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Structural Biology Center

Structural Biology Center Faculty

Director
Christopher Davies, PhD
Professor, Biochemistry and Molecular Biology
Structural basis for antibiotic resistance in pathogenic bacteria and development of new antimicrobials.

Deepak Bastia, PhD
Professor, Biochemistry and Molecular Biology
Structural analyses of the mechanisms of initiation of DNA replication of prokaryotic plasmids and the termination of DNA replication of plasmid, bacterial and yeast chromosomal, and human mitochondrial DNA.

John Baatz, PhD
Professor, Pediatrics
Developmental pulmonary biology, cystic fibrosis, lung injury and inflammation, lung toxicity and disease indigenous to South Carolina and to Southeastern coastal regions.

Craig Beeson, PhD
Associate Professor, Drug Discovery & Pharmaceutical Sciences
The regulation of energy metabolism and cell cycle progression.

Erika Bullesbach, PhD
Associate Professor, Biochemistry and Molecular Biology
Hormones of insulin-like structure. Chemical syntheses and structure-function relations.

Julie Chao, PhD
Professor, Biochemistry and Molecular Biology
Serine proteinases: Structure-function relationship.

Rosalie Crouch, PhD
Professor, Opthalmology
Using both natural and synthesized retinoids to probe the structure and function of the photosensitive pigments of the retina. G-protein coupled receptors that control the visual process.

Thomas A. Dix, PhD
Associate Professor, Drug Discovery & Pharmaceutical Sciences
Rational design of peptide-based therapeutics.

Starr Hazard, PhD
Associate Professor
Director of the Computational Biology Resource Center.
Structure and function of biological molecules. Bioinformatics tool development and molecular modeling. Drug discovery and signaling pathways.

Michael Janech, PhD
Associate Professor, Medicine, Division of Nephrology
Structure and function of ice-binding proteins from Antarctic diatoms and polar microorganisms.

Besim Ogretmen, PhD
Professor, Biochemistry and Molecular Biology
Structural analysis of telomere-binding proteins.

Shaun Olsen, PhD
Assistant Professor, Biochemistry and Molecular Biology
Structural basis by which ubiquitin is specifically conjugated to target proteins and for how ubiquitination acts as a molecular switch that regulates growth factor signaling pathways.

Rick Schnellmann, PhD
Professor and Chair, Drug Discovery & Pharmaceutical Sciences
Signaling pathways of cell injury, death (apoptosis and necrosis) in epithelial and cancer cells, and regeneration of epithelial cells following injury. Structure and function of mitochondrial calpains.

Adam J. Smolka, PhD
Professor, Department of Medicine, Division of Gastroenterology and Hepatology
Structure/function of membrane transporters.

Stephen Tomlinson, PhD
Professor, Microbiology and Immunology
Structural biology of the complement system.

Steven Rosenzweig, PhD
Professor, Cell and Molecular Pharmacology & Experimental Therapeutics
Structures of insulin-like growth factor binding proteins (IGFBPs).

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