Training in Craniofacial and Oral Health Research (T-COHR) Junior Investigators: Daniella Ishimaru, Ph.D., Research Assistant Professor Department of Biochemistry and Molecular Biology Project Title: Drosha-dependent Alterations in miRNA Biogenesis and their Roles in HNSCCs Bei Liu, M.D., M.P.H., Assistant Professor Department of Microbiology and Immunology Project Title: Role of CD24-Siglec Signaling in the Initiation and Progression of Oral Cancer Walter Renne, DMD, Assistant Professor Department of Oral Rehabilitation Project Title: Generation of a Novel Bacteriostatic and Anti-Collagenolytic Dental Adhesive Through the Incorporation of Polyacrylic Acid Modified Copper Nanoparticles into Adhesive Resins Jing Zhou, DDS, PhD, MSD, Assistant Professor Department of Pediatric Dentistry & Orthodontics Project Title: Periodontal Disease as A Risk Factor for Colorectal Neoplasia Christine Kern, Ph.D., Assistant Professor Department of Regenerative Medicine & Cell Biology Project Title: Prrx Regulation of Extracellular Matrix Genes during Craniofacial Development
Andrew Jakymiw, Ph.D., Assistant Professor Department of Craniofacial Biology (Mentor: Besim Ogretmen, PhD) Project Title: Characterization of a Dicer mRNA splice variant in oral cancer
Visu Palanisamy, Ph.D., Assistant Professor Department of Craniofacial Biology Project Title: Molecular mechanisms of mRNA Stability in Human Saliva
Gunhild Sommer, Ph.D., Research Assistant Professor Department of Biochemistry & Molecular Biology Project Title: Role of La in protection against chemotherapy-induced apoptosis in oral SCC
Students: Michael DeFee, DSTP student (Mentor: Christopher Parsons, MD) Project Title: Targeting Membrane Associated HSP90 Inhibits Activation of Nuclear Factor Kappa B By Kaposi’s Sarcoma Associated Herpesvirus
Alfred Griffin, DSTP student (Mentor: Keith L. Kirkwood, DDS, PhD) Project Title: Role of MKP-1 in Skeletal Homeostasis
Bethany Herbert, DSTP student Jonathan Kuo, PhD student Clemson-MUSC Bioengineering (Mentor; Hai Yao, PhD) Project Title: Bioengineering Approach to Understanding TMJ Pathobiology
Haley Lindner, DSTP student (Mentor: Robin Muise-Helmricks, PhD) Project Title: Poly-N-Acetylglucosamine Nanofibers from a Marine Diatom Promote Wound Healing and Defensin Eexpression via an AKT1-Dependent Pathway
David Sentelle, DSTP student (Mentor: Besim Ogretmen, PhD) Project Title: Role of Ceramide in Inducing Lethal Autophagy in Head and Neck Cancer
Jessica Trombetta, DSTP student (Mentor: Amy Bradshaw, PhD) Project Title: the role of SPARC in the maintenance of collagen type I within the periodontal ligament - or - SPARC Knock Out Mice have Irregular Collagen Morphology in the Periodontal Ligament
Clemson-MUSC Bioengineering (Mentor: Hai Yao, PhD) Project Title: Biomechanical Characterization and Modeling of Human TMJ Disc
Clemson-MUSC Bioengineering Program Wenhui (Daniel) Jiang, PhD student currently in laboratory rotations Xiaoyi (Tina) Zhang, MSTP student (Mentor: Keith L. Kirkwood, DDS, PhD) Project Title: The role of mitogen-activated protein kinase phosphatase-1 in tumor progression
Postdoctoral Fellows:
Alexis Nagel, Ph.D. (Mentor: Lauren Ball) Project Title: The role of the nutrient-responsive O-GlcNAc modification of IRS-1 and -2 on insulin and IGF-1 signaling in osteoblasts
Sudha Talwar, Ph.D. (Mentor: Visu Palanisamy) Project Title: Regulation of RNA binding proteins in oral cancer progression
Wendy Vandenberg-Foels, Ph.D. (Mentor: Xuejun Wen) Project Title: (1) Endogenous Stem Cell Recruitment for Articular Cartilage Regeneration (2) Alveolar bone regeneration in extraction sockets
Clinical Fellows: Mary Gray, DMD (Mentor: Keith Kirkwood) Project Title: TTP in Periodontal Disease Progression
Justin McAbee, DMD (Mentor: Keith Kirkwood) Project Title: MKP-1 in Bacterial Mediated Bone Loss
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