Translational Research Unit (TRU)
Alzheimer's Research & Clinical Programs (ARCP)
What is Alzheimer's disease?
Alzheimer's disease (AD) interrupts important processes that keep neurons in the brain healthy. These interruptions cause nerve cells to stop working, lose connections with other nerve cells, and finally die. The destruction of nerve cells is what causes the memory failure, personality changes, problems carrying out daily tasks, and other features of the disease.
The brains of people with AD have a large amount of two abnormal structures - amyloid plaques and neurofibrillary tangles. This abundance usually occurs first in the areas of the brain that are responsible for making new memories.
The third main feature of AD is the loss of connections between cells. This leads to a decline in the ability of brain cells to function and ultimately to cell death.
For more information on Alzheimer's disease, visit the ARCP web site.
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Video: New Alzheimer's Gene Therapy [3:20]
Dr. Jacobo Mintzer discusses the clinical trial of a new gene therapy for Alzheimer's that uses a viral vector delivery...
Clincial Director: Courtney O'Neill, MHA
Study Coordinators: Arthur Williams; Jan Watts, RN; Amanda Watts; Beth Safrit, NP
PI Information:
Jacobo Mintzer, M.D. |
Title: Interest/Specialty: Geriatric research only Advanced Degree: M.D. awarded by Buenos Aires University, 1978 |
David Bachman, M.D. |
Title: Interest/Specialty: Advanced Degree: M.D. awarded by Emory University School of Medicine 1977 Residency: Emory University School of Medicine Fellowship: Boston University School of Medicine Specialties: Neurology Board Certified: Neurology Language(s): English |
ARCP Clinical Trials:
View a list of available ARCP clinical trials.
ARCP Location:
5900 Core Road, Suite 203
North Charleston, SC 29406
Alzheimer's Support:
Somerby of Mt. Plesant - 3rd Mon. 9:30 AM
Katie Jones 843-810-0342 or Bonnie Dewald 843-654-7919
Ebenezer AME Church (Downtown Charleston) - 3rd Wednesday monthly 5:30-6:30 pm
Shirley Brown 843-577-9267
Paulette Simmons 843-958-8595
Morris Brown AME Church (Downtown Charleston) - 4th Tuesday monthly 11am-12pm
Shirley Brown 843-577-9267
Paulette Simmons 843-958-8595
Martin Luther Evangelical Lutheran Church (James Island) - 2nd Tuesday monthly 6-7 pm
Patti Mears 843-795-3102
Episcopal Church of Our Savior (Johns Island) - 3rd Thursday monthly 1-2pm
Laura Stefanelli 843-478-8756
Franke at Seaside (Mount Pleasant) - 3rd Tuesday monthly 6:30-8pm
Karen Berry 843-856-4725
All Saints Lutheran Church (Mt. Pleasant) - 1st Wednesday monthly workshop 9:30-10:30am &
3rd Wednesday monthly support group 9:30-10:30am
Ginger Deignan 843-810-5576
Sunrise Presbyterian Church (Sullivan’s Island) - 2nd & 4th Wednesday 10:30-12pm
Sara Michelin 843-886-6510
Choices Women’s Center (West Ashley) - 2nd Thursday monthly 6:30-7:30pm
Edith Miller 843-763-1207
Ashley River Baptist Church (West Ashley) - Last Tuesday monthly 10am
John Ledford 843-766-5694
Bon Secours-St. Francis Hospital (West Ashley) - 1st Thursday monthly 7pm
John Ledford 843-766-5694
New First Missionary Baptist Church (Edisto Island) - 1st Tuesday monthly – 10:00 a.m.
Lula Grant 843-869-0279
NHC HealthCare of Charleston (Charleston) - 3rd Tuesdays monthly 6 p.m.
Ashley Gray and Kelley Martin 843-766-5228
Sweetgrass Memory Court (Mt. Pleasant) - 2nd Thursday monthly 6:30 p.m.
Tiffany Tolliver and Emilee Smoak 843-971-7756
Sea Island Adult Day Care (Johns Island) - Last Tues. 6 PM
Betty Brown 843-559-2504
Other Resources:
Alzheimer’s Association SC Chapter
Alzheimer’s Foundation of America
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North Charleston, SC 29406
Ph: 843-740-1592
Fax: 843-740-6113