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Student Profiles-Justin McAbee Project Title: Sexual Dimorphism in Periapical Inflammation and Bone Loss from MAP Kinase Phosphatase-1 Deficient Mice Project Description: Mitogen Activating Protein (MAPK) kinase phosphatase-1 (MKP-1) has been shown to be a key negative regulator of the MAP kinase pathways of the innate immune system. The impact of MKP-1 in an endodontic model has yet to be studied. Thus, the purpose of this study was to determine the role of MKP-1 in a bacterial-driven model of pathological endodontic bone loss. American Association of Endodontists Foundation grant recipient Above entitled project accepted for publication in Journal of Endodontics Mentor and Department Dr. Keith Kirkwood DDS, PhD |
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