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Division of General Surgery

Biographical Overview for J. Matthew Rhett, PhD

Dr. Rhett received a BS in Molecular Biology, a BS in Biochemistry, and a BA in Chemistry from the College of Charleston, and his PhD in Biomedical Science from the Medical University of South Carolina. He completed his graduate and post-doctoral training under Dr. Robert G. Gourdie, studying structural and molecular biology of protein-protein interactions in the gap junction protein Cx43 . Dr. Rhett accepted a faculty appointment in the Department of Surgery in 2013. His research focuses on elucidating the role of connexin channel signaling in inflammatory responses during injury.

Recent Publications:

Grek C.L., Rhett J.M., Ghatnekar G.S. Cardiac to cancer: Connecting connexins to

clinical opportunity. FEBS Letters. 2014. doi: 10.1016/j.febslet.2014.02.047.

*Rhett, J.M., Fann, S.A., Yost, M.J. Purinergic Signaling in Early Inflammatory Events of the Foreign Body Response: Modulating Extracellular ATP as an Enabling Technology for Engineered Implants and Tissues. Tissue engineering Part B, Reviews. 2014. Epub 2013/11/28. Featured article.

*Rhett, J.M., Veeraraghavan, R., Poelzing, S., Gourdie, R.G. The perinexus: Sign-post on the path to a new model of cardiac conduction? Trends Cardiovasc Med, 2013. 23(6): p. 222-228. Cover article.


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