form of bovine rhodopsin. Biophys J 61:272-5. 1992.
Koutalos Y and Yau KW. A rich complexity emerges in phototransduction. Curr Opin Neurobiol 3:513-9. 1993.
Koutalos Y, Brown RL, Karpen JW and Yau KW. Diffusion coefficient of the cyclic GMP analog 8-(fluoresceinyl)thioguanosine 3',5' cyclic monophosphate in the salamander rod outer segment. Biophys J 69:2163-7. 1995.
Koutalos Y, Nakatani K, Tamura T and Yau KW. Characterization of guanylate cyclase activity in single retinal rod outer segments. J Gen Physiol 106:863-90. 1995.
Koutalos Y, Nakatani K and Yau KW. The cGMP-phosphodiesterase and its contribution to sensitivity regulation in retinal rods. J Gen Physiol 106:891-921. 1995.
Koutalos Y, Nakatani K and Yau KW. Cyclic GMP diffusion coefficient in rod photoreceptor outer segments. Biophys J 68:373-82. 1995.
Nakatani K, Koutalos Y and Yau KW. Ca2+ modulation of the cGMP-gated channel of bullfrog retinal rod photoreceptors. J Physiol 484:69-76. 1995.
Huang L, Deng H, Weng G, Koutalos Y, Ebrey T, Groesbeek M, Lugtenburg J, Tsuda M and Callender RH. A resonance Raman study of the C=N configurations of octopus rhodopsin, bathorhodopsin, and isorhodopsin. Biochemistry 35:8504-10. 1996.
Koutalos Y and Yau KW. Regulation of sensitivity in vertebrate rod photoreceptors by calcium. Trends Neurosci 19:73-81. 1996.
Huang L, Deng H, Koutalos Y, Ebrey T, Groesbeek M, Lugtenburg J, Tsuda M and Callender RH. A resonance Raman study of the C=C stretch modes in bovine and octopus visual pigments with isotopically labeled retinal chromophores. Photochem Photobiol 66:747-54. 1997.
Chen C, Nakamura T and Koutalos Y. Cyclic AMP diffusion coefficient in frog olfactory cilia. Biophys J 76:2861-7. 1999.
Koutalos Y. Intracellular spreading of second messengers. J Physiol 519:629. 1999.
Koutalos Y and Yau KW. Characterization of guanylyl cyclase and phosphodiesterase activities in single rod outer segments. Methods Enzymol 315:742-52. 2000.
Ebrey T and Koutalos Y. Vertebrate photoreceptors. Prog Retin Eye Res 20:49-94. 2001.
Fain GL, Matthews HR, Cornwall MC and Koutalos Y. Adaptation in vertebrate photoreceptors. Physiol Rev 81:117-151. 2001.
Koutalos Y, Nakatani K, Xiong W-H and Yau K-W. Phototransduction in retina rods and cones. Vision: The Approach of Biophysics and Neuroscience. Musio C. World Scientific. Singapore. 172-183. 2001.
Chen C, Jiang Y and Koutalos Y. Dynamic behavior of rod photoreceptor disks. Biophys J 83:1403-12. 2002.
Nakatani K, Chen C and Koutalos Y. Calcium diffusion coefficient in rod photoreceptor outer segments. Biophys J 82:728-39. 2002.
Nakatani K, Chen C, Yau KW and Koutalos Y. Calcium and phototransduction. Adv Exp Med Biol 514:1-20. 2002.
Winski SL, Koutalos Y, Bentley DL and Ross D. Subcellular localization of NAD(P)H:quinone oxidoreductase 1 in human cancer cells. Cancer Res 62:1420-4. 2002.
Chen C, Nakatani K and Koutalos Y. Free magnesium concentration in salamander photoreceptor outer segments. J Physiol 553:125-35. 2003.
Cornwall MC, Tsina E, Crouch RK, Wiggert B, Chen C and Koutalos Y. Regulation of the visual cycle: retinol dehydrogenase and retinol fluorescence measurements in vertebrate retina. Adv Exp Med Biol 533:353-60. 2003.
Pappa A, Chen C, Koutalos Y, Townsend AJ and Vasiliou V. Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage. Free Radic Biol Med 34:1178-89. 2003.
Tsina E, Chen C, Koutalos Y, Ala-Laurila P, Tsacopoulos M, Wiggert B, Crouch RK and Cornwall MC. Physiological and microfluorometric studies of reduction and clearance of retinal in bleached rod photoreceptors. J Gen Physiol 124:429-43. 2004.
Chen C, Tsina E, Cornwall MC, Crouch RK, Vijayaraghavan S and Koutalos Y. Reduction of All-trans Retinal to All-trans Retinol in the Outer Segments of Frog and Mouse Rod Photoreceptors. Biophys J 88:2278-2287. 2005.
Pappa A, Brown D, Koutalos Y, DeGregori J, White C and Vasiliou V. Human aldehyde dehydrogenase 3A1 inhibits proliferation and promotes survival of human corneal epithelial cells. J Biol Chem 280:27998-8006. 2005.
Ala-Laurila P, Kolesnikov AV, Crouch RK, Tsina E, Shukolyukov SA, Govardovskii VI, Koutalos Y, Wiggert B, Estevez ME and Cornwall MC. Visual cycle: Dependence of retinol production and removal on photoproduct decay and cell morphology. J Gen Physiol 128:153-69. 2006.
Wu Q, Chen C and Koutalos Y. Longitudinal Diffusion of a Polar Tracer in the Outer Segments of Rod Photoreceptors from Different Species. Photochem Photobiol 82:1447-1451, 2006.
Wu Q, Chen C and Koutalos Y. All-trans retinol in rod photoreceptor outer segments moves unrestrictedly by passive diffusion. Biophys J 91:4678-89. 2006.
Imanishi Y, Lodowski KH and Koutalos Y. Two-photon microscopy: shedding light on the chemistry of vision. Biochemistry 46:9674-84. 2007.
Wu Q, Blakeley LR, Cornwall MC, Crouch RK, Wiggert BN and Koutalos Y. Interphotoreceptor retinoid-binding protein is the physiologically relevant carrier that removes retinol from rod photoreceptor outer segments. Biochemistry 46:8669-79. 2007.